Page last updated: 2024-10-27

fluoxetine and Benign Neoplasms

fluoxetine has been researched along with Benign Neoplasms in 22 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine has shown superior efficacy compared with placebo in the treatment of depression in patients with HIV/AIDS, diabetes mellitus or stroke; however, it has not significantly improved depressive symptoms versus placebo in patients with cancer."8.81Fluoxetine: a review of its therapeutic potential in the treatment of depression associated with physical illness. ( Cheer, SM; Goa, KL, 2001)
"To observe the depression in patients with malignant tumor and influencing factors of the disease, as well as to investigate the effects of fluoxetine on depressive symptoms in cancer patients and the immune function."7.85Study of prevalence and influencing factors of depression in tumor patients and the therapeutic effects of fluoxetine. ( Dai, J; Liao, N; Shi, J; Tao, JQ, 2017)
"Helping oncologists to identify and treat depression is an important step in improving the overall care of people with cancer."5.31Use of a depression screening tool and a fluoxetine-based algorithm to improve the recognition and treatment of depression in cancer patients. A demonstration project. ( Donaghy, K; Dugan, W; Edgerton, S; Holtsclaw, E; Kirsh, KL; Passik, SD; Theobald, D, 2002)
"To determine whether fluoxetine improves overall quality of life (QOL) in advanced cancer patients with symptoms of depression revealed by a simple survey."5.10Fluoxetine versus placebo in advanced cancer outpatients: a double-blinded trial of the Hoosier Oncology Group. ( Arquette, MA; Brames, MJ; Einhorn, LH; Fisch, MJ; Jung, SH; Kristeller, J; Loehrer, PJ; Passik, S; Shen, J, 2003)
"Fluoxetine has shown superior efficacy compared with placebo in the treatment of depression in patients with HIV/AIDS, diabetes mellitus or stroke; however, it has not significantly improved depressive symptoms versus placebo in patients with cancer."4.81Fluoxetine: a review of its therapeutic potential in the treatment of depression associated with physical illness. ( Cheer, SM; Goa, KL, 2001)
"To observe the depression in patients with malignant tumor and influencing factors of the disease, as well as to investigate the effects of fluoxetine on depressive symptoms in cancer patients and the immune function."3.85Study of prevalence and influencing factors of depression in tumor patients and the therapeutic effects of fluoxetine. ( Dai, J; Liao, N; Shi, J; Tao, JQ, 2017)
"Of 115 cancer patients who fulfilled entry criteria for levels of distress, 45 patients were randomized to a fluoxetine treatment group (FA) and 46 patients to a placebo group (PA) after a 1-week placebo period designed to exclude placebo responders."2.68The effect of fluoxetine on anxiety and depression symptoms in cancer patients. ( Allilaire, JF; Blin, P; Bouhassira, M; Cordier, B; Desclaux, B; Fresco, R; Gauvain-Piquard, A; Guillibert, E; Mesters, P; Orth, JP; Piollet, I; Razavi, D; Salimpour, A; Saltel, P; Sechter, D; Smith, M; Trichard, C; Verra, M, 1996)
