fluoxetine has been researched along with Autism Spectrum Disorder in 22 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the efficacy of fluoxetine for reducing the frequency and severity of obsessive-compulsive behaviors in autism spectrum disorders." | 9.30 | Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial. ( Dossetor, D; Granich, J; Hazell, P; Kohn, M; Lee, KJ; Marraffa, C; Mouti, A; O'Sullivan, M; Orsini, F; Reddihough, DS; Santosh, P; Silove, N; Whitehouse, AJO; Wray, J, 2019) |
| "To determine the efficacy of fluoxetine for reducing the frequency and severity of obsessive-compulsive behaviors in autism spectrum disorders." | 5.30 | Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial. ( Dossetor, D; Granich, J; Hazell, P; Kohn, M; Lee, KJ; Marraffa, C; Mouti, A; O'Sullivan, M; Orsini, F; Reddihough, DS; Santosh, P; Silove, N; Whitehouse, AJO; Wray, J, 2019) |
| "Autism spectrum disorders are a group of neurodevelopmental disorders characterized by impaired verbal and/or nonverbal communication in addition to repeti- tive stereotypical behaviors." | 2.53 | AUTISM IN REVIEW. ( Boustany, RM; Khalifeh, S; Kourtian, S; Yassin, W, 2016) |
| "A majority of cases of idiopathic autism in children likely result from unknown environmental triggers in genetically susceptible individuals." | 1.46 | Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations. ( Kaushik, G; Pfau, JC; Thomas, MA; Xia, Y, 2017) |
| "Fluoxetine 5 mg/day was started and gradually increased to 20 mg/day." | 1.43 | Diagnosis and treatment of obsessive compulsive behavior in a boy with Duchenne muscular dystrophy and autism spectrum disorder: A case report. ( Collin, P; Hendriksen, JG; Klinkenberg, S; Niks, EH; Vles, JS; Wong, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 8 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Leussis, MP | 1 |
| Thanos, JM | 1 |
| Powers, A | 1 |
| Peterson, E | 1 |
| Head, JP | 1 |
| McGovern, NJ | 1 |
| Malarkey, FJ | 1 |
| Drake, A | 1 |
| Baribeau, D | 1 |
| Vorstman, J | 1 |
| Anagnostou, E | 1 |
| Arzuaga, AL | 1 |
| Edmison, DD | 1 |
| Mroczek, J | 1 |
| Larson, J | 1 |
| Ragozzino, ME | 1 |
| Gioia, R | 1 |
| Seri, T | 1 |
| Diamanti, T | 1 |
| Fimmanò, S | 1 |
| Vitale, M | 1 |
| Ahlenius, H | 1 |
| Kokaia, Z | 1 |
| Tirone, F | 1 |
| Micheli, L | 1 |
| Biagioni, S | 1 |
| Lupo, G | 1 |
| Rinaldi, A | 1 |
| De Jaco, A | 1 |
| Cacci, E | 1 |
| Arora, A | 1 |
| Becker, M | 1 |
| Marques, C | 1 |
| Oksanen, M | 1 |
| Li, D | 1 |
| Mastropasqua, F | 1 |
| Watts, ME | 1 |
| Arora, M | 1 |
| Falk, A | 1 |
| Daub, CO | 1 |
| Lanekoff, I | 1 |
| Tammimies, K | 1 |
| King, BH | 1 |
| Reddihough, DS | 1 |
| Marraffa, C | 1 |
| Mouti, A | 1 |
| O'Sullivan, M | 1 |
| Lee, KJ | 1 |
| Orsini, F | 1 |
| Hazell, P | 1 |
| Granich, J | 1 |
| Whitehouse, AJO | 1 |
| Wray, J | 1 |
| Dossetor, D | 1 |
| Santosh, P | 2 |
| Silove, N | 1 |
| Kohn, M | 1 |
| Ne'eman, A | 1 |
| Albrecht, K | 1 |
| Kapp, SK | 1 |
