Page last updated: 2024-10-27

fluoxetine and Asthma

fluoxetine has been researched along with Asthma in 4 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Depression is very common in asthmatic patients and may increases risk for morbidity and mortality."5.48Fluoxetine protects against OVA induced bronchial asthma and depression in rats. ( Abo-Youssef, AM; Ismaiel, IE; Salama, AAA; Sherkawy, MM, 2018)
"Depression is very common in asthmatic patients and may increases risk for morbidity and mortality."1.48Fluoxetine protects against OVA induced bronchial asthma and depression in rats. ( Abo-Youssef, AM; Ismaiel, IE; Salama, AAA; Sherkawy, MM, 2018)
"In the septic shock model, all three drugs given preventively markedly decreased circulating levels of TNF-alpha and mortality (50% mortality in fluoxetine treated group, 30% in desipramine and prednisolone treated groups versus 90% in controls)."1.34Anti-inflammatory properties of desipramine and fluoxetine. ( Bichon, F; Detoc, M; Henriquet, C; Jaffuel, D; Mathieu, M; Michel, A; Portet, K; Roumestan, C, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casan, P1
Fernández Tena, A1
Martínez, C1
Sherkawy, MM1
Abo-Youssef, AM1
Salama, AAA1
Ismaiel, IE1
Roumestan, C1
Michel, A1
Bichon, F1
Portet, K1
Detoc, M1
Henriquet, C1
Jaffuel, D1
Mathieu, M1
Zaitsev, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)[NCT04570449]Early Phase 10 participants (Actual)Interventional2020-11-30Withdrawn (stopped due to Study timeline is not feasible)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for fluoxetine and Asthma

ArticleYear
More Platon And Less Prozac: The Arrival Of ASTHMA-ZUMAB.
    Archivos de bronconeumologia, 2018, Volume: 54, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Antibodies, Monoclonal; Asthma; Attitude of Health P

2018
Fluoxetine protects against OVA induced bronchial asthma and depression in rats.
    European journal of pharmacology, 2018, Oct-15, Volume: 837

    Topics: Animals; Asthma; Brain-Derived Neurotrophic Factor; Depression; Dexamethasone; Fluoxetine; Immunoglo

2018
Anti-inflammatory properties of desipramine and fluoxetine.
    Respiratory research, 2007, May-03, Volume: 8

    Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Asthma; Cells, Cultured; Cytokines; Desipr

2007
[Dyspnoea of a young male patient].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Asthma; Diagnosis, Differential; Dyspnea; Fluoxetin

1996