fluoxetine has been researched along with Arrhythmia in 15 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine is frequently detected in aquatic environment, and chronic FLX exposure exhibits adverse effects on aquatic communities." | 5.62 | New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio). ( Chai, T; Cui, F; Di, S; Wang, X; Wu, S; Zhang, Y, 2021) |
| "Metal stress induced cardiac autonomic nerve and myocardial electrophysiological remodeling and ventricular arrhythmia in rats which could be significantly attenuated by fluoxetine in this model." | 3.77 | [Metal stress-induced arrhythmia and thoracic spinal cord 1-5 nerve remodeling and myocardial electrophysiological remodeling in rats]. ( Chen, H; Hou, YM; Hu, JL; Yan, Y; Yang, SL; Zhang, L; Zhou, QN, 2011) |
| "The association of migraine and depression has been confirmed in numerous studies and it has been suggested that both diseases influence each other in a bidirectional way." | 2.44 | [A clinical challenge. Pragmatic treatment of migraine and concomitant depression]. ( Jürgens, TP; Koch, HJ; Leinisch, E, 2008) |
| "Fluoxetine is frequently detected in aquatic environment, and chronic FLX exposure exhibits adverse effects on aquatic communities." | 1.62 | New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio). ( Chai, T; Cui, F; Di, S; Wang, X; Wu, S; Zhang, Y, 2021) |
| "Fluoxetine (Prozac) was more potent at blocking hERG 1a/1b than 1a channels, yielding a corresponding reduction in the safety margin." | 1.37 | hERG subunit composition determines differential drug sensitivity. ( Abi-Gerges, N; Holkham, H; Jones, EM; Pollard, CE; Robertson, GA; Valentin, JP, 2011) |
| "Each was an elderly white female with pulmonary disease and atrial arrhythmias, including atrial fibrillation, and each was prescribed diuretics, nitrates, and other cardiac and/or pulmonary agents." | 1.28 | Unexpected deaths in depressed medical inpatients treated with fluoxetine. ( Frontera, MA; Spier, SA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Chai, T | 1 |
| Cui, F | 1 |
| Di, S | 1 |
| Wu, S | 1 |
| Zhang, Y | 1 |
| Wang, X | 1 |
| Kermorgant, M | 1 |
| Lancien, F | 1 |
| Mimassi, N | 1 |
| Le Mével, JC | 1 |
| Abi-Gerges, N | 1 |
| Holkham, H | 1 |
| Jones, EM | 1 |
| Pollard, CE | 1 |
| Valentin, JP | 1 |
| Robertson, GA | 1 |
| Hu, JL | 1 |
| Zhou, QN | 1 |
| Yang, SL | 1 |
| Chen, H | 1 |
| Zhang, L | 1 |
| Yan, Y | 1 |
| Hou, YM | 1 |
| Henze, M | 1 |
| Tiniakov, R | 1 |
| Samarel, A | 1 |
| Holmes, E | 1 |
| Scrogin, K | 1 |
| Jürgens, TP | 1 |
| Leinisch, E | 1 |
| Koch, HJ | 1 |
| Stork, CM | 1 |
| Redd, JT | 1 |
| Fine, K | 1 |
| Hoffman, RS | 1 |
| D'Alonzo, AJ | 1 |
| Zhu, JL | 1 |
| Darbenzio, RB | 1 |
| Dorso, CR | 1 |
| Grover, GJ | 1 |
| Raviña, T | 1 |
| Suarez, ML | 1 |
| Mendez-Castrillón, J | 1 |
| Abebe-Campino, G | 1 |
| Offer, D | 1 |
| Stahl, B | 1 |
| Merlob, P | 1 |
| Spier, SA | 1 |
| Frontera, MA | 1 |
| Steiner, W | 1 |
| Fontaine, R | 1 |
| Fisch, C | 1 |
2 reviews available for fluoxetine and Arrhythmia
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
[A clinical challenge. Pragmatic treatment of migraine and concomitant depression].
Topics: Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Antidepressive Ag | 2008 |
13 other studies available for fluoxetine and Arrhythmia
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio).
Topics: Animals; Arrhythmias, Cardiac; Cardiotoxicity; Fluoxetine; Stereoisomerism; Zebrafish | 2021 |
Central actions of serotonin and fluoxetine on the QT interval of the electrocardiogram in trout.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Drug Administration Routes; Electrocardi | 2015 |
hERG subunit composition determines differential drug sensitivity.
Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line, Transformed; Drug Evaluation, Preclinical; Ether | 2011 |
[Metal stress-induced arrhythmia and thoracic spinal cord 1-5 nerve remodeling and myocardial electrophysiological remodeling in rats].
Topics: Animals; Arrhythmias, Cardiac; Choline O-Acetyltransferase; Fluoxetine; GAP-43 Protein; Male; Rats; | 2011 |
Chronic fluoxetine reduces autonomic control of cardiac rhythms in rats with congestive heart failure.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Catecholamines; Coronary Ve | 2013 |
Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Dextropropoxyphene; Drug Interactions | 1995 |
Proarrhythmic effects of pinacidil are partially mediated through enhancement of catecholamine release in isolated perfused guinea-pig hearts.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Card | 1998 |
Fluoxetine-induced QTU interval prolongation, T wave alternans and syncope.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Fluoxetine; Humans; Middle Aged; Selective Seroto | 1998 |
Cardiac arrhythmia in a newborn infant associated with fluoxetine use during pregnancy.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Fluoxetine; Humans; Infant, Newborn; Male; Matern | 2002 |
Unexpected deaths in depressed medical inpatients treated with fluoxetine.
Topics: Aged; Arrhythmias, Cardiac; Death, Sudden; Depressive Disorder; Female; Fluoxetine; Humans; Inpatien | 1991 |
Toxic reaction following the combined administration of fluoxetine and L-tryptophan: five case reports.
Topics: Adult; Akathisia, Drug-Induced; Arrhythmias, Cardiac; Drug Interactions; Female; Fluoxetine; Humans; | 1986 |
Effect of fluoxetine on the electrocardiogram.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch | 1985 |