Page last updated: 2024-10-27

fluoxetine and Aura

fluoxetine has been researched along with Aura in 37 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"Nineteen mentally retarded inpatients with epilepsy and a history of current or recent aggressive behavior were treated with 20 mg of fluoxetine daily."9.08Effects of fluoxetine on aggressive behavior of adult inpatients with mental retardation and epilepsy. ( Ciani, N; Nuccetelli, F; Pasini, A; Troisi, A; Vicario, E, 1995)
"Serotonin and fluoxetine, but not sumatriptan, alleviated PTZ-induced seizures by prolonging onset times of myoclonic-jerk and generalized tonic-clonic seizures."8.12Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats. ( Kilinc, E; Kılınc, YB; Torun, IE, 2022)
" The main objective of this work was to investigate the effect of the selective 5-HT selective reuptake inhibitor (SSRI) fluoxetine administered subacutely (10mg/kg/day×7 days) on the eventual metabolic impairment induced by the lithium-pilocarpine model of epilepsy in rats."7.81Subacute administration of fluoxetine prevents short-term brain hypometabolism and reduces brain damage markers induced by the lithium-pilocarpine model of epilepsy in rats. ( Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA, 2015)
"Status epilepticus was induced in the rats by administration of pilocarpine 350 mg/kg i."7.77Piperine protects epilepsy associated depression: a study on role of monoamines. ( Nayak, S; Pal, A; Sahu, PK; Swain, T, 2011)
"Fluoxetine (20 mg/kg) and TFMPP (5 mg/kg) were administered to rats with pilocarpine-induced epilepsy."7.71Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy. ( Dudek, FE; Hernandez, EJ; Williams, PA, 2002)
"This study was designed to demonstrate a role of serotonin in the anticonvulsant effect of fluoxetine, a serotonin reuptake inhibitor, in genetically epilepsy-prone rats."7.69Role of serotonin in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats. ( Cheong, JH; Dailey, JW; Jobe, PC; Ko, KH; Yan, QS, 1994)
"To test the hypothesis that fluoxetine may be a useful adjunct to antiepileptic therapy, we treated with fluoxetine (20-40 mg/day) nine patients suffering from medically intractable epilepsy with daily seizures."7.69Lack of potentiation of anticonvulsant effect by fluoxetine in drug-resistant epilepsy. ( Baldinetti, F; Diomedi, M; Gigli, GL; Girolami, E; Marciani, MG; Pasini, A; Troisi, A, 1994)
"Fluoxetine, an antidepressant and inhibitor of serotonin reuptake, was evaluated as an anticonvulsant in genetically epilepsy-prone rats (GEPRs) because seizure predisposition in GEPRs is partially dependent on deficits in brain serotonin."7.68Effects of fluoxetine on convulsions and on brain serotonin as detected by microdialysis in genetically epilepsy-prone rats. ( Burger, RL; Dailey, JW; Jobe, PC; Mishra, PK; Yan, QS, 1992)
"Furthermore, children with highly refractory epilepsy are at particular risk of sudden unexpected death."5.62Fluoxetine as adjunctive therapy in pediatric patients with refractory epilepsy: A retrospective analysis. ( Desnous, B; Milh, M; Neveu, J; Villeneuve, N, 2021)
"In this sample of children and adolescents with epilepsy and depressive disorders, we observed that SSRIs are a good therapeutic option, considering their efficacy in remission of depressive symptoms, their few adverse effects, and their maintenance of satisfactory seizure control."5.34Sertraline and fluoxetine: safe treatments for children and adolescents with epilepsy and depression. ( Kuczynski, E; Thomé-Souza, MS; Valente, KD, 2007)
"Nineteen mentally retarded inpatients with epilepsy and a history of current or recent aggressive behavior were treated with 20 mg of fluoxetine daily."5.08Effects of fluoxetine on aggressive behavior of adult inpatients with mental retardation and epilepsy. ( Ciani, N; Nuccetelli, F; Pasini, A; Troisi, A; Vicario, E, 1995)
"Pregabalin (PGB) is used in drug-resistant epilepsy."4.31The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats. ( Aydın, Ş; Çivgin, ME; Dinçer Öner, S; Kılıç Tatlıcı, C; Kılıç, FS; Yazıcı, ZG; Yıldırım, C, 2023)
"Serotonin and fluoxetine, but not sumatriptan, alleviated PTZ-induced seizures by prolonging onset times of myoclonic-jerk and generalized tonic-clonic seizures."4.12Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats. ( Kilinc, E; Kılınc, YB; Torun, IE, 2022)
