Page last updated: 2024-10-27

fluoxetine and Bulimia Nervosa

fluoxetine has been researched along with Bulimia Nervosa in 18 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Bulimia Nervosa: An eating disorder that is characterized by a cycle of binge eating (BULIMIA or bingeing) followed by inappropriate acts (purging) to avert weight gain. Purging methods often include self-induced VOMITING, use of LAXATIVES or DIURETICS, excessive exercise, and FASTING.

Research Excerpts

ExcerptRelevanceReference
"In practice, in patients seeking treatment for bulimia nervosa, fluoxetine has been shown to provide only transient efficacy, and patients are exposed to the drug's adverse effects."7.73Fluoxetine. Bulimia nervosa: don't use. ( , 2006)
"This study compared the best available treatment for bulimia nervosa, cognitive-behavioural therapy (CBT) augmented by fluoxetine if indicated, with a stepped-care treatment approach in order to enhance treatment effectiveness."5.15Stepped care and cognitive-behavioural therapy for bulimia nervosa: randomised trial. ( Agras, S; Bryson, S; Crow, S; Fairburn, CG; Halmi, K; Kraemer, H; Mitchell, JE, 2011)
"Forty-five patients with bulimia nervosa were treated with the antidepressant fluoxetine and additionally with mood-stabilizers: 25 patients received carbamazepine and 20 patients - lamotrigine."5.14[Comparative effectiveness of mood stabilizers in the complex therapy of bulimia nervosa]. ( Marilov, VV; Sologub, MB, 2010)
" Antidepressants are commonly used to treat bulimia nervosa; high-dose fluoxetine is a standard approach, but many other antidepressants can be used."5.01Pharmacologic Treatment of Eating Disorders. ( Crow, SJ, 2019)
"Sertraline has been studied less extensively, and there have been a few studies concerning SSRIs that report follow-up data at more than 12 weeks of follow-up."2.73A randomized, double-blind trial comparing sertraline and fluoxetine 6-month treatment in obese patients with Binge Eating Disorder. ( Brustolin, A; Campisi, S; Fassino, S; Lavagnino, L; Leombruni, P; Pierò, A, 2008)
"Fluoxetine for BN and lisdexamfetamine for BED are relatively safe and well-tolerated."2.58Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder. ( Bello, NT; Yeomans, BL, 2018)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (33.33)29.6817
2010's10 (55.56)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Fornaro, M1
Mondin, AM1
Billeci, M1
Fusco, A1
De Prisco, M1
Caiazza, C1
Micanti, F1
Calati, R1
Carvalho, AF1
de Bartolomeis, A1
Yu, S1
Zhang, Y1
Shen, C1
Shao, F1
Gruber, M1
Jahn, R1
Stolba, K1
Ossege, M1
Himmerich, H1
Treasure, J1
Bello, NT1
Yeomans, BL1
Crow, SJ2
Paszyńska, E1
Słopień, A1
Węglarz, M1
Linden, RW1
Leombruni, P1
Pierò, A1
Lavagnino, L1
Brustolin, A1
Campisi, S1
Fassino, S1
Downe, KA1
Goldfein, JA1
Devlin, MJ1
Marilov, VV1
Sologub, MB1
Sysko, R1
Sha, N1
Wang, Y1
Duan, N1
Walsh, BT1
Mitchell, JE2
Agras, S1
Crow, S1
Halmi, K1
Fairburn, CG2
Bryson, S1
Kraemer, H1
Hay, PJ1
Claudino, AM1
Agras, WS1
Halmi, KA1
Nyman, JA1
Molinari, E1
Baruffi, M1
Croci, M1
Marchi, S1
Petroni, ML1
Rybakowski, F1
Slopien, A1
Komorowska, R1
Antkowiak, R1
Ciesielski, R1
Rajewski, A1
Grilo, CM1
Masheb, RM1
Wilson, GT1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Stepped Care vs Best Available Care for Bulimia Nervosa[NCT00733525]293 participants (Actual)Interventional2000-09-30Completed
Do Visuals of Symptom Change Increase Rates of Rapid Response in First Weeks of CBT for Eating Disorders?[NCT02940613]80 participants (Anticipated)Interventional2016-12-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for fluoxetine and Bulimia Nervosa

ArticleYear
Psychopharmacology of eating disorders: Systematic review and meta-analysis of randomized controlled trials.
    Journal of affective disorders, 2023, 10-01, Volume: 338

    Topics: Anorexia Nervosa; Antipsychotic Agents; Binge-Eating Disorder; Bulimia Nervosa; Feeding and Eating D