| Qiu, W | 1 |
| Go, KA | 1 |
| Wen, Y | 1 |
| Duarte-Guterman, P | 1 |
| Eid, RS | 1 |
| Galea, LAM | 1 |
| Kaushik, G | 1 |
| Xia, Y | 1 |
| Pfau, JC | 1 |
| Thomas, MA | 1 |
| Çelikkol, Ç | 1 |
| Bilgiç, A | 1 |
| Payet, JM | 1 |
| Burnie, E | 1 |
| Sathananthan, NJ | 1 |
| Russo, AM | 1 |
| Lawther, AJ | 1 |
| Kent, S | 1 |
| Lowry, CA | 1 |
| Hale, MW | 1 |
| Valaparla, VL | 1 |
| Sahoo, S | 1 |
| Padhy, SK | 1 |
| Lupu, D | 1 |
| Varshney, MK | 1 |
| Mucs, D | 1 |
| Inzunza, J | 1 |
| Norinder, U | 1 |
| Loghin, F | 1 |
| Nalvarte, I | 1 |
| Rüegg, J | 1 |
| Tu, Z | 1 |
| Zhao, H | 1 |
| Li, B | 1 |
| Yan, S | 1 |
| Wang, L | 1 |
| Tang, Y | 1 |
| Li, Z | 1 |
| Bai, D | 1 |
| Li, C | 1 |
| Lin, Y | 1 |
| Li, Y | 1 |
| Liu, J | 1 |
| Xu, H | 1 |
| Guo, X | 1 |
| Jiang, YH | 1 |
| Zhang, YQ | 1 |
| Li, XJ | 1 |
| Khalifeh, S | 1 |
| Yassin, W | 1 |
| Kourtian, S | 1 |
| Boustany, RM | 1 |
| Bond, CM | 1 |
| Johnson, JC | 1 |
| Chaudhary, V | 1 |
| McCarthy, EM | 1 |
| McWhorter, ML | 1 |
| Woehrle, NS | 1 |
| Thorkelson, G | 1 |
| Laughlin, SF | 1 |
| Turner, KS | 1 |
| Ober, N | 1 |
| Handen, BL | 1 |
| Chantiluke, K | 2 |
| Barrett, N | 2 |
| Giampietro, V | 2 |
| Brammer, M | 2 |
| Simmons, A | 2 |
| Rubia, K | 2 |
| Murphy, DG | 1 |
| Cawkwell, P | 1 |
| Lawler, A | 1 |
| Maneta, E | 1 |
| Coffey, BJ | 1 |
| Hendriksen, JG | 1 |
| Klinkenberg, S | 1 |
| Collin, P | 1 |
| Wong, B | 1 |
| Niks, EH | 1 |
| Vles, JS | 1 |
3 reviews available for fluoxetine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Novel treatments in autism spectrum disorder.
Topics: Autism Spectrum Disorder; Cannabinoids; Communication; Fluoxetine; Humans; Multicenter Studies as To | 2022 |
AUTISM IN REVIEW.
Topics: Aripiprazole; Autism Spectrum Disorder; Central Nervous System Agents; Diagnostic and Statistical Ma | 2016 |
Selective Serotonin Reuptake Inhibitor Monotherapy for Anxiety Disorders in Children and Adolescents with Autism Spectrum Disorder: A Chart Review.
Topics: Adolescent; Anxiety Disorders; Autism Spectrum Disorder; Citalopram; Comorbidity; Female; Fluoxetine | 2019 |
3 trials available for fluoxetine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial.
Topics: Adolescent; Anxiety; Autism Spectrum Disorder; Child; Confounding Factors, Epidemiologic; Female; Fl | 2019 |
Disorder-dissociated effects of fluoxetine on brain function of working memory in attention deficit hyperactivity disorder and autism spectrum disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; Double-B | 2015 |
Inverse fluoxetine effects on inhibitory brain activation in non-comorbid boys with ADHD and with ASD.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Attention Deficit Disorder with Hyperactivity; | 2015 |
16 other studies available for fluoxetine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Sex differences in long-term behavioral alterations, especially anxiety, following prenatal fluoxetine exposure in C57BL/6 mice.
