Page last updated: 2024-10-27

fluoxetine and Amblyopia

fluoxetine has been researched along with Amblyopia in 4 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Amblyopia: A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.

Research Excerpts

ExcerptRelevanceReference
"Amblyopia is a common visual disorder that is treatable in childhood."6.87Fluoxetine does not enhance the effect of perceptual learning on visual function in adults with amblyopia. ( Booms, S; Castrén, E; Huttunen, HJ; Karvonen, E; Latvala, ML; Liinamaa, J; Lindberg, L; Palva, JM; Palva, S; Saarela, V; Uusitalo, H, 2018)
"In this double-blinded, randomized, controlled trial (IRCT2016052428046N1; registered retrospectively), 40 eligible participants with anisometropic or mixed amblyopia were randomly assigned to either fluoxetine or placebo groups."5.30Oral fluoxetine in the management of amblyopic patients aged between 10 and 40 years old: a randomized clinical trial. ( Khalili, MR; Nowroozzadeh, MH; Rastegar, K; Sharif, MH; Talebnejad, MR, 2019)
"Amblyopia is a common visual disorder that is treatable in childhood."2.87Fluoxetine does not enhance the effect of perceptual learning on visual function in adults with amblyopia. ( Booms, S; Castrén, E; Huttunen, HJ; Karvonen, E; Latvala, ML; Liinamaa, J; Lindberg, L; Palva, JM; Palva, S; Saarela, V; Uusitalo, H, 2018)
"Amblyopia is a developmental brain disorder in which vision is lost due to asymmetric or inadequate visual stimulation early in life."2.53Medical Therapies of Amblyopia: Translational Research to Expand Our Treatment Armamentarium. ( Gore, C; Wu, C, 2016)
" We found that chronic administration of fluoxetine reinstates ocular dominance plasticity in adulthood and promotes the recovery of visual functions in adult amblyopic animals, as tested electrophysiologically and behaviorally."1.35The antidepressant fluoxetine restores plasticity in the adult visual cortex. ( Baroncelli, L; Castrén, E; De Pasquale, R; Maffei, L; Maya Vetencourt, JF; O'Leary, OF; Sale, A; Viegi, A, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huttunen, HJ1
Palva, JM1
Lindberg, L1
Palva, S1
Saarela, V1
Karvonen, E1
Latvala, ML1
Liinamaa, J1
Booms, S1
Castrén, E2
Uusitalo, H1
Sharif, MH1
Talebnejad, MR1
Rastegar, K1
Khalili, MR1
Nowroozzadeh, MH1
Gore, C1
Wu, C1
Maya Vetencourt, JF1
Sale, A1
Viegi, A1
Baroncelli, L1
De Pasquale, R1
O'Leary, OF1
Maffei, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
FLOW Trial: Fluoxetine to Open the Critical Period Time Window to Improve Motor Recovery After Stroke[NCT03448159]Phase 252 participants (Actual)Interventional2019-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fluoxetine and Amblyopia

ArticleYear
Medical Therapies of Amblyopia: Translational Research to Expand Our Treatment Armamentarium.
    Seminars in ophthalmology, 2016, Volume: 31, Issue:1-2

    Topics: Amblyopia; Carbidopa; Cholinesterase Inhibitors; Donepezil; Dopamine Agonists; Drug Combinations; Fl

2016

Trials

2 trials available for fluoxetine and Amblyopia

ArticleYear
Fluoxetine does not enhance the effect of perceptual learning on visual function in adults with amblyopia.
    Scientific reports, 2018, 08-27, Volume: 8, Issue:1

    Topics: Adult; Amblyopia; Female; Fluoxetine; Humans; Learning; Male; Middle Aged; Treatment Outcome; Vision

2018
Oral fluoxetine in the management of amblyopic patients aged between 10 and 40 years old: a randomized clinical trial.
    Eye (London, England), 2019, Volume: 33, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Amblyopia; Child; Dose-Response Relationship, Drug; Double-

2019

Other Studies

1 other study available for fluoxetine and Amblyopia

ArticleYear
The antidepressant fluoxetine restores plasticity in the adult visual cortex.
    Science (New York, N.Y.), 2008, Apr-18, Volume: 320, Issue:5874

    Topics: Amblyopia; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Dia

2008