Page last updated: 2024-10-27

fluoxetine and Allergic Encephalomyelitis

fluoxetine has been researched along with Allergic Encephalomyelitis in 4 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"This study was carried out to clarify the effects of the antidepressant fluoxetine, a selective serotonin reuptake inhibitor, for its potential use in autoimmune diseases like multiple sclerosis in a rat model of experimental autoimmune encephalomyelitis (EAE)."3.78Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats. ( Liu, S; Liu, XJ; Lu, T; Qiu, G; Wang, X; Wu, Y; Yuan, XQ, 2012)
"The mice with experimental autoimmune encephalomyelitis exhibited exaggerated grooming activity."1.48Auto-Reactive Th17-Cells Trigger Obsessive-Compulsive-Disorder Like Behavior in Mice With Experimental Autoimmune Encephalomyelitis. ( Kant, R; Pasi, S; Surolia, A, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Akhavan Tavakoli, M1
Soleimani, M1
Marzban, H1
Shabani, R1
Moradi, F1
Ajdary, M1
Mehdizadeh, M1
Bhat, R1
Mahapatra, S1
Axtell, RC1
Steinman, L1
Kant, R1
Pasi, S1
Surolia, A1
Yuan, XQ1
Qiu, G1
Liu, XJ1
Liu, S1
Wu, Y1
Wang, X1
Lu, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
5-HTSEP: Serotonin 5-HT7 Receptor Implication in the Inflammatory Mechanisms in Multiple Sclerosis[NCT04546698]78 participants (Actual)Observational2020-09-07Completed
RESEPTOR 5-HT7 : Interest of the 5-HT7 Serotonin Receptor as a Biomarker in Multiple Sclerosis[NCT05746845]120 participants (Anticipated)Observational2023-03-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for fluoxetine and Allergic Encephalomyelitis

ArticleYear
Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine.
    Molecular neurobiology, 2023, Volume: 60, Issue:4

    Topics: Animals; Autophagy; bcl-2-Associated X Protein; Cannabidiol; Cerebellum; Encephalomyelitis, Autoimmu

2023
Amelioration of ongoing experimental autoimmune encephalomyelitis with fluoxetine.
    Journal of neuroimmunology, 2017, 12-15, Volume: 313

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; CD11b Antigen; Cell Death; Cell Proliferation; Cytokin

2017
Auto-Reactive Th17-Cells Trigger Obsessive-Compulsive-Disorder Like Behavior in Mice With Experimental Autoimmune Encephalomyelitis.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adoptive Transfer; Animals; Autoimmunity; Behavior, Animal; Disease Models, Animal; Encephalomyeliti

2018
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
    Neuroimmunomodulation, 2012, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema

2012
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
    Neuroimmunomodulation, 2012, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema

2012
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
    Neuroimmunomodulation, 2012, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema

2012
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
    Neuroimmunomodulation, 2012, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema

2012