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fluoxetine and Anorexia

fluoxetine has been researched along with Anorexia in 26 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine is an anorexic agent known to reduce food intake and weight gain."5.33Role of neuropeptide Y and proopiomelanocortin in fluoxetine-induced anorexia. ( Choi, SH; Jahng, JW; Kim, BT; Lee, SY; Myung, CS; Song, GY, 2005)
"Fluoxetine treatment did not affect the 5-HT effect on food intake amount but significantly reduced the 5-HT effect on feeding latency."5.33Chronic fluoxetine administration desensitizes the hyperglycemia but not the anorexia induced by serotonin in rats receiving fructose-enriched chow. ( Cheng, JT; Chung, HH; Hsiao, SH; Tong, YC, 2006)
" In contrast, activation of somatodendritc 5-HT(1A) receptors in the raphe nuclei reduces forebrain 5-HT bioavailability and agonists of these receptors, including 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), reliably stimulate eating behavior."5.32Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT. ( Braver, M; Currie, PJ; Mirza, A; Sricharoon, K, 2004)
"This study evaluated the efficacy of nutritional management with and without fluoxetine (FLX) in anorexia nervosa diagnosed according to Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria."3.72Nutritional management of anorexic patients with and without fluoxetine: 1-year follow-up. ( Cavagnini, F; Dipasquale, S; Malvini, L; Mauri, MC; Omboni, AC; Pasqualinotto, L; Redaelli, G; Ruggiero, GM; Volonteri, LS, 2003)
"We examined the effect of fluoxetine to suppress binge eating in rats with a history of caloric restriction (CR) and the extent to which this effect was altered by stress and hunger."3.72Stress and hunger alter the anorectic efficacy of fluoxetine in binge-eating rats with a history of caloric restriction. ( Boggiano, MM; Chandler, PC; Maldonado, C; Oswald, KD; Placidi, RJ; Wauford, PK, 2004)
"To assess whether fluoxetine use is associated with significant weight loss or other side effects in depressed elderly patients with concomitant medical illness."3.68Fluoxetine in elderly patients: is there cause for concern? ( Brymer, C; Winograd, CH, 1992)
"Fluoxetine is an anorexic agent known to reduce food intake and weight gain."1.33Role of neuropeptide Y and proopiomelanocortin in fluoxetine-induced anorexia. ( Choi, SH; Jahng, JW; Kim, BT; Lee, SY; Myung, CS; Song, GY, 2005)
"Fluoxetine treatment did not affect the 5-HT effect on food intake amount but significantly reduced the 5-HT effect on feeding latency."1.33Chronic fluoxetine administration desensitizes the hyperglycemia but not the anorexia induced by serotonin in rats receiving fructose-enriched chow. ( Cheng, JT; Chung, HH; Hsiao, SH; Tong, YC, 2006)
" In contrast, activation of somatodendritc 5-HT(1A) receptors in the raphe nuclei reduces forebrain 5-HT bioavailability and agonists of these receptors, including 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), reliably stimulate eating behavior."1.32Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT. ( Braver, M; Currie, PJ; Mirza, A; Sricharoon, K, 2004)
"Treatment with fenfluramine or fluoxetine increased post-fasting anorexia, abolished the preference for carbohydrates and decreased lipid intake."1.29Effect of activation of the serotoninergic system during prolonged starvation on subsequent caloric intake and macronutrient selection in the Zucker rat. ( Duhault, J; Espinal, J; Lacour, F; Rolland, Y, 1993)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (42.31)18.2507
2000's10 (38.46)29.6817
2010's5 (19.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, ZA1
Mu, W1
Osborne, LM1
Cordner, ZA1
Amin, R1
Zarate, J1
Churruca, I1
Pascual, J1
Casis, L1
Sallés, J1
Echevarría, E1
Miryala, CS1
Maswood, N1
Uphouse, L1
Klenotich, SJ1
Seiglie, MP1
McMurray, MS1
Roitman, JD1
Le Grange, D1
Dugad, P1
Dulawa, SC1
Lauzurica, N1
García-García, L1
Fuentes, JA1
Delgado, M1
Merali, Z1
Brennan, K1
Brau, P1
Anisman, H1
Ruggiero, GM1
Mauri, MC1
Omboni, AC1
Volonteri, LS1
Dipasquale, S1
Malvini, L1
Redaelli, G1
Pasqualinotto, L1
Cavagnini, F1
Currie, PJ2
Braver, M1
Mirza, A1
Sricharoon, K1
Placidi, RJ1
Chandler, PC1
Oswald, KD1
Maldonado, C1
Wauford, PK1
Boggiano, MM1
Myung, CS1
Kim, BT1
Choi, SH1
Song, GY1
Lee, SY1
Jahng, JW1
Hsiao, SH1
Chung, HH1
Tong, YC1
Cheng, JT1
Fountoulakis, KN1
Iacovides, A1
Siamouli, M1
Koumaris, V1
Kaprinis, GS1
Mattioli, L1
Perfumi, M1
McCann, UD1
Yuan, J2
Ricaurte, GA2
Vaz, FJ1
Salcedo, MS1
Porterfield, LM1
Lauterio, TJ2
Rieg, TS2
Ahmed, I2
Aravich, PF2
Duhault, J1
Lacour, F1
Espinal, J1
Rolland, Y1
Black, PN1
Menting, JE1
Honig, A1
Verhey, FR1
Hartmans, M1
Rozendaal, N1
de Vet, HC1
van Praag, HM1
Clifton, PG1
Lee, MD1
Coscina, DV1
Fletcher, PJ1
Callahan, BT1
Brymer, C1
Winograd, CH1

