fluoxetine has been researched along with Arrhythmias, Cardiac in 15 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine is frequently detected in aquatic environment, and chronic FLX exposure exhibits adverse effects on aquatic communities." | 5.62 | New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio). ( Chai, T; Cui, F; Di, S; Wang, X; Wu, S; Zhang, Y, 2021) |
| "Metal stress induced cardiac autonomic nerve and myocardial electrophysiological remodeling and ventricular arrhythmia in rats which could be significantly attenuated by fluoxetine in this model." | 3.77 | [Metal stress-induced arrhythmia and thoracic spinal cord 1-5 nerve remodeling and myocardial electrophysiological remodeling in rats]. ( Chen, H; Hou, YM; Hu, JL; Yan, Y; Yang, SL; Zhang, L; Zhou, QN, 2011) |
| "The association of migraine and depression has been confirmed in numerous studies and it has been suggested that both diseases influence each other in a bidirectional way." | 2.44 | [A clinical challenge. Pragmatic treatment of migraine and concomitant depression]. ( Jürgens, TP; Koch, HJ; Leinisch, E, 2008) |
| "Fluoxetine is frequently detected in aquatic environment, and chronic FLX exposure exhibits adverse effects on aquatic communities." | 1.62 | New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio). ( Chai, T; Cui, F; Di, S; Wang, X; Wu, S; Zhang, Y, 2021) |
| "Fluoxetine (Prozac) was more potent at blocking hERG 1a/1b than 1a channels, yielding a corresponding reduction in the safety margin." | 1.37 | hERG subunit composition determines differential drug sensitivity. ( Abi-Gerges, N; Holkham, H; Jones, EM; Pollard, CE; Robertson, GA; Valentin, JP, 2011) |
| "Each was an elderly white female with pulmonary disease and atrial arrhythmias, including atrial fibrillation, and each was prescribed diuretics, nitrates, and other cardiac and/or pulmonary agents." | 1.28 | Unexpected deaths in depressed medical inpatients treated with fluoxetine. ( Frontera, MA; Spier, SA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Chai, T | 1 |
| Cui, F | 1 |
| Di, S | 1 |
| Wu, S | 1 |
| Zhang, Y | 1 |
| Wang, X | 1 |
| Kermorgant, M | 1 |
| Lancien, F | 1 |
| Mimassi, N | 1 |
| Le Mével, JC | 1 |
| Abi-Gerges, N | 1 |
| Holkham, H | 1 |
| Jones, EM | 1 |
| Pollard, CE | 1 |
| Valentin, JP | 1 |
| Robertson, GA | 1 |
| Hu, JL | 1 |
| Zhou, QN | 1 |
| Yang, SL | 1 |
| Chen, H | 1 |
| Zhang, L | 1 |
| Yan, Y | 1 |
| Hou, YM | 1 |
| Henze, M | 1 |
| Tiniakov, R | 1 |
| Samarel, A | 1 |
| Holmes, E | 1 |
| Scrogin, K | 1 |
| Jürgens, TP | 1 |
| Leinisch, E | 1 |
| Koch, HJ | 1 |
| Stork, CM | 1 |
| Redd, JT | 1 |
| Fine, K | 1 |
| Hoffman, RS | 1 |
| D'Alonzo, AJ | 1 |
| Zhu, JL | 1 |
| Darbenzio, RB | 1 |
| Dorso, CR | 1 |
| Grover, GJ | 1 |
| Raviña, T | 1 |
| Suarez, ML | 1 |
| Mendez-Castrillón, J | 1 |
| Abebe-Campino, G | 1 |
| Offer, D | 1 |
| Stahl, B | 1 |
| Merlob, P | 1 |
| Spier, SA | 1 |
| Frontera, MA | 1 |
| Steiner, W | 1 |
| Fontaine, R | 1 |
| Fisch, C | 1 |
2 reviews available for fluoxetine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
[A clinical challenge. Pragmatic treatment of migraine and concomitant depression].
Topics: Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Antidepressive Ag | 2008 |
13 other studies available for fluoxetine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio).
Topics: Animals; Arrhythmias, Cardiac; Cardiotoxicity; Fluoxetine; Stereoisomerism; Zebrafish | 2021 |
Central actions of serotonin and fluoxetine on the QT interval of the electrocardiogram in trout.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Drug Administration Routes; Electrocardi | 2015 |
hERG subunit composition determines differential drug sensitivity.
Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line, Transformed; Drug Evaluation, Preclinical; Ether | 2011 |
[Metal stress-induced arrhythmia and thoracic spinal cord 1-5 nerve remodeling and myocardial electrophysiological remodeling in rats].
Topics: Animals; Arrhythmias, Cardiac; Choline O-Acetyltransferase; Fluoxetine; GAP-43 Protein; Male; Rats; | 2011 |
Chronic fluoxetine reduces autonomic control of cardiac rhythms in rats with congestive heart failure.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Catecholamines; Coronary Ve | 2013 |
Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Dextropropoxyphene; Drug Interactions | 1995 |
Proarrhythmic effects of pinacidil are partially mediated through enhancement of catecholamine release in isolated perfused guinea-pig hearts.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Card | 1998 |
Fluoxetine-induced QTU interval prolongation, T wave alternans and syncope.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Fluoxetine; Humans; Middle Aged; Selective Seroto | 1998 |
Cardiac arrhythmia in a newborn infant associated with fluoxetine use during pregnancy.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Fluoxetine; Humans; Infant, Newborn; Male; Matern | 2002 |
Unexpected deaths in depressed medical inpatients treated with fluoxetine.
Topics: Aged; Arrhythmias, Cardiac; Death, Sudden; Depressive Disorder; Female; Fluoxetine; Humans; Inpatien | 1991 |
Toxic reaction following the combined administration of fluoxetine and L-tryptophan: five case reports.
Topics: Adult; Akathisia, Drug-Induced; Arrhythmias, Cardiac; Drug Interactions; Female; Fluoxetine; Humans; | 1986 |
Effect of fluoxetine on the electrocardiogram.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch | 1985 |