Page last updated: 2024-10-27

fluoxetine and Binge-Eating Disorder

fluoxetine has been researched along with Binge-Eating Disorder in 8 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Binge-Eating Disorder: A disorder associated with three or more of the following: eating until feeling uncomfortably full; eating large amounts of food when not physically hungry; eating much more rapidly than normal; eating alone due to embarrassment; feeling of disgust, DEPRESSION, or guilt after overeating. Criteria includes occurrence on average, at least 2 days a week for 6 months. The binge eating is not associated with the regular use of inappropriate compensatory behavior (i.e. purging, excessive exercise, etc.) and does not co-occur exclusively with BULIMIA NERVOSA or ANOREXIA NERVOSA. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
" Antidepressants are commonly used to treat bulimia nervosa; high-dose fluoxetine is a standard approach, but many other antidepressants can be used."5.01Pharmacologic Treatment of Eating Disorders. ( Crow, SJ, 2019)
"This study aimed to evaluate whether genetic reductions in brain serotonin influence binge eating and/or the ability of fluoxetine, a selective serotonin reuptake inhibitor, to reduce binge eating in mice."4.12Brain serotonin deficiency and fluoxetine lead to sex-specific effects on binge-like food consumption in mice. ( Baugher, BJ; Huq, SN; Karth, MD; Karth, MM; Pellechia, SA; Sachs, BD; Warner, AK, 2022)
"Fluoxetine for BN and lisdexamfetamine for BED are relatively safe and well-tolerated."2.58Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder. ( Bello, NT; Yeomans, BL, 2018)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Karth, MD1
Baugher, BJ1
Pellechia, SA1
Huq, SN1
Warner, AK1
Karth, MM1
Sachs, BD1
Fornaro, M1
Mondin, AM1
Billeci, M1
Fusco, A1
De Prisco, M1
Caiazza, C1
Micanti, F1
Calati, R1
Carvalho, AF1
de Bartolomeis, A1
Himmerich, H1
Treasure, J1
Bello, NT1
Yeomans, BL1
Crow, SJ1
Czyzyk, TA1
Sahr, AE1
Statnick, MA1
Grilo, CM2
Masheb, RM2
Crosby, RD2
Wilson, GT1

Reviews

4 reviews available for fluoxetine and Binge-Eating Disorder

ArticleYear
Psychopharmacology of eating disorders: Systematic review and meta-analysis of randomized controlled trials.
    Journal of affective disorders, 2023, 10-01, Volume: 338

    Topics: Anorexia Nervosa; Antipsychotic Agents; Binge-Eating Disorder; Bulimia Nervosa; Feeding and Eating D

2023
Psychopharmacological advances in eating disorders.
    Expert review of clinical pharmacology, 2018, Volume: 11, Issue:1

    Topics: Animals; Anorexia Nervosa; Binge-Eating Disorder; Bulimia Nervosa; Drug Design; Fluoxetine; Humans;

2018
Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder.
    Expert opinion on drug safety, 2018, Volume: 17, Issue:1

    Topics: Binge-Eating Disorder; Bulimia Nervosa; Fluoxetine; Humans; Lisdexamfetamine Dimesylate; Medication

2018
Pharmacologic Treatment of Eating Disorders.
    The Psychiatric clinics of North America, 2019, Volume: 42, Issue:2

    Topics: Anorexia Nervosa; Antidepressive Agents, Second-Generation; Binge-Eating Disorder; Bulimia Nervosa;

2019

Trials

2 trials available for fluoxetine and Binge-Eating Disorder

ArticleYear
Predictors and moderators of response to cognitive behavioral therapy and medication for the treatment of binge eating disorder.
    Journal of consulting and clinical psychology, 2012, Volume: 80, Issue:5

    Topics: Adolescent; Adult; Affect; Binge-Eating Disorder; Body Image; Body Mass Index; Cognitive Behavioral

2012
12-month follow-up of fluoxetine and cognitive behavioral therapy for binge eating disorder.
    Journal of consulting and clinical psychology, 2012, Volume: 80, Issue:6

    Topics: Adolescent; Adult; Binge-Eating Disorder; Cognitive Behavioral Therapy; Combined Modality Therapy; D

2012

Other Studies

2 other studies available for fluoxetine and Binge-Eating Disorder

ArticleYear
Brain serotonin deficiency and fluoxetine lead to sex-specific effects on binge-like food consumption in mice.
    Psychopharmacology, 2022, Volume: 239, Issue:9

    Topics: Animals; Binge-Eating Disorder; Brain; Bulimia; Female; Fluoxetine; Male; Mice; Serotonin

2022
A model of binge-like eating behavior in mice that does not require food deprivation or stress.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:9

    Topics: Adiposity; Animals; Anti-Obesity Agents; Baclofen; Behavior, Animal; Binge-Eating Disorder; Body Wei

2010