Reviews

1 review available for fluoxetine and Anorexia

ArticleYear
Fluoxetine hypophagia. Is there a role for serotonergic mechanisms in some circumstances?
    Trends in pharmacological sciences, 1997, Volume: 18, Issue:6

    Topics: Animals; Anorexia; Antidepressive Agents, Second-Generation; Eating; Fluoxetine; Rats; Selective Ser

1997

Other Studies

25 other studies available for fluoxetine and Anorexia

ArticleYear
Eighteen-year-old man with autism, obsessive compulsive disorder and a
    BMJ case reports, 2018, Jul-09, Volume: 2018

    Topics: Adolescent; Anorexia; Autistic Disorder; Fluoxetine; Humans; Male; Nerve Tissue Proteins; Obsessive-

2018
Fluoxetine and Trazodone Combination Pharmacotherapy Resulting in Severe Irritability, Anger, Anxiety, and Anorexia: Probable Adverse Drug Interaction.
    The primary care companion for CNS disorders, 2016, Aug-11, Volume: 18, Issue:4

    Topics: Adult; Anger; Anorexia; Antidepressive Agents, Second-Generation; Anxiety; Drug Interactions; Drug T

2016
Brain endocannabinoid system is involved in fluoxetine-induced anorexia.
    Nutritional neuroscience, 2008, Volume: 11, Issue:3

    Topics: Animals; Anorexia; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Corpus Striatum; Endocan

2008
Fluoxetine prevents 8-OH-DPAT-induced hyperphagia in Fischer inbred rats.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Eating; Estradiol; Female; Fluoxetine; Hy

2011
Olanzapine, but not fluoxetine, treatment increases survival in activity-based anorexia in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:7

    Topics: Animals; Anorexia; Benzodiazepines; Body Weight; Disease Models, Animal; Dose-Response Relationship,

2012
Hypophagia and induction of serotonin transporter gene expression in raphe nuclei of male and female rats after short-term fluoxetine treatment.
    Journal of physiology and biochemistry, 2013, Volume: 69, Issue:1

    Topics: Animals; Anorexia; Body Weight; Eating; Female; Fluoxetine; Gene Expression; Humans; Injections, Int

2013
Dissociating anorexia and anhedonia elicited by interleukin-1beta: antidepressant and gender effects on responding for "free chow" and "earned" sucrose intake.
    Psychopharmacology, 2003, Volume: 165, Issue:4

    Topics: Animals; Anorexia; Antidepressive Agents; Conditioning, Operant; Eating; Female; Fluoxetine; Injecti

2003
Nutritional management of anorexic patients with and without fluoxetine: 1-year follow-up.
    Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:3

    Topics: Adult; Analysis of Variance; Anorexia; Body Mass Index; Female; Fluoxetine; Follow-Up Studies; Human

2003
Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT.
    Psychopharmacology, 2004, Volume: 172, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Dose-Response Relationship, Drug; Feeding

2004
Stress and hunger alter the anorectic efficacy of fluoxetine in binge-eating rats with a history of caloric restriction.
    The International journal of eating disorders, 2004, Volume: 36, Issue:3

