Page last updated: 2024-10-27

fluoxetine and As If Personality

fluoxetine has been researched along with As If Personality in 37 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study is to identify associations between regional serotonin transporter (5-HTT) availability and trait and state aggression, as well as response to the anti-aggressive effects of fluoxetine."8.31Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine. ( Abi-Dargham, A; Carson, RE; Hazlett, EA; Huang, Y; Koenigsberg, HW; McClure, MM; Nabulsi, N; New, AS; Perez-Rodriguez, MM; Rosell, DR; Siever, LS; Slifstein, M; Thompson, J; Xu, X, 2023)
"Combined therapy with adapted IPT was superior to fluoxetine alone in BPD patients, concerning a few core symptoms of the disorder, anxiety, and quality of life."5.14Adaptation of interpersonal psychotherapy to borderline personality disorder: a comparison of combined therapy and single pharmacotherapy. ( Bellino, S; Bogetto, F; Rinaldi, C, 2010)
"Fluoxetine, but not placebo, treatment resulted in a sustained reduction in scores on the Irritability and Aggression subscales of the Overt Aggression Scale-Modified for Outpatients that was first apparent during months 2 and 3 of treatment, respectively."5.08Fluoxetine and impulsive aggressive behavior in personality-disordered subjects. ( Coccaro, EF; Kavoussi, RJ, 1997)
"The aim of this study is to identify associations between regional serotonin transporter (5-HTT) availability and trait and state aggression, as well as response to the anti-aggressive effects of fluoxetine."4.31Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine. ( Abi-Dargham, A; Carson, RE; Hazlett, EA; Huang, Y; Koenigsberg, HW; McClure, MM; Nabulsi, N; New, AS; Perez-Rodriguez, MM; Rosell, DR; Siever, LS; Slifstein, M; Thompson, J; Xu, X, 2023)
"Two hundred and fifteen outpatients with major depressive disorder as assessed with the Structured Clinical Interview for DSM-III-R (SCID-P) were treated openly with fluoxetine 20 mg/day for 8 weeks."3.70Residual symptoms in depressed patients who respond acutely to fluoxetine. ( Alpert, JE; Fava, M; Keefe, BR; Leslie, VC; Nierenberg, AA; Pava, JA; Rosenbaum, JF; Worthington, JJ, 1999)
"Although selective serotonin reuptake inhibitors (SSRI) are generally effective in reducing impulsive aggression in individuals with intermittent explosive disorder, a large proportion of intermittent explosive disorder patients fail to achieve full remission despite adequate dosage and duration of treatment."2.76Personality predictors of antiaggressive response to fluoxetine: inverse association with neuroticism and harm avoidance. ( Coccaro, EF; Lee, R; Phan, KL, 2011)
"Personality disorders are neither particularly stable nor treatment resistant."2.75Personality disorders improve in patients treated for major depression. ( Frampton, CM; Joyce, PR; Mulder, RT, 2010)
