Page last updated: 2024-10-27

fluoxetine and Bradycardia

fluoxetine has been researched along with Bradycardia in 16 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
" We report a case of a possible interaction with pimozide which led to a potentially life threatening bradycardia."7.68Possible interaction between fluoxetine and pimozide causing sinus bradycardia. ( Ahmed, I; Dagincourt, PG; Miller, LG; Shader, RI, 1993)
" fluoxetine and chlorimipramine) or the 5-HT itself greatly reduced the reflex bradycardia induced by the systemically administered adrenaline."7.66Effects of 5-hydroxytryptamine, fluoxetine and chlorimipramine on reflex bradycardia in rats. ( Fan, YC; Lin, MT; Tsay, BL, 1980)
"Fluoxetine appears to cause a low incidence of adverse cardiac effects."5.28Fluoxetine-induced bradycardia and syncope in two patients. ( Ellison, JM; Ely, E; Milofsky, JE, 1990)
"Although depression and cardiovascular diseases are related, the role of antidepressants such as fluoxetine (increasing serotonin levels) within cardiac regulation remains unclear."3.91Fluoxetine oral treatment discloses 5-HT ( García-Domingo, M; García-Pedraza, JÁ; Gómez-Roso, M; López, C; Martín, ML; Morán, A, 2019)
" We report a case of a possible interaction with pimozide which led to a potentially life threatening bradycardia."3.68Possible interaction between fluoxetine and pimozide causing sinus bradycardia. ( Ahmed, I; Dagincourt, PG; Miller, LG; Shader, RI, 1993)
" fluoxetine and chlorimipramine) or the 5-HT itself greatly reduced the reflex bradycardia induced by the systemically administered adrenaline."3.66Effects of 5-hydroxytryptamine, fluoxetine and chlorimipramine on reflex bradycardia in rats. ( Fan, YC; Lin, MT; Tsay, BL, 1980)
"Fluoxetine appears to cause a low incidence of adverse cardiac effects."1.28Fluoxetine-induced bradycardia and syncope in two patients. ( Ellison, JM; Ely, E; Milofsky, JE, 1990)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's13 (81.25)18.2507
2000's1 (6.25)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
López, C1
Gómez-Roso, M1
García-Pedraza, JÁ1
Martín, ML1
Morán, A1
García-Domingo, M1
Compton, R1
Spiller, HA1
Bosse, GM1
Lin, MT1
Tsay, BL1
Fan, YC1
Grubb, BP1
Wolfe, DA1
Samoil, D1
Temesy-Armos, P1
Hahn, H1
Elliott, L1
Friedman, EH3
Edleman, RJ1
Pfeffer, CR1
Ehlers, KH1
Hussein, S1
Kaufman, BM1
Ahmed, I1
Dagincourt, PG1
Miller, LG1
Shader, RI1
Masquelier, I1
Saint Jean, O1
Bourdiol, MC1
Boiffin, A1
Bouchon, JP1
Anderson, J1
Compton, SA1
Rich, JM1
Njo, L1
Roberts, KW1
Smith, KP1
Feder, R1
Buff, DD1
Brenner, R1
Kirtane, SS1
Gilboa, R1
Ellison, JM1
Milofsky, JE1
Ely, E1

Other Studies

16 other studies available for fluoxetine and Bradycardia

ArticleYear
Fluoxetine oral treatment discloses 5-HT
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:2

    Topics: Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Bradycardia; Depression; Di

2019
Fatal fluoxetine ingestion with postmortem blood concentrations.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bradycardia; Child, Preschool; Dia

2005
Effects of 5-hydroxytryptamine, fluoxetine and chlorimipramine on reflex bradycardia in rats.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:7

    Topics: Animals; Blood Pressure; Bradycardia; Brain; Clomipramine; Dose-Response Relationship, Drug; Epineph

1980
Usefulness of fluoxetine hydrochloride for prevention of resistant upright tilt induced syncope.
    Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:3 Pt 1

    Topics: Adult; Bradycardia; Drug Tolerance; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Male; Post

1993
Re: Bradycardia and somnolence after adding fluoxetine to pimozide regimen.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:10

    Topics: Aged; Bradycardia; Brain Stem; Cerebral Cortex; Dementia; Dominance, Cerebral; Drug Synergism; Fluox

1994
Cardiac effects and fluoxetine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:4

    Topics: Bradycardia; Child; Depressive Disorder; Electrocardiography, Ambulatory; Fluoxetine; Humans; Male;

1994
Bradycardia associated with fluoxetine in an elderly patient with sick sinus syndrome.
    Postgraduate medical journal, 1994, Volume: 70, Issue:819

    Topics: Aged; Aged, 80 and over; Bradycardia; Female; Fluoxetine; Humans; Sick Sinus Syndrome

1994
Possible interaction between fluoxetine and pimozide causing sinus bradycardia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:1

    Topics: Aged; Arrhythmia, Sinus; Bradycardia; Delusions; Dementia; Depressive Disorder; Dose-Response Relati

1993
[Bradycardia and hypothermia in an elderly patient receiving fluoxetine].
    Presse medicale (Paris, France : 1983), 1993, Mar-27, Volume: 22, Issue:11

    Topics: Bradycardia; Female; Fluoxetine; Humans; Hypothermia; Middle Aged

1993
Fluoxetine induced bradycardia in presenile dementia.
    The Ulster medical journal, 1997, Volume: 66, Issue:2

    Topics: Aged; Alzheimer Disease; Antidepressive Agents, Second-Generation; Bradycardia; Dementia; Fluoxetine

1997
Unusual hypotension and bradycardia in a patient receiving fenfluramine, phentermine, and fluoxetine.
    Anesthesiology, 1998, Volume: 88, Issue:2

    Topics: Anesthesia, Conduction; Anesthetics, Intravenous; Appetite Depressants; Bradycardia; Drug Interactio

1998
Fluoxetine-induced bradycardia.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Atrial Fibrillation; Bradycardia; Female; Fluoxetine; Humans;

1991
The role of the right hemisphere in fluoxetine-induced bradycardia and syncope.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:3

    Topics: Bradycardia; Brain; Female; Fluoxetine; Functional Laterality; Humans; Sex Factors; Syncope

1991
Bradycardia and syncope induced by fluoxetine.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:3

    Topics: Adult; Blood Pressure; Bradycardia; Depressive Disorder; Dose-Response Relationship, Drug; Female; F

1991
Dysrhythmia associated with fluoxetine treatment in an elderly patient with cardiac disease.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Atrial Fibrillation; Bradycardia; Depressive Disorder; Female;

1991
Fluoxetine-induced bradycardia and syncope in two patients.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:9

    Topics: Adult; Bradycardia; Depressive Disorder; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Synco

1990