Page last updated: 2024-10-27

fluoxetine and Atrophy

fluoxetine has been researched along with Atrophy in 8 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"To further explore the underlying antidepressant mechanism of ginseng total saponins (GTS), this study observed the effects on hippocampal astrocyte structural plasticity and hippocampal volume in the corticosterone-induced mouse depression model."7.85Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy. ( Chen, L; Dai, JG; Huang, YF; Lin, ZX; Wang, X; Zhao, YN, 2017)
"To study the effect of fluoxetine on dendrite atrophy of hippocampal neurons in rat depression model."7.71Fluoxetine inhibits dendrite atrophy of hippocampal neurons by decreasing nitric oxide synthase expression in rat depression model. ( Luo, L; Tan, RX, 2001)
"To further explore the underlying antidepressant mechanism of ginseng total saponins (GTS), this study observed the effects on hippocampal astrocyte structural plasticity and hippocampal volume in the corticosterone-induced mouse depression model."3.85Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy. ( Chen, L; Dai, JG; Huang, YF; Lin, ZX; Wang, X; Zhao, YN, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, L2
Wang, X1
Lin, ZX1
Dai, JG1
Huang, YF1
Zhao, YN1
Zhao, Y1
Lin, Z1
Ouyang, L1
Gu, L1
Chen, F1
Zhang, Q1
Morais, M1
Santos, PA1
Mateus-Pinheiro, A1
PatrĂ­cio, P1
Pinto, L1
Sousa, N1
Pedroso, P1
Almeida, S1
Filipe, A1
Bessa, JM1
Jin, P1
Yu, HL1
Zhang, F1
Quan, ZS1
Fontenelle, LF1
Leite, MA1
Hoexter, MQ1
Dougherty, DD1
Shavitt, RG1
D'Alcante, CC1
Duran, FL1
Lopes, AC1
Diniz, JB1
Batistuzzo, MC1
Evans, KC1
Bressan, RA1
Busatto, GF1
Miguel, EC1
Mendhekar, DN1
Luo, L1
Tan, RX1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Group Cognitive Behavioral Therapy Versus Fluoxetine for Obsessive-Compulsive Disorder: a Randomized Open Trial for Any Patient.[NCT00680602]Phase 4158 participants (Actual)Interventional2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fluoxetine and Atrophy

ArticleYear
Differential prefrontal gray matter correlates of treatment response to fluoxetine or cognitive-behavioral therapy in obsessive-compulsive disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:7

    Topics: Adult; Atrophy; Cognitive Behavioral Therapy; Female; Fluoxetine; Humans; Male; Nerve Fibers, Unmyel

2013

Other Studies

7 other studies available for fluoxetine and Atrophy

ArticleYear
Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy.
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:9

    Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depression; Disease Models, Ani

2017
Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 04-20, Volume: 83

    Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depressive Disorder; Diazepam;

2018
The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition.
    Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:12

    Topics: Animals; Atrophy; Carbazoles; Dendrites; Dose-Response Relationship, Drug; Fluoxetine; Hippocampus;

2014
Antidepressant-like effects of oleoylethanolamide in a mouse model of chronic unpredictable mild stress.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 133

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antioxidants; Atrophy; Brain-Derived Ne

2015
Treatment-resistant self-mutilation, tics, and obsessive-compulsive disorder in neuroacanthocytosis: a mouth guard as a therapeutic approach.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:7

    Topics: Adult; Antipsychotic Agents; Atrophy; Caudate Nucleus; Clonazepam; Clozapine; Dibenzothiazepines; El

2008
Fluoxetine-induced breast atrophy.
    The Australian and New Zealand journal of psychiatry, 2004, Volume: 38, Issue:5

    Topics: Adult; Atrophy; Breast; Dysthymic Disorder; Female; Fluoxetine; Humans; Selective Serotonin Reuptake

2004
Fluoxetine inhibits dendrite atrophy of hippocampal neurons by decreasing nitric oxide synthase expression in rat depression model.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:10

    Topics: Animals; Antidepressive Agents, Second-Generation; Atrophy; Dendrites; Depression; Fluoxetine; Hippo

2001