" The main objective of this work was to investigate the effect of the selective 5-HT selective reuptake inhibitor (SSRI) fluoxetine administered subacutely (10mg/kg/day×7 days) on the eventual metabolic impairment induced by the lithium-pilocarpine model of epilepsy in rats."3.81Subacute administration of fluoxetine prevents short-term brain hypometabolism and reduces brain damage markers induced by the lithium-pilocarpine model of epilepsy in rats. ( Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA, 2015)
"Status epilepticus was induced in the rats by administration of pilocarpine 350 mg/kg i."3.77Piperine protects epilepsy associated depression: a study on role of monoamines. ( Nayak, S; Pal, A; Sahu, PK; Swain, T, 2011)
" In this study the anticonvulsant actions of norfluoxetine and fluoxetine were studied and compared to those of phenytoin and clonazepam in pentylenetetrazol-induced mouse epilepsy models."3.73Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies. ( Harasztosi, C; Kecskeméti, V; Nánási, PP; Pál, B; Riba, P; Rusznák, Z; Szûcs, G; Wagner, R, 2005)
"Fluoxetine (20 mg/kg) and TFMPP (5 mg/kg) were administered to rats with pilocarpine-induced epilepsy."3.71Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy. ( Dudek, FE; Hernandez, EJ; Williams, PA, 2002)
"This study was designed to demonstrate a role of serotonin in the anticonvulsant effect of fluoxetine, a serotonin reuptake inhibitor, in genetically epilepsy-prone rats."3.69Role of serotonin in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats. ( Cheong, JH; Dailey, JW; Jobe, PC; Ko, KH; Yan, QS, 1994)
"To test the hypothesis that fluoxetine may be a useful adjunct to antiepileptic therapy, we treated with fluoxetine (20-40 mg/day) nine patients suffering from medically intractable epilepsy with daily seizures."3.69Lack of potentiation of anticonvulsant effect by fluoxetine in drug-resistant epilepsy. ( Baldinetti, F; Diomedi, M; Gigli, GL; Girolami, E; Marciani, MG; Pasini, A; Troisi, A, 1994)
"Fluoxetine, an antidepressant and inhibitor of serotonin reuptake, was evaluated as an anticonvulsant in genetically epilepsy-prone rats (GEPRs) because seizure predisposition in GEPRs is partially dependent on deficits in brain serotonin."3.68Effects of fluoxetine on convulsions and on brain serotonin as detected by microdialysis in genetically epilepsy-prone rats. ( Burger, RL; Dailey, JW; Jobe, PC; Mishra, PK; Yan, QS, 1992)
"Furthermore, children with highly refractory epilepsy are at particular risk of sudden unexpected death."1.62Fluoxetine as adjunctive therapy in pediatric patients with refractory epilepsy: A retrospective analysis. ( Desnous, B; Milh, M; Neveu, J; Villeneuve, N, 2021)
"Depression is the most common psychiatric comorbidity of epilepsy."1.62Chronically altered NMDAR signaling in epilepsy mediates comorbid depression. ( Dehpour, AR; Hemmati, S; Mohammadi, S; Sadeghi, MA; Vafaei, A; Yousefi-Manesh, H; Zare, M, 2021)
"In this sample of children and adolescents with epilepsy and depressive disorders, we observed that SSRIs are a good therapeutic option, considering their efficacy in remission of depressive symptoms, their few adverse effects, and their maintenance of satisfactory seizure control."1.34Sertraline and fluoxetine: safe treatments for children and adolescents with epilepsy and depression. ( Kuczynski, E; Thomé-Souza, MS; Valente, KD, 2007)
"When fluoxetine (3 microM) was applied first neither nifedipine nor omega-conotoxin attenuated the remaining component of the HVA current."1.31Inhibition of voltage-gated calcium channels by fluoxetine in rat hippocampal pyramidal cells. ( Deák, F; Lasztóczi, B; Pacher, P; Petheö, GL; Spät, A, 2000)
"With conservative dosing and close monitoring, combinations of SRIs with bupropion in this uncontrolled clinical series appeared to be safe and often more effective than monotherapy."1.30Combining serotonin reuptake inhibitors and bupropion in partial responders to antidepressant monotherapy. ( Baldessarini, RJ; Bodkin, JA; Gardner, DM; Lasser, RA; Wines, JD, 1997)
"Pretreatment with prazosin (1 microgram/side) significantly diminished the anticonvulsant effectiveness of methoxamine and nisoxetine while prazosin, by itself, had no effects on the seizure intensity."1.30Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study. ( Dailey, JW; Jobe, PC; Steenbergen, JL; Yan, QS, 1998)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (43.24)18.2507
2000's7 (18.92)29.6817
2010's10 (27.03)24.3611
2020's4 (10.81)2.80

