fluoxetine has been researched along with Benign Neoplasms, Brain in 13 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use." | 7.83 | Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. ( Chen, MH; Chen, W; Ma, J; Sun, LL; Wang, DC; Wang, FZ; Wang, H; Wang, XD; Yang, YR, 2016) |
| "We studied the effect of fluoxetine, an SSRI, on the development of brain metastatic breast cancer using MDA-MB-231BR cells in a mouse model." | 7.80 | Fluoxetine modulates breast cancer metastasis to the brain in a murine model. ( Amico-Ruvio, SA; Brown, EB; Dickerson, IM; Kelly, EA; Majewska, AK; Shapovalov, Y; Sipe, GO; Spielman, SC; Zettel, M, 2014) |
| "In C6 glioma cells, we studied acute administration of SSRI antidepressants - fluoxetine, sertraline and citalopram." | 7.78 | Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells. ( Kováru, F; Kovárů, H; Lisá, V, 2012) |
| "We studied the effect of acute administration of fluoxetine or NECA agonist of adenosine receptor (GPCR) on C6 glioma cells and natural killer (NK) cell line, innate immunity." | 7.77 | Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes. ( Fiserová, A; Kovaru, F; Kovárů, H; Lisá, V; Ondráčkova, P, 2011) |
| " However, vital safety and efficacy issues related to combined therapy with temozolomide, the first-line cytostatic in patients diagnosed with glioblastoma multiforme, and antidepressant drugs have yet to be addressed." | 3.85 | Antidepressant drugs can modify cytotoxic action of temozolomide. ( Bielecka, AM; Obuchowicz, E, 2017) |
| "Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use." | 3.83 | Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. ( Chen, MH; Chen, W; Ma, J; Sun, LL; Wang, DC; Wang, FZ; Wang, H; Wang, XD; Yang, YR, 2016) |
| "We studied the effect of fluoxetine, an SSRI, on the development of brain metastatic breast cancer using MDA-MB-231BR cells in a mouse model." | 3.80 | Fluoxetine modulates breast cancer metastasis to the brain in a murine model. ( Amico-Ruvio, SA; Brown, EB; Dickerson, IM; Kelly, EA; Majewska, AK; Shapovalov, Y; Sipe, GO; Spielman, SC; Zettel, M, 2014) |
| "In C6 glioma cells, we studied acute administration of SSRI antidepressants - fluoxetine, sertraline and citalopram." | 3.78 | Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells. ( Kováru, F; Kovárů, H; Lisá, V, 2012) |
| "We studied the effect of acute administration of fluoxetine or NECA agonist of adenosine receptor (GPCR) on C6 glioma cells and natural killer (NK) cell line, innate immunity." | 3.77 | Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes. ( Fiserová, A; Kovaru, F; Kovárů, H; Lisá, V; Ondráčkova, P, 2011) |
| "The highly lethal brain cancer glioblastoma (GBM) poses a daunting challenge because the blood-brain barrier renders potentially druggable amplified or mutated oncoproteins relatively inaccessible." | 1.62 | Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. ( Armando, AM; Bi, J; Cloughesy, TF; Cravatt, BF; Curtis, EJ; Furnari, FB; Gimple, RC; Gu, Y; Jing, H; Khan, A; Koga, T; Kornblum, HI; Miki, S; Mischel, PS; Prager, B; Quehenberger, O; Reed, A; Rich, JN; Rzhetsky, A; Tang, J; Wainwright, DA; Wong, IT; Wu, S; Yang, H; Zhang, W, 2021) |
| "Management and resolution of the hydrocephalus was temporally associated with an improvement in his OCD compulsion symptoms." | 1.43 | Pediatric Obsessive-Compulsive Disorder Exacerbation and Obstructive Hydrocephalus: A Case Report. ( Bleakley, C; Leung, A; Loh, A; Saran, K; Stewart, SE, 2016) |
| "Temozolomide (TMZ) is a cytotoxic agent of the imidazotetrazine class, chemically related to dacarbazine." | 1.35 | Tuberculosis in a patient on temozolomide: a case report. ( de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bi, J | 1 |