    Topics: Animals; Anorexia; Bulimia; Energy Intake; Female; Fluoxetine; Hunger; Injections, Intraperitoneal;

2004
Role of neuropeptide Y and proopiomelanocortin in fluoxetine-induced anorexia.
    Archives of pharmacal research, 2005, Volume: 28, Issue:6

    Topics: Animals; Anorexia; Appetite Regulation; Arcuate Nucleus of Hypothalamus; Autoradiography; Body Weigh

2005
Chronic fluoxetine administration desensitizes the hyperglycemia but not the anorexia induced by serotonin in rats receiving fructose-enriched chow.
    Neuroscience letters, 2006, Aug-14, Volume: 404, Issue:1-2

    Topics: Animal Feed; Animals; Anorexia; Body Weight; Energy Intake; Feeding Behavior; Fluoxetine; Fructose;

2006
Successful treatment of anorexia with a combination of high-dose olanzapine, fluoxetine and mirtazapine.
    International journal of clinical pharmacology and therapeutics, 2006, Volume: 44, Issue:9

    Topics: Adult; Anorexia; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsy

2006
Rhodiola rosea L. extract reduces stress- and CRF-induced anorexia in rats.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:7

    Topics: Animals; Anorexia; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Escherichia co

2007
Fenfluramine's appetite suppression and serotonin neurotoxicity are separable.
    European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3

    Topics: Animals; Anorexia; Appetite; Body Weight; Drug Combinations; Eating; Fenfluramine; Fluoxetine; Male;

1995
Fluoxetine-induced anorexia in a bulimic patient with antecedents of anorexia nervosa.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:3

    Topics: Adult; Anorexia; Anorexia Nervosa; Bulimia; Drug Administration Schedule; Female; Fluoxetine; Humans

1994
If weight loss persists after other symptoms of depression subside.
    RN, 1994, Volume: 57, Issue:8

    Topics: Anorexia; Depressive Disorder; Female; Fluoxetine; Humans; Middle Aged; Weight Loss

1994
Fluoxetine induced insulin-like growth factor II (IGF-II) changes in hypothalami of normal, exercised and food restricted rats.
    Regulatory peptides, 1993, Oct-20, Volume: 48, Issue:1-2

    Topics: Animals; Anorexia; Blood Glucose; Feeding Behavior; Fluoxetine; Hypothalamus; Insulin; Insulin-Like

1993
Fluoxetine induces thymus oxytocin abnormalities in activity-based anorexia.
    Annals of the New York Academy of Sciences, 1993, Jul-22, Volume: 689

    Topics: Animals; Anorexia; Fluoxetine; Male; Oxytocin; Physical Exertion; Rats; Rats, Sprague-Dawley; Thymus

1993
Effect of activation of the serotoninergic system during prolonged starvation on subsequent caloric intake and macronutrient selection in the Zucker rat.
    Appetite, 1993, Volume: 20, Issue:2

    Topics: Animals; Anorexia; Dietary Carbohydrates; Energy Intake; Fenfluramine; Fluoxetine; Food Preferences;

1993
Probable interaction between fluoxetine and itraconazole.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:10

    Topics: Adult; Anorexia; Antifungal Agents; Drug Interactions; Fluoxetine; Humans; Itraconazole; Male; Selec

1995
Selective serotonin reuptake inhibitors (SSRIs) in the treatment of elderly depressed patients: a qualitative analysis of the literature on their efficacy and side-effects.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:3

    Topics: 1-Naphthylamine; Aged; Anorexia; Antidepressive Agents; Depressive Disorder; Diarrhea; Fluoxetine; F

1996
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
    Brain research, 1998, Jul-27, Volume: 800, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus St

1998
Fluoxetine increases the anorectic and long-term dopamine-depleting effects of phentermine.
    Synapse (New York, N.Y.), 2000, Dec-15, Volume: 38, Issue:4

    Topics: Animals; Anorexia; Appetite Depressants; Biogenic Monoamines; Body Temperature; Body Weight; Brain;

2000
Fluoxetine in elderly patients: is there cause for concern?
    Journal of the American Geriatrics Society, 1992, Volume: 40, Issue:9

    Topics: Age Factors; Aged; Ambulatory Care; Anorexia; Comorbidity; Depressive Disorder; Female; Fluoxetine;

1992