Authors

AuthorsStudies
Vivier, D1
Bennis, K1
Lesage, F1
Ducki, S1
Neveu, J1
Villeneuve, N1
Milh, M1
Desnous, B1
Torun, IE1
Kılınc, YB1
Kilinc, E1
Aydın, Ş1
Kılıç Tatlıcı, C1
Çivgin, ME1
Yazıcı, ZG1
Yıldırım, C1
Dinçer Öner, S1
Kılıç, FS1
Sadeghi, MA1
Hemmati, S1
Mohammadi, S1
Yousefi-Manesh, H1
Vafaei, A1
Zare, M1
Dehpour, AR1
Lovick, T1
Cardamone, L1
Salzberg, MR1
Koe, AS1
Ozturk, E1
O'Brien, TJ1
Jones, NC1
Puzerey, PA1
Decker, MJ1
Galán, RF1
Shiha, AA1
de Cristóbal, J1
Delgado, M1
Fernández de la Rosa, R1
Bascuñana, P1
Pozo, MA1
García-García, L1
Zeng, C1
Long, X1
Cotten, JF1
Forman, SA1
Solt, K1
Faingold, CL1
Feng, HJ1
Lance, S1
Ternouth, I1
Choi, HC1
Kim, YI1
Song, HK1
Kim, JE1
Kim, DS1
Kang, TC1
Pal, A1
Nayak, S1
Sahu, PK1
Swain, T1
Pineda, EA1
Hensler, JG1
Sankar, R1
Shin, D1
Burke, TF1
Mazarati, AM1
Hernandez, EJ1
Williams, PA1
Dudek, FE1
Kecskeméti, V1
Rusznák, Z1
Riba, P1
Pál, B1
Wagner, R1
Harasztosi, C1
Nánási, PP1
Szûcs, G1
Albano, C3
Cupello, A1
Mainardi, P3
Scarrone, S1
Favale, E2
Thomé-Souza, MS1
Kuczynski, E1
Valente, KD1
Merrill, MA1
Clough, RW1
Dailey, JW5
Jobe, PC5
Browning, RA1
Rubino, V2
Lunardi, G2
Yan, QS4
Cheong, JH1
Ko, KH1
Troisi, A3
Vicario, E1
Nuccetelli, F1
Ciani, N1
Pasini, A2
Gigli, GL1
Diomedi, M1
Baldinetti, F1
Marciani, MG1
Girolami, E1
Darley, J1
Friedman, EH1
Fracassi, M1
Pioli, F1
Cultrera, S1
Bodkin, JA1
Lasser, RA1
Wines, JD1
Gardner, DM1
Baldessarini, RJ1
Steenbergen, JL1
Lu, KT1
Gean, PW1
Deák, F1
Lasztóczi, B1
Pacher, P1
Petheö, GL1
Spät, A1
Romerio, SC1
Radanowicz, V1
Schlienger, RG1
Droulers, A1
Bodak, N1
Oudjhani, M1
Lefevre des Noettes, V1
Bodak, A1
Jalil, P1
Mishra, PK1
Burger, RL1
Thompson, PM1
Zebrowski, G1
Neuman, RS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) a Multicentre Open-label Randomized Controlled Trial Protocol[NCT05814640]Phase 1/Phase 2520 participants (Anticipated)Interventional2023-02-20Recruiting
Double-Blind, Placebo-Controlled, Randomized Trial of Adjunctive Lisdexamfetamine Dimesylate in Residual Symptoms of Major Depressive Disorder Partially Responsive to Selective Serotonin or Norepinephrine Reuptake Inhibitor Monotherapy[NCT01148979]Phase 435 participants (Actual)Interventional2010-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in the Dysphoric Apathy/Retardation Sub-factor (MDAR) of Montgomery-Asberg Depression Rating Scale (MADRS) at 4 Weeks.