Topics: Animals; Anxiety; Autism Spectrum Disorder; Behavior, Animal; Communication; Depression; Female; Flu | 2021 |
Prenatal stress and fluoxetine exposure in mice differentially affect repetitive behaviors and synaptic plasticity in adult male and female offspring.
Topics: Animals; Autism Spectrum Disorder; Female; Fluoxetine; Humans; Male; Mice; Mice, Inbred C57BL; Neuro | 2023 |
Adult hippocampal neurogenesis and social behavioural deficits in the R451C Neuroligin3 mouse model of autism are reverted by the antidepressant fluoxetine.
Topics: Animals; Antidepressive Agents; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; | 2023 |
Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics.
Topics: Autism Spectrum Disorder; Autistic Disorder; Fluoxetine; Humans; Induced Pluripotent Stem Cells; Res | 2023 |
Fluoxetine and Repetitive Behaviors in Children and Adolescents With Autism Spectrum Disorder.
Topics: Adolescent; Autism Spectrum Disorder; Autistic Disorder; Child; Cognition; Compulsive Behavior; Fluo | 2019 |
Obsessive-Compulsive Behaviors in Autism.
Topics: Adolescent; Autism Spectrum Disorder; Autistic Disorder; Child; Compulsive Behavior; Fluoxetine; Hum | 2020 |
Maternal fluoxetine reduces hippocampal inflammation and neurogenesis in adult offspring with sex-specific effects of periadolescent oxytocin.
Topics: Adult Children; Animals; Autism Spectrum Disorder; Doublecortin Protein; Female; Fluoxetine; Hippoca | 2021 |
Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Brain; Carbamazepine; Environment; Female; Flu | 2017 |
Excessive Masturbation Successfully Treated with Fluoxetine in an Adolescent with Autism Spectrum Disorder and Coexisting Depression.
Topics: Adolescent; Autism Spectrum Disorder; Comorbidity; Depression; Female; Fluoxetine; Humans; Male; Mas | 2018 |
Exposure to Acute and Chronic Fluoxetine has Differential Effects on Sociability and Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus of Juvenile Male BALB/c Mice.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Autism Spectrum Disorder; Dorsal Raphe Nucleus; Fluoxetin | 2018 |
Selective mutism in a child with autism spectrum disorder: A case report and an approach to the management in such difficult to treat scenario in children.
Topics: Autism Spectrum Disorder; Behavior Therapy; Child; Combined Modality Therapy; Fluoxetine; Humans; Ma | 2018 |
Fluoxetine Affects Differentiation of Midbrain Dopaminergic Neurons In Vitro.
Topics: Animals; Autism Spectrum Disorder; Cell Differentiation; Cells, Cultured; Dopamine; Dopaminergic Neu | 2018 |
CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Brain; CRISPR-Cas Systems; Disease Models, Anim | 2019 |
Perinatal fluoxetine exposure results in social deficits and reduced monoamine oxidase gene expression in mice.
Topics: Animals; Antidepressive Agents; Autism Spectrum Disorder; Behavior, Animal; Brain; Exploratory Behav | 2020 |
Staying Up at Night: Overlapping Bipolar and Obsessive-Compulsive Disorder Symptoms in an Adolescent with Autism Spectrum Disorder.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Autism Spectrum Disorder | 2016 |
Diagnosis and treatment of obsessive compulsive behavior in a boy with Duchenne muscular dystrophy and autism spectrum disorder: A case report.
Topics: Autism Spectrum Disorder; Child; Comorbidity; Fluoxetine; Humans; Male; Muscular Dystrophy, Duchenne | 2016 |