"Treatment with fluoxetine is less likely to lead to remission of MDD in patients with stable PDs."2.72Problem-solving ability and comorbid personality disorders in depressed outpatients. ( Farabaugh, A; Fava, M; Harley, R; Papakostas, GI; Petersen, T; Scalia, M, 2006)
" Divalproex sodium was increased as tolerated using a flexible dosing schedule."2.69Divalproex sodium for impulsive aggressive behavior in patients with personality disorder. ( Coccaro, EF; Kavoussi, RJ, 1998)
"Patients with unipolar depression and anger attacks frequently experience significant anxiety and somatic symptoms, and are relatively more likely to meet criteria for avoidant, dependent, borderline, narcissistic, and antisocial personality disorders than depressed patients without these attacks."2.40Depression with anger attacks. ( Fava, M, 1998)
"Persistence of hypochondriasis was individually predicted by longer duration of prior hypochondriasis (P = 0."1.37Long-term follow-up of hypochondriasis after selective serotonin reuptake inhibitor treatment. ( Fallon, BA; Pavlicova, M; Schweitzer, PJ; Zafar, U, 2011)
"Patients meeting DSM-IV criteria for major depressive disorder (MDD) entered randomized, controlled medication trials."1.30Defense mechanisms and personality in depression. ( Blanco, C; Mullen, LS; Roose, SP; Vaughan, R; Vaughan, SC, 1999)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (43.24)18.2507
2000's14 (37.84)29.6817
2010's6 (16.22)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Rosell, DR1
Slifstein, M1
Thompson, J1
Xu, X1
Perez-Rodriguez, MM1
McClure, MM1
Hazlett, EA1
New, AS1
Nabulsi, N1
Huang, Y1
Carson, RE1
Siever, LS1
Abi-Dargham, A1
Koenigsberg, HW1
Candrian, M2
Schwartz, F2
Farabaugh, A4
Perlis, RH1
Ehlert, U1
Fava, M11
Mulder, RT6
Frampton, CM2
Luty, SE5
Joyce, PR6
Dording, CM1
Sinicropi-Yao, L1
Papakostas, G1
Matthews, JD1
Nierenberg, AA4
Mischoulon, D2
Silva, H1
Iturra, P1
Solari, A1
Villarroel, J1
Jerez, S1
Jiménez, M1
Galleguillos, F1
Bustamante, ML1
Bellino, S2
Rinaldi, C1
Bogetto, F2
Ginsburg, GS1
Silva, SG1
Jacobs, RH1
Tonev, S1
Hoyle, RH1
Kingery, JN1
Reinecke, MA1
Curry, JF1
March, JS1
De Bolle, M1
De Fruyt, F1
Quilty, LC1
Rolland, JP1
Decuyper, M1
Bagby, RM1
Schweitzer, PJ1
Zafar, U1
Pavlicova, M1
Fallon, BA1
Phan, KL1
Lee, R1
Coccaro, EF5
Agosti, V1
McGrath, PJ1
Farabaugh, AH1
Sickinger, AH1
Wright, E1
Alpert, JE3
Sonawalla, S1
Worthington, JJ2
Rogers, GR1
Miller, AL1
Kennedy, MA1
McKenzie, JM2
Carter, JD1
Sullivan, PF2
Cloninger, CR1
McIntosh, VV1
Carter, FA1
Bulik, CM1
Harley, R1
Petersen, T1
Scalia, M1
Papakostas, GI1
Pender, M1
Alpert, J1
Huppert, JD1
Strunk, DR1
Ledley, DR1
Davidson, JR1
Foa, EB1
Pizzagalli, DA1
Baer, L1
Tuinier, S1
Verhoeven, WM1
Barzega, G1
Maina, G1
Ravizza, L1
Bouffides, E2
Pava, JA3
McCarthy, MK2
Steingard, RJ2
Rosenbaum, JF4
Shea, MT1
Akiskal, H1
Tedlow, JR1
Uebelacker, LA1
Black, KJ1
Sheline, YI1
Kavoussi, RJ3
Hauger, RL1
Benjamin, LS1
Keefe, BR1
Leslie, VC1
Mullen, LS1
Blanco, C1
Vaughan, SC1
Vaughan, R1
Roose, SP1
Astill, JL1
Herbert, JL1
Schut, AG1