The Montgomery-Asberg Depression Rating Scale Dysphoric Apathy Retardation subfactor (MDAR) is a 5-item subscale of the clinician-administered 10-item Montgomery-Asberg Depression Rating Scale (MADRS). MDAR score can range from 0-30 with a higher score representing a greater severity of depressive symptoms. (NCT01148979)
Timeframe: Baseline to 4 weeks of treatment

,
Interventionscores on a scale (Mean)
Baseline Mean MDAR scoreWeek 4 Mean MDAR scoreChange from BL in mean MDAR score
Lisdexamfetamine Dimesylate (Vyvanse)13.466.36-7.08
Placebo Adjunct12.579.08-3.49

Reviews

1 review available for fluoxetine and Aura

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc

2016

Trials

1 trial available for fluoxetine and Aura

ArticleYear
Effects of fluoxetine on aggressive behavior of adult inpatients with mental retardation and epilepsy.
    Pharmacopsychiatry, 1995, Volume: 28, Issue:3

    Topics: Adult; Aggression; Epilepsy; Female; Fluoxetine; Humans; Individuality; Intellectual Disability; Mal

1995

Other Studies

35 other studies available for fluoxetine and Aura

ArticleYear
Fluoxetine as adjunctive therapy in pediatric patients with refractory epilepsy: A retrospective analysis.
    Epilepsy research, 2021, Volume: 177

    Topics: Adult; Anticonvulsants; Child; Drug Resistant Epilepsy; Epilepsy; Fluoxetine; Humans; Retrospective

2021
Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats.
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:1

    Topics: Animals; Anticonvulsants; Epilepsy; Fluoxetine; Humans; Interleukin-6; Male; Neuroinflammatory Disea

2022
The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2023, Volume: 35, Issue:4

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Epilepsy; Fluoxetine; Humans; Ke

2023
Chronically altered NMDAR signaling in epilepsy mediates comorbid depression.
    Acta neuropathologica communications, 2021, 03-24, Volume: 9, Issue:1

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Depression; Epilepsy; Fluoxetine; Indazoles; Male;

2021
SSRIs and the female brain--potential for utilizing steroid-stimulating properties to treat menstrual cycle-linked dysphorias.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:12

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Epilepsy; Female; Fluoxetine; GABAergic Neurons; H

2013
Chronic antidepressant treatment accelerates kindling epileptogenesis in rats.
    Neurobiology of disease, 2014, Volume: 63

    Topics: Amygdala; Analysis of Variance; Animals; Antidepressive Agents; Drug Delivery Systems; Electric Stim

2014
Elevated serotonergic signaling amplifies synaptic noise and facilitates the emergence of epileptiform network oscillations.
    Journal of neurophysiology, 2014, Nov-15, Volume: 112, Issue:10

    Topics: Animals; Computer Simulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Excitatory Po

2014
Subacute administration of fluoxetine prevents short-term brain hypometabolism and reduces brain damage markers induced by the lithium-pilocarpine model of epilepsy in rats.
    Brain research bulletin, 2015, Volume: 111

    Topics: Animals; Apoptosis; Astrocytes; Brain; Caspase 3; Disease Models, Animal; Epilepsy; Fluoxetine; Gluc

2015
Fluoxetine prevents respiratory arrest without enhancing ventilation in DBA/1 mice.
    Epilepsy & behavior : E&B, 2015, Volume: 45

    Topics: Animals; Death, Sudden; Disease Models, Animal; Epilepsy; Fluoxetine; Mice; Mice, Inbred DBA; Pulmon

2015
Fluoxetine-induced phenytoin toxicity: a clinical reminder about the perils of polypharmacy.
    The New Zealand medical journal, 2015, Sep-25, Volume: 128, Issue:1422

    Topics: Antidepressive Agents, Second-Generation; Drug Interactions; Epilepsy; Female; Fluoxetine; Humans; M

2015
Effects of selective serotonin reuptake inhibitors on GABAergic inhibition in the hippocampus of normal and pilocarpine induced epileptic rats.
    Brain research, 2010, Oct-21, Volume: 1357

    Topics: Analysis of Variance; Animals; Citalopram; Electroencephalography; Epilepsy; Fluoxetine; gamma-Amino

2010
Piperine protects epilepsy associated depression: a study on role of monoamines.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:11

    Topics: Alkaloids; Anhedonia; Animals; Anticonvulsants; Behavior, Animal; Benzodioxoles; Biogenic Monoamines

2011
Interleukin-1β causes fluoxetine resistance in an animal model of epilepsy-associated depression.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012, Volume: 9, Issue:2

    Topics: Animals; Antidepressive Agents, Second-Generation; Depression; Disease Models, Animal; Drug Resistan

2012
Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy.
    Epilepsia, 2002, Volume: 43, Issue:11