| Khan, A | 1 |
| Tang, J | 1 |
| Armando, AM | 1 |
| Wu, S | 1 |
| Zhang, W | 1 |
| Gimple, RC | 1 |
| Reed, A | 1 |
| Jing, H | 1 |
| Koga, T | 1 |
| Wong, IT | 1 |
| Gu, Y | 1 |
| Miki, S | 1 |
| Yang, H | 1 |
| Prager, B | 1 |
| Curtis, EJ | 1 |
| Wainwright, DA | 1 |
| Furnari, FB | 1 |
| Rich, JN | 1 |
| Cloughesy, TF | 1 |
| Kornblum, HI | 1 |
| Quehenberger, O | 1 |
| Rzhetsky, A | 1 |
| Cravatt, BF | 1 |
| Mischel, PS | 1 |
| Radin, DP | 1 |
| Purcell, R | 1 |
| Lippa, AS | 1 |
| Narasimha, VL | 1 |
| Basavaraju, R | 1 |
| Mangalore, S | 1 |
| Mehta, UM | 1 |
| Shapovalov, Y | 1 |
| Zettel, M | 1 |
| Spielman, SC | 1 |
| Amico-Ruvio, SA | 1 |
| Kelly, EA | 1 |
| Sipe, GO | 1 |
| Dickerson, IM | 1 |
| Majewska, AK | 1 |
| Brown, EB | 1 |
| Liu, KH | 1 |
| Yang, ST | 1 |
| Lin, YK | 1 |
| Lin, JW | 1 |
| Lee, YH | 1 |
| Wang, JY | 1 |
| Hu, CJ | 1 |
| Lin, EY | 1 |
| Chen, SM | 1 |
| Then, CK | 1 |
| Shen, SC | 1 |
| Ma, J | 1 |
| Yang, YR | 1 |
| Chen, W | 1 |
| Chen, MH | 1 |
| Wang, H | 1 |
| Wang, XD | 1 |
| Sun, LL | 1 |
| Wang, FZ | 1 |
| Wang, DC | 1 |
| Bielecka, AM | 1 |
| Obuchowicz, E | 1 |
| Leung, A | 1 |
| Bleakley, C | 1 |
| Loh, A | 1 |
| Saran, K | 1 |
| Stewart, SE | 1 |
| de Paiva, TF | 1 |
| de Barros e Silva, MJ | 1 |
| Rinck, JA | 1 |
| Fanelli, MF | 1 |
| Gimenes, DL | 1 |
| Kovárů, H | 2 |
| Kovaru, F | 2 |
| Ondráčkova, P | 1 |
| Lisá, V | 2 |
| Fiserová, A | 1 |
| Komlósi, G | 1 |
| Molnár, G | 1 |
| Rózsa, M | 1 |
| Oláh, S | 1 |
| Barzó, P | 1 |
| Tamás, G | 1 |
| Sokol, MS | 1 |
| Fujimoto, CK | 1 |
| Jackson, TK | 1 |
| Silberberg, PJ | 1 |
13 other studies available for fluoxetine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; | 2021 |
Oncolytic Properties of Ampakines
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Fluoxetine; Glioblastoma; H | 2018 |
Precuneus and psychiatric manifestations: Novel neurobiological formulations through lesion based connectivity mapping of psychopathology.
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain Mapping; Brai | 2019 |
Fluoxetine modulates breast cancer metastasis to the brain in a murine model.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Proliferatio | 2014 |
Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis.
Topics: Animals; Antidepressive Agents, Second-Generation; Apoptosis; Brain Neoplasms; Calcium; Cell Surviva | 2015 |
Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Prolif | 2016 |
Antidepressant drugs can modify cytotoxic action of temozolomide.
Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; | 2017 |
Pediatric Obsessive-Compulsive Disorder Exacerbation and Obstructive Hydrocephalus: A Case Report.
Topics: Brain Neoplasms; Child; Fluoxetine; Glioma; Humans; Hydrocephalus; Male; Obsessive-Compulsive Disord | 2016 |
Tuberculosis in a patient on temozolomide: a case report.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Ant | 2009 |
Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents, Tricyclic; Brain Neoplasms; Cell | 2011 |
Fluoxetine (prozac) and serotonin act on excitatory synaptic transmission to suppress single layer 2/3 pyramidal neuron-triggered cell assemblies in the human prefrontal cortex.
Topics: Adult; Aged; Brain Neoplasms; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Female; Fl | 2012 |
Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Neoplasms; Cell Line, Tumor; Citalopram; Depressio | 2012 |
Anorexia nervosa and brain tumor in a 14-year-old girl.
Topics: Adolescent; Anorexia Nervosa; Brain Neoplasms; Depression; Female; Fluoxetine; Humans; Magnetic Reso | 2006 |