Reviews

4 reviews available for fluoxetine and As If Personality

ArticleYear
Dimensional classification and behavioral pharmacology of personality disorders; a review and hypothesis.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:2

    Topics: Adaptation, Psychological; Antipsychotic Agents; Borderline Personality Disorder; Clinical Trials as

1995
Personality disorders and depression: an overview of issues and findings.
    Rhode Island medicine, 1993, Volume: 76, Issue:8

    Topics: Comorbidity; Depressive Disorder; Female; Fluoxetine; Humans; Male; Monoamine Oxidase Inhibitors; Pe

1993
Special feature: personality disorders: models for treatment and strategies for treatment development.
    Journal of personality disorders, 1997,Winter, Volume: 11, Issue:4

    Topics: Adult; Behavior Therapy; Clinical Protocols; Clinical Trials as Topic; Cognitive Behavioral Therapy;

1997
Depression with anger attacks.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 18

    Topics: Aggression; Ambulatory Care; Anger; Antidepressive Agents; Arousal; Comorbidity; Depressive Disorder

1998

Trials

21 trials available for fluoxetine and As If Personality

ArticleYear
Personality disorders and perceived stress in major depressive disorder.
    Psychiatry research, 2008, Aug-15, Volume: 160, Issue:2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Comorbidity; Depressive Disorder, Major; Diagnostic and St

2008
Eighteen months of drug treatment for depression: predicting relapse and recovery.
    Journal of affective disorders, 2009, Volume: 114, Issue:1-3

    Topics: Adolescent; Adult; Analysis of Variance; Antidepressive Agents; Depressive Disorder; Dose-Response R

2009
The response of psychotic-like symptoms to fluoxetine monotherapy in non-psychotic major depressive disorder.
    Nordic journal of psychiatry, 2009, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Dis

2009
Personality disorders improve in patients treated for major depression.
    Acta psychiatrica Scandinavica, 2010, Volume: 122, Issue:3

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Comorbidity; Depressive Disorder, Major; Dose-Respon

2010
Adaptation of interpersonal psychotherapy to borderline personality disorder: a comparison of combined therapy and single pharmacotherapy.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2010, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Affective Symptoms; Antidepressive Agents, Second-Generation; Anxiety; Combined M

2010
Cognitive measures of adolescent depression: unique or unitary constructs?
    Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53, 2009, Volume: 38, Issue:6

    Topics: Adolescent; Child; Cognition Disorders; Cognitive Behavioral Therapy; Culture; Depressive Disorder,

2009
Does personality disorder co-morbidity impact treatment outcome for patients with major depression? A multi-level analysis.
    Journal of personality disorders, 2011, Volume: 25, Issue:1

    Topics: Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder, Major; Female; Fluoxetine;

2011
Personality predictors of antiaggressive response to fluoxetine: inverse association with neuroticism and harm avoidance.
    International clinical psychopharmacology, 2011, Volume: 26, Issue:5

    Topics: Adult; Aggression; Avoidance Learning; Fluoxetine; Harm Reduction; Humans; Male; Middle Aged; Neurot

2011
Comparison of the effects of fluoxetine, imipramine and placebo on personality in atypical depression.
    Journal of affective disorders, 2002, Volume: 71, Issue:1-3

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Child

2002
The relationship of personality disorders to treatment outcome in depressed outpatients.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:3

    Topics: Adult; Age Factors; Ambulatory Care; Antidepressive Agents; Chronic Disease; Comorbidity; Depressive

2003
Polymorphisms of DRD4 and DRD3 and risk of avoidant and obsessive personality traits and disorders.
    Psychiatry research, 2003, Jul-15, Volume: 119, Issue:1-2

    Topics: Adult; Alleles; Character; Exons; Exploratory Behavior; Female; Fluoxetine; Genotype; Humans; Male;

2003
Bipolar II disorder: personality and outcome in two clinical samples.
    The Australian and New Zealand journal of psychiatry, 2004, Volume: 38, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Adult; Bipolar Disorder; Bulimia; Cognitive Behavioral Therapy; Depres

2004
Problem-solving ability and comorbid personality disorders in depressed outpatients.
    Depression and anxiety, 2006, Volume: 23, Issue:8

    Topics: Adult; Antidepressive Agents, Second-Generation; Aptitude; Comorbidity; Depressive Disorder, Major;

2006
Dysfunctional attitudes and personality disorder comorbidity during long-term treatment of MDD.
    Depression and anxiety, 2007, Volume: 24, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Attitude; Cognition Disorders; Cognitive Behavioral

2007
Generalized social anxiety disorder and avoidant personality disorder: structural analysis and treatment outcome.
    Depression and anxiety, 2008, Volume: 25, Issue:5

    Topics: Activities of Daily Living; Adult; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbid

2008
Perceived stress and cognitive vulnerability mediate the effects of personality disorder comorbidity on treatment outcome in major depressive disorder: a path analysis study.
    The Journal of nervous and mental disease, 2007, Volume: 195, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Ambulatory Care; Cognition Disorders; Comorbidity; Depressive Diso