    Topics: Animals; Convulsants; Epilepsy; Fluoxetine; Male; Pilocarpine; Piperazines; Rats; Rats, Sprague-Dawl

2002
Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies.
    Brain research bulletin, 2005, Sep-30, Volume: 67, Issue:1-2

    Topics: Animals; Anticonvulsants; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signa

2005
Successful treatment of epilepsy with serotonin reuptake inhibitors: proposed mechanism.
    Neurochemical research, 2006, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acids; Citalopram; Clinical Trials as Topic; Epilepsy; Female; Fluoxe

2006
Sertraline and fluoxetine: safe treatments for children and adolescents with epilepsy and depression.
    Epilepsy & behavior : E&B, 2007, Volume: 10, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Depression; Epilepsy; Female; Fluoxetine; Humans; Male; Neurolo

2007
Localization of the serotonergic terminal fields modulating seizures in the genetically epilepsy-prone rat.
    Epilepsy research, 2007, Volume: 76, Issue:2-3

    Topics: Animals; Brain; Dihydroxytryptamines; Epilepsy; Epilepsy, Reflex; Female; Fluoxetine; Infusions, Par

2007
Anticonvulsant effect of fluoxetine in humans.
    Neurology, 1995, Volume: 45, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Fluoxetine; Humans; Male; Middle Aged

1995
Role of serotonin in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Epilepsy; Female; Fenclonine; Fluoxetine; Hydroxyindo

1994
Lack of potentiation of anticonvulsant effect by fluoxetine in drug-resistant epilepsy.
    Seizure, 1994, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Depressive Disorder; Dose-Response Relationship, Drug; Drug Ther

1994
Interaction between phenytoin and fluoxetine.
    Seizure, 1994, Volume: 3, Issue:2

    Topics: Adult; Depressive Disorder; Dose-Response Relationship, Drug; Epilepsy; Fluoxetine; Humans; Male; Ph

1994
Evidence that a serotonergic mechanism is involved in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats.
    European journal of pharmacology, 1994, Jan-24, Volume: 252, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Epilepsy; Fem

1994
Fluoxetine and aggressive behaviour.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:3

    Topics: Adult; Aggression; Epilepsy; Fluoxetine; Humans; Intellectual Disability; Selective Serotonin Reupta

1996
Tryptophan and epilepsy.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Anticonvulsants; Blood-Brain Barrier; Brain; Epilepsy; Fluoxetine; Humans; Selective Serotonin Reupt

1996
Fluoxetine and aggression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:5

    Topics: Aggression; Animals; Behavior, Animal; Epilepsy; Fluoxetine; Humans; Intellectual Disability; Rats

1997
Combining serotonin reuptake inhibitors and bupropion in partial responders to antidepressant monotherapy.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:4

    Topics: 1-Naphthylamine; Adult; Aged; Ambulatory Care; Anxiety Disorders; Bupropion; Depressive Disorder; Dr

1997
Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study.
    Brain research, 1998, Jan-12, Volume: 780, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Anti

1998
Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation.
    Neuroscience, 1998, Volume: 86, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Barium; Epilepsy; Excitatory Postsynaptic Potential

1998
Inhibition of voltage-gated calcium channels by fluoxetine in rat hippocampal pyramidal cells.
    Neuropharmacology, 2000, Apr-03, Volume: 39, Issue:6

    Topics: Action Potentials; Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Calcium Chann

2000
[SIADH with epileptic seizures and coma in fluoxetine therapy].
    Praxis, 2000, Mar-02, Volume: 89, Issue:10

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Coma; Depressive Disorder; Electr

2000
Decrease of valproic acid concentration in the blood when coprescribed with fluoxetine.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:2

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Antidepressive Agents, Second-Generation; Depressive Disor

1997
Toxic reaction following the combined administration of fluoxetine and phenytoin: two case reports.
    Journal of neurology, neurosurgery, and psychiatry, 1992, Volume: 55, Issue:5

    Topics: Aged; Aged, 80 and over; Depressive Disorder; Drug Therapy, Combination; Epilepsy; Female; Fluoxetin

1992
Effects of fluoxetine on convulsions and on brain serotonin as detected by microdialysis in genetically epilepsy-prone rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Animals; Brain; Dialysis; Epilepsy; Female; Fluoxetine; Male; Rats; Seizures; Serotonin; Thalamus

1992
Alteration of neocortical activity in response to noxious stimulation: participation of the dorsal raphe.
    Neuropharmacology, 1991, Volume: 30, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Baclofen; Cerebral Cortex; Cortical Synchronization

1991