fluoxetine has been researched along with Brain Infarction in 4 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine was orally administrated starting 1 week after ischemia, with a dose of 16mg/kg/day for 3 weeks." | 5.42 | Fluoxetine enhanced neurogenesis is not translated to functional outcome in stroke rats. ( Jolkkonen, J; Liu, T; Sun, X; Xiao, T; Zhao, C; Zhao, M; Zhao, S, 2015) |
| "Fluoxetine treatment did not affect the survival or differentiation of newly generated cells in the SVZ i." | 1.43 | Fluoxetine Enhances Neurogenesis in Aged Rats with Cortical Infarcts, but This is not Reflected in a Behavioral Recovery. ( Jolkkonen, J; Liu, T; Sun, X; Xiao, T; Zhao, C; Zhao, M; Zhao, S; Zhou, Z, 2016) |
| "Fluoxetine was orally administrated starting 1 week after ischemia, with a dose of 16mg/kg/day for 3 weeks." | 1.42 | Fluoxetine enhanced neurogenesis is not translated to functional outcome in stroke rats. ( Jolkkonen, J; Liu, T; Sun, X; Xiao, T; Zhao, C; Zhao, M; Zhao, S, 2015) |
| "Fluoxetine has been given to stroke patients to combat depression but its effects on recovery of function are not known." | 1.33 | Fluoxetine and recovery of motor function after focal ischemia in rats. ( Corbett, D; Windle, V, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, X | 3 |
| Liu, T | 2 |
| Zhao, M | 2 |
| Zhao, S | 2 |
| Xiao, T | 2 |
| Jolkkonen, J | 2 |
| Zhao, C | 2 |
| Zhou, Z | 1 |
| Windle, V | 1 |
| Corbett, D | 1 |
| Pariente, J | 1 |
| Loubinoux, I | 1 |
| Carel, C | 1 |
| Albucher, JF | 1 |
| Leger, A | 1 |
| Manelfe, C | 1 |
| Rascol, O | 1 |
| Chollet, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of 3 Months Daily Treatment With Selective Serotonin Reuptake Inhibitor (SSRI, Fluoxetine) on Motor Rehabilitation After Ischemic Stroke. FLAME Trial[NCT00657163] | Phase 2 | 100 participants (Anticipated) | Interventional | 2005-03-31 | Completed | ||
| Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475] | Phase 4 | 39 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Cortex Motor Function Reorganization in Stroke Patients: A Longitudinal fMRI Study[NCT04794673] | 36 participants (Actual) | Observational | 2020-01-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluoxetine and Brain Infarction
| Article | Year |
|---|---|
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Topics: Adult; Aged; Brain; Brain Infarction; Cross-Over Studies; Double-Blind Method; Female; Fluoxetine; H | 2001 |
3 other studies available for fluoxetine and Brain Infarction
| Article | Year |
|---|---|
Fluoxetine enhanced neurogenesis is not translated to functional outcome in stroke rats.
Topics: Animals; Brain Infarction; Corpus Striatum; Dendrites; Dentate Gyrus; Fluoxetine; Ischemic Attack, T | 2015 |
Fluoxetine Enhances Neurogenesis in Aged Rats with Cortical Infarcts, but This is not Reflected in a Behavioral Recovery.
Topics: Animals; Antidepressive Agents, Second-Generation; Apoptosis; Brain Infarction; Cerebral Cortex; End | 2016 |
Fluoxetine and recovery of motor function after focal ischemia in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Fluoxetine; Male; | 2005 |