2023
Efficacy of pharmacotherapies for bulimia nervosa: a systematic review and meta-analysis.
    BMC pharmacology & toxicology, 2023, Dec-02, Volume: 24, Issue:1

    Topics: Bulimia; Bulimia Nervosa; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Vomiting

2023
Psychopharmacological advances in eating disorders.
    Expert review of clinical pharmacology, 2018, Volume: 11, Issue:1

    Topics: Animals; Anorexia Nervosa; Binge-Eating Disorder; Bulimia Nervosa; Drug Design; Fluoxetine; Humans;

2018
Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder.
    Expert opinion on drug safety, 2018, Volume: 17, Issue:1

    Topics: Binge-Eating Disorder; Bulimia Nervosa; Fluoxetine; Humans; Lisdexamfetamine Dimesylate; Medication

2018
Pharmacologic Treatment of Eating Disorders.
    The Psychiatric clinics of North America, 2019, Volume: 42, Issue:2

    Topics: Anorexia Nervosa; Antidepressive Agents, Second-Generation; Binge-Eating Disorder; Bulimia Nervosa;

2019
Bulimia nervosa.
    BMJ clinical evidence, 2010, Jul-19, Volume: 2010

    Topics: Administration, Oral; Bulimia; Bulimia Nervosa; Cognitive Behavioral Therapy; Evidence-Based Medicin

2010

Trials

9 trials available for fluoxetine and Bulimia Nervosa

ArticleYear
Parotid salivary parameters in bulimic patients - a controlled clinical trial.
    Psychiatria polska, 2015, Volume: 49, Issue:4

    Topics: Bulimia Nervosa; Female; Fluoxetine; Humans; Parotid Gland; Saliva; Salivary Glands; Secretory Rate;

2015
A randomized, double-blind trial comparing sertraline and fluoxetine 6-month treatment in obese patients with Binge Eating Disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Aug-01, Volume: 32, Issue:6

    Topics: Adult; Body Mass Index; Bulimia Nervosa; Double-Blind Method; Female; Fluoxetine; Humans; Middle Age

2008
Restraint, hunger, and disinhibition following treatment for binge-eating disorder.
    The International journal of eating disorders, 2009, Volume: 42, Issue:6

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Body Mass Index; Bulimia Nervosa; Cognitive B

2009
[Comparative effectiveness of mood stabilizers in the complex therapy of bulimia nervosa].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2010, Volume: 110, Issue:1

    Topics: Affect; Antidepressive Agents, Second-Generation; Antimanic Agents; Bulimia Nervosa; Carbamazepine;

2010
Stepped care and cognitive-behavioural therapy for bulimia nervosa: randomised trial.
    The British journal of psychiatry : the journal of mental science, 2011, Volume: 198, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Bulimia Nervosa; Clinical Protocols; Cognitive Beha

2011
A cost effectiveness analysis of stepped care treatment for bulimia nervosa.
    The International journal of eating disorders, 2013, Volume: 46, Issue:4

    Topics: Adult; Bulimia Nervosa; Cognitive Behavioral Therapy; Combined Modality Therapy; Cost-Benefit Analys

2013
Binge eating disorder in obesity: comparison of different therapeutic strategies.
    Eating and weight disorders : EWD, 2005, Volume: 10, Issue:3

    Topics: Adult; Aged; Body Mass Index; Bulimia Nervosa; Cognitive Behavioral Therapy; Cohort Studies; Combine

2005
Temperament and character inventory and pharmacotherapeutic outcome in bulimia nervosa.
    Eating and weight disorders : EWD, 2005, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Assertiveness; Bulimia Nervosa; Buspirone; Female; Fluoxetine; Humans; Personalit

2005
Rapid response to treatment for binge eating disorder.
    Journal of consulting and clinical psychology, 2006, Volume: 74, Issue:3

    Topics: Adolescent; Adult; Bulimia Nervosa; Cognitive Behavioral Therapy; Double-Blind Method; Female; Fluox

2006

Other Studies

3 other studies available for fluoxetine and Bulimia Nervosa

ArticleYear
['Barbie Doll Syndrome'. A case report of body dysmorphic disorder].
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2018, Volume: 32, Issue:1

    Topics: Adult; Beauty; Body Dysmorphic Disorders; Body Size; Bulimia Nervosa; Combined Modality Therapy; Dia

2018
Early response to antidepressant treatment in bulimia nervosa.
    Psychological medicine, 2010, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bulimia Nervosa; Diagnostic and Statist

2010
Fluoxetine. Bulimia nervosa: don't use.
    Prescrire international, 2006, Volume: 15, Issue:86

    Topics: Bulimia Nervosa; Clinical Trials as Topic; Contraindications; Cost-Benefit Analysis; Fluoxetine; Fra

2006