"Thus, one way to view cancer is within systems biology as a network disorder affecting the ability of cells to properly interact with a morphodynamic field of instructive signals that keeps proliferation and migration orchestrated toward the anatomical needs of the host organism."2.55Ion Channel and Neurotransmitter Modulators as Electroceutical Approaches to the Control of Cancer. ( Levin, M; Tilli, TM; Tuszynski, J, 2017)
"The possible anticancer activity of combination (M + E + F) of metformin (M), efavirenz (E), and fluoxetine (F) was investigated in normal HDF cells and HCT116 human colon cancer cells."1.91Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification. ( Feng, JH; Inci, G; Jung, JS; Kang, BG; Kim, JH; Kim, SB; Kim, SC; Lee, JY; Lim, SS; Mo, YW; Park, SH; Seo, JH; Shende, M; Suh, HW, 2023)
"Trazodone is a unique antidepressant, which blocks the postsynaptic serotonin (5-HT) receptors, 5-HT(2A) and 5-HT(2C), and weakly inhibits presynaptic 5-HT transporters."1.34Does trazodone have a role in palliating symptoms? ( Davis, MP, 2007)
"Helping oncologists to identify and treat depression is an important step in improving the overall care of people with cancer."1.31Use of a depression screening tool and a fluoxetine-based algorithm to improve the recognition and treatment of depression in cancer patients. A demonstration project. ( Donaghy, K; Dugan, W; Edgerton, S; Holtsclaw, E; Kirsh, KL; Passik, SD; Theobald, D, 2002)
"Fluoxetine (Prozac) is an effective and increasingly widely used antidepressant."1.29Fluoxetine treatment comprises the antiemetic efficacy of ondansetron in cancer patients. ( Koriech, OM, 1995)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (36.36)18.2507
2000's7 (31.82)29.6817
2010's5 (22.73)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH2
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Kang, BG1
Shende, M1
Inci, G1
Park, SH1
Jung, JS1
Kim, SB1
Kim, JH1
Mo, YW1
Feng, JH1
Kim, SC1
Lim, SS1
Suh, HW1
Lee, JY1
He, S1
Moutaoufik, MT1
Islam, S1
Persad, A1
Wu, A1
Aly, KA1
Fonge, H1
Babu, M1
Cayabyab, FS1
Tuszynski, J1
Tilli, TM1
Levin, M1
Dai, J1
Liao, N1
Shi, J1
Tao, JQ1
Zhu, L1
Ploessl, K1
Kung, HF1
Labos, C1
Dasgupta, K1
Nedjar, H1
Turecki, G1
Rahme, E1
Passik, SD1
Kirsh, KL1
Theobald, D1
Donaghy, K1
Holtsclaw, E1
Edgerton, S1
Dugan, W1
Fisch, MJ1
Loehrer, PJ1
Kristeller, J1
Passik, S1
Jung, SH1
Shen, J1
Arquette, MA1
Brames, MJ1
Einhorn, LH1
Alliot, C1
Coyne, JC1
Palmer, SC1
Shapiro, PJ1
Davis, MP1
Mathews, J1
Pande, AC1
Miller, LG1
Koriech, OM1
Storch, DD1
Razavi, D1
Allilaire, JF1
Smith, M1
Salimpour, A1
Verra, M1
Desclaux, B1
Saltel, P1
Piollet, I1
Gauvain-Piquard, A1
Trichard, C1
Cordier, B1
Fresco, R1
Guillibert, E1
Sechter, D1
Orth, JP1
Bouhassira, M1
Mesters, P1
Blin, P1
Henney, JE1
Cheer, SM1
Goa, KL1
Shuster, JL1
Stern, TA1
Greenberg, DB1
Viswanathan, R1
Paradis, C1