2007
Are study dropouts different from completers?
    Biological psychiatry, 1996, Oct-01, Volume: 40, Issue:7

    Topics: Adult; Antidepressive Agents, Second-Generation; Comorbidity; Depressive Disorder; Female; Fluoxetin

1996
Personality disorder scores improve with effective pharmacotherapy of depression.
    Journal of affective disorders, 1997, Volume: 43, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Ergolines; Female; Fluoxetine;

1997
Serotonin function and antiaggressive response to fluoxetine: a pilot study.
    Biological psychiatry, 1997, Oct-01, Volume: 42, Issue:7

    Topics: Adolescent; Adolescent Behavior; Adult; Aggression; Double-Blind Method; Fenfluramine; Fluoxetine; H

1997
Fluoxetine and impulsive aggressive behavior in personality-disordered subjects.
    Archives of general psychiatry, 1997, Volume: 54, Issue:12

    Topics: Adult; Aggression; Double-Blind Method; Fluoxetine; Humans; Impulsive Behavior; Male; Patient Dropou

1997
Divalproex sodium for impulsive aggressive behavior in patients with personality disorder.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:12

    Topics: Adult; Aggression; Anticonvulsants; Antimanic Agents; Female; Fluoxetine; Humans; Impulsive Behavior

1998

Other Studies

12 other studies available for fluoxetine and As If Personality

ArticleYear
Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine.
    Psychopharmacology, 2023, Volume: 240, Issue:2

    Topics: Aggression; Fluoxetine; Humans; Personality; Personality Disorders; Positron-Emission Tomography; Se

2023
Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder.
    Psychiatric genetics, 2010, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Aggression; Alleles; Female; Fluoxetine; Genotype; Humans; Impulsive Behavi

2010
Long-term follow-up of hypochondriasis after selective serotonin reuptake inhibitor treatment.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Aged; Child Abuse; Clinical Trials as Topic; Diagnostic and Statistical Manual of

2011
Personality disorders and depression.
    Psychological medicine, 2002, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cluster Analysis; Comorbidity; Depression; Female; F

2002
Temperament, childhood environment and psychopathology as risk factors for avoidant and borderline personality disorders.
    The Australian and New Zealand journal of psychiatry, 2003, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Borderline Personality Disorder; Child; Demography; Depressive Disorder, Major; F

2003
[Personality disorders and obsessive-compulsive disorder: critical analysis of the literature data and our studies].
    Minerva psichiatrica, 1995, Volume: 36, Issue:1

    Topics: Clomipramine; Comorbidity; Depressive Disorder; Fluoxetine; Humans; Obsessive-Compulsive Disorder; P

1995
Personality disorder comorbidity with major depression and response to fluoxetine treatment.
    Psychotherapy and psychosomatics, 1994, Volume: 62, Issue:3-4

    Topics: Adolescent; Adult; Aged; Cluster Analysis; Comorbidity; Depressive Disorder; Dose-Response Relations

1994
Anger attacks in unipolar depression, Part 1: Clinical correlates and response to fluoxetine treatment.
    The American journal of psychiatry, 1993, Volume: 150, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Anger; Comorbidity; Depressive Disorder; Diagnosis, Differ

1993
[Dysthymic disorder and its treatment].
    L'Encephale, 1993, Volume: 19 Spec No 2

    Topics: Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Fluoxetine; Humans; Personal

1993
Residual symptoms in depressed patients who respond acutely to fluoxetine.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:4

    Topics: Adult; Age of Onset; Ambulatory Care; Cognitive Behavioral Therapy; Comorbidity; Depressive Disorder

1999
Defense mechanisms and personality in depression.
    Depression and anxiety, 1999, Volume: 10, Issue:4

    Topics: Adult; Antidepressive Agents; Cyclohexanols; Defense Mechanisms; Depressive Disorder, Major; Female;

1999
Fluoxetine treatment of impulsive aggression in DSM-III-R personality disorder patients.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:5

    Topics: Adult; Aggression; Antisocial Personality Disorder; Borderline Personality Disorder; Disruptive, Imp

1990