fluoxetine has been researched along with Brain Vascular Disorders in 18 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| ", 1994) we systematically collected data from 219 patients with Major Depressive Disorder during five weeks of treatment with fluoxetine (20 mg daily)." | 5.08 | Drug monitoring studies as a method of analyzing response criteria. ( Klieser, E; Lehmann, E, 1997) |
| " This paper reports the effect of fluoxetine in treating three patients with persistent emotionalism (2 cases following cerebrovascular accidents, 1 case following encephalitis)." | 3.70 | Treatment of emotionalism with fluoxetine during rehabilitation. ( Lai, JS; Tsai, WC; Wang, TG, 1998) |
| "The clinical picture is one of melancholia in 5 to 25% of cases, and of minor or masked depression (with psychomotor retardation and somatic disorders predominating) in 75 to 95% of cases." | 2.40 | [Post-cerebrovascular stroke depression]. ( Wiart, L, 1997) |
| "Depressive disorder is a common complication of stroke." | 2.38 | Depression and cerebrovascular disease. ( Fedoroff, JP; Morris, PL; Robinson, RG, 1990) |
| "Serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system." | 1.30 | Serotonin syndrome presenting with migrainelike stroke. ( Molaie, M, 1997) |
| "Fluoxetine was associated temporally with frequent short episodes of sexual excitement described by the patient as feeling like an orgasm." | 1.28 | Fluoxetine and orgasmic sexual experiences. ( Morris, PL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (88.89) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, P | 1 |
| Zhang, X | 1 |
| Lu, Y | 1 |
| Chen, C | 1 |
| Li, C | 1 |
| Zhou, M | 1 |
| Lu, Q | 1 |
| Xu, X | 1 |
| Shen, G | 1 |
| Guo, L | 1 |
| Taragano, FE | 1 |
| Bagnatti, P | 1 |
| Allegri, RF | 1 |
| Hanger, HC | 1 |
| Weinman, E | 1 |
| Ruskin, PE | 1 |
| Berthier, ML | 2 |
| Kulisevsky, J | 2 |
| Stamenkovic, M | 1 |
| Schindler, S | 1 |
| Kasper, S | 1 |
| Dam, M | 1 |
| Tonin, P | 1 |
| De Boni, A | 1 |
| Pizzolato, G | 1 |
| Casson, S | 1 |
| Ermani, M | 1 |
| Freo, U | 1 |
| Piron, L | 1 |
| Battistin, L | 1 |
| Boyeson, MG | 1 |
| Liu, CY | 1 |
| Yang, YY | 1 |
| Wang, SJ | 1 |
| Fuh, JL | 1 |
| Liu, HC | 1 |
| Lehmann, E | 1 |
| Klieser, E | 1 |
| Molaie, M | 1 |
| Wiart, L | 1 |
| Tsai, WC | 1 |
| Lai, JS | 1 |
| Wang, TG | 1 |
| Robinson, RG | 2 |
| Nahas, Z | 1 |
| Arlinghaus, KA | 1 |
| Kotrla, KJ | 1 |
| Clearman, RR | 1 |
| George, MS | 1 |
| Morris, PL | 2 |
| Fedoroff, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Depression Occurring in the Setting of Cerebrovascular Risk -- A Pilot Study[NCT00781326] | Phase 4 | 9 participants (Actual) | Interventional | 2008-08-31 | Terminated (stopped due to Final cost of study medication was significantly greater than initial estimate,) | ||
| Effects of 3 Months Daily Treatment With Selective Serotonin Reuptake Inhibitor (SSRI, Fluoxetine) on Motor Rehabilitation After Ischemic Stroke. FLAME Trial[NCT00657163] | Phase 2 | 100 participants (Anticipated) | Interventional | 2005-03-31 | Completed | ||
| Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475] | Phase 4 | 39 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Cortex Motor Function Reorganization in Stroke Patients: A Longitudinal fMRI Study[NCT04794673] | 36 participants (Actual) | Observational | 2020-01-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hamilton Depression Rating Scale (24 item) measures symptoms of major depression. We report total score which is the sum of all items. Total score range is 0 to 76 with higher scores indicating more severe depression. We reports scores at end of Phase I for subjects completing the phase. (NCT00781326)
Timeframe: End of Phase I (at 24 weeks)
| Intervention | units on a scale (Mean) |
|---|---|
| Open Label Antidepressant | 9.5 |
3 reviews available for fluoxetine and Brain Vascular Disorders
| Article | Year |
|---|---|
[Post-cerebrovascular stroke depression].
Topics: Antidepressive Agents; Cerebrovascular Disorders; Combined Modality Therapy; Depressive Disorder; El | 1997 |
Treatment issues in poststroke depression.
Topics: Activities of Daily Living; Antidepressive Agents; Cerebrovascular Disorders; Cognition Disorders; D | 1998 |
Depression and cerebrovascular disease.
Topics: Cerebrovascular Disorders; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Male; Nortr | 1990 |
4 trials available for fluoxetine and Brain Vascular Disorders
| Article | Year |
|---|---|
A double-blind, randomized clinical trial to assess the augmentation with nimodipine of antidepressant therapy in the treatment of "vascular depression".
Topics: Aged; Antidepressive Agents, Second-Generation; Argentina; Calcium Channel Blockers; Cerebrovascular | 2005 |
Poststroke depression and fluoxetine.
Topics: Cerebrovascular Disorders; Depressive Disorder; Fluoxetine; Humans; Treatment Outcome | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Drug monitoring studies as a method of analyzing response criteria.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Depres | 1997 |
11 other studies available for fluoxetine and Brain Vascular Disorders
| Article | Year |
|---|---|
Fluoxetine ameliorates cognitive impairments induced by chronic cerebral hypoperfusion via down-regulation of HCN2 surface expression in the hippocampal CA1 area in rats.
Topics: Animals; CA1 Region, Hippocampal; Carotid Stenosis; Cerebrovascular Circulation; Cerebrovascular Dis | 2016 |
Emotionalism after stroke.
Topics: Affective Symptoms; Aged; Cerebrovascular Disorders; Crying; Fluoxetine; Humans; Male | 1993 |
Anger attacks in poststroke depression: response to fluoxetine.
Topics: Anger; Cerebrovascular Disorders; Depressive Disorder; Fluoxetine; Humans; Male; Middle Aged | 1994 |
Fluoxetine--induced mania in a patient with post-stroke depression.
Topics: Bipolar Disorder; Cerebrovascular Disorders; Depressive Disorder; Female; Fluoxetine; Humans; Middle | 1993 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; C | 1996 |
Fluoxetine-related suicidality and muscle aches in a patient with poststroke depression.
Topics: Aged; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Depressive Disorder; Fluo | 1996 |
A new case of fluoxetine-induced mania in poststroke depression.
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Cerebrovascular Disorders; Depres | 1997 |
Serotonin syndrome presenting with migrainelike stroke.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Clomipramine; Confusi | 1997 |
Treatment of emotionalism with fluoxetine during rehabilitation.
Topics: Affective Symptoms; Aged; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Encep | 1998 |
Rapid response of emotional incontinence to selective serotonin reuptake inhibitors.
Topics: Adult; Affective Symptoms; Aged; Brain Injuries; Cerebrovascular Disorders; Crying; Fluoxetine; Huma | 1998 |
Fluoxetine and orgasmic sexual experiences.
Topics: Aged; Cerebrovascular Disorders; Depressive Disorder; Fluoxetine; Humans; Male; Orgasm; Sexual Behav | 1991 |