Reviews

5 reviews available for fluoxetine and Benign Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
HERG channel and cancer: A mechanistic review of carcinogenic processes and therapeutic potential.
    Biochimica et biophysica acta. Reviews on cancer, 2020, Volume: 1873, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Carcinogenesis; Cell Movement; Cell Proliferation;

2020
Ion Channel and Neurotransmitter Modulators as Electroceutical Approaches to the Control of Cancer.
    Current pharmaceutical design, 2017, Volume: 23, Issue:32

    Topics: Animals; Antineoplastic Agents; Bioelectric Energy Sources; Cell Proliferation; Cell Survival; Fluox

2017
Fluoxetine: a review of its therapeutic potential in the treatment of depression associated with physical illness.
    Drugs, 2001, Volume: 61, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antidepressive Agents; Clinical Trials as Topic; Cytochrome P-45

2001
Pros and cons of fluoxetine for the depressed cancer patient.
    Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:11

    Topics: Antidepressive Agents; Depression; Fluoxetine; Half-Life; Humans; Neoplasms

1992

Trials

2 trials available for fluoxetine and Benign Neoplasms

ArticleYear
Fluoxetine versus placebo in advanced cancer outpatients: a double-blinded trial of the Hoosier Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-15, Volume: 21, Issue:10

    Topics: Ambulatory Care; Antidepressive Agents, Second-Generation; Depression; Double-Blind Method; Female;

2003
The effect of fluoxetine on anxiety and depression symptoms in cancer patients.
    Acta psychiatrica Scandinavica, 1996, Volume: 94, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety Disorders; Depressive Disorder; Doubl

1996

Other Studies

15 other studies available for fluoxetine and Benign Neoplasms

ArticleYear
Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification.
    Cancer biology & therapy, 2023, 12-31, Volume: 24, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Line, Tumor; Fluoxetine; HCT116 Cells; Human

2023
Study of prevalence and influencing factors of depression in tumor patients and the therapeutic effects of fluoxetine.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:21

    Topics: Aged; Antidepressive Agents, Second-Generation; Depression; Female; Fluoxetine; Humans; Killer Cells

2017
Chemistry. Expanding the scope of fluorine tags for PET imaging.
    Science (New York, N.Y.), 2013, Oct-25, Volume: 342, Issue:6157

    Topics: Alzheimer Disease; Aniline Compounds; Celecoxib; Ethylene Glycols; Fluorescent Dyes; Fluorine Radioi

2013
Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Nov-08, Volume: 183, Issue:16

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Angioplasty; Anticoagulants; Antihypertensive Ag

2011
Use of a depression screening tool and a fluoxetine-based algorithm to improve the recognition and treatment of depression in cancer patients. A demonstration project.
    Journal of pain and symptom management, 2002, Volume: 24, Issue:3

    Topics: Algorithms; Antidepressive Agents, Second-Generation; Depression; Female; Fluoxetine; Humans; Male;

2002
Fluoxetine versus placebo in advanced cancer outpatients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jan-01, Volume: 22, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Depression; Drug Interactions; Fluoxetine; Humans; Neoplas

2004
Prescribing antidepressants to advanced cancer patients with mild depressive symptoms is not justified.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jan-01, Volume: 22, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Clinical Trials as Topic; Depressive Disorder; Fluoxetine;

2004
Does trazodone have a role in palliating symptoms?
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007, Volume: 15, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Depression; Drug Interactions; Fluoxetine; Humans; Neoplas

2007
Concern over Prozac-induced tumor growth may dwindle following FDA study.
    Journal of the National Cancer Institute, 1995, Sep-06, Volume: 87, Issue:17

    Topics: Amitriptyline; Animals; Depression; Fluoxetine; Humans; Loratadine; Neoplasms; Recurrence; United St

1995
Response to "Antidepressants and cancer: cause for concern?".
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:6

    Topics: Animals; Fluoxetine; Humans; Mice; Neoplasms; Rats

1993
Antidepressants and cancer: cause for concern?
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cocarcinogenesis; Depressive Disorder; Fluoxetine; Hu

1993
Fluoxetine treatment comprises the antiemetic efficacy of ondansetron in cancer patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1995, Volume: 7, Issue:6

    Topics: Adult; Antiemetics; Binding, Competitive; Female; Fluoxetine; Humans; Male; Middle Aged; Neoplasms;

1995
Do antidepressants promote tumor growth?
    The American journal of psychiatry, 1996, Volume: 153, Issue:3

    Topics: Animals; Antidepressive Agents; Carcinogens; Depressive Disorder; Fluoxetine; Humans; Neoplasms; Sel

1996
From the Food and Drug Administration.
    JAMA, 2000, Sep-13, Volume: 284, Issue:10

    Topics: Administration, Oral; Antiviral Agents; Cyclosporine; Drug and Narcotic Control; Drug Labeling; Fluo

2000
Treatment of cancer phobia with fluoxetine.
    The American journal of psychiatry, 1991, Volume: 148, Issue:8

    Topics: Adult; Female; Fluoxetine; Humans; Hypochondriasis; Neoplasms; Obsessive-Compulsive Disorder

1991