fluoxetine has been researched along with Aggression in 142 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The intent of this study was to compare the efficacy and safety of fluoxetine, olanzapine, or the olanzapine-fluoxetine combination (OFC) in the treatment of women meeting criteria for borderline personality disorder (without concurrent major depressive disorder)." | 9.11 | A preliminary, randomized trial of fluoxetine, olanzapine, and the olanzapine-fluoxetine combination in women with borderline personality disorder. ( Frankenburg, FR; Parachini, EA; Zanarini, MC, 2004) |
| "Nineteen mentally retarded inpatients with epilepsy and a history of current or recent aggressive behavior were treated with 20 mg of fluoxetine daily." | 9.08 | Effects of fluoxetine on aggressive behavior of adult inpatients with mental retardation and epilepsy. ( Ciani, N; Nuccetelli, F; Pasini, A; Troisi, A; Vicario, E, 1995) |
| "Fluoxetine may be useful in the management of dominance aggression in dogs." | 9.08 | Use of fluoxetine to treat dominance aggression in dogs. ( Dodman, NH; Donnelly, R; Mertens, P; Miczek, K; Rand, W; Shuster, L, 1996) |
| "This meta-analysis assessed aggression and/or hostility-related events in children and adolescents treated with fluoxetine (n = 376) compared with placebo (n = 255)." | 8.84 | Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo. ( Allen, AJ; Caldwell, C; Nilsson, M; Plewes, J; Tauscher-Wisniewski, S, 2007) |
| "A comprehensive meta-analysis was performed to address the possible association of fluoxetine with violence or aggression." | 8.78 | Fluoxetine not associated with increased aggression in controlled clinical trials. ( Beasley, CM; Heiligenstein, JH; Potvin, JH, 1993) |
| "The aim of this study is to identify associations between regional serotonin transporter (5-HTT) availability and trait and state aggression, as well as response to the anti-aggressive effects of fluoxetine." | 8.31 | Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine. ( Abi-Dargham, A; Carson, RE; Hazlett, EA; Huang, Y; Koenigsberg, HW; McClure, MM; Nabulsi, N; New, AS; Perez-Rodriguez, MM; Rosell, DR; Siever, LS; Slifstein, M; Thompson, J; Xu, X, 2023) |
| " Regular use of fluoxetine apparently prevented the onset of anxiety, depression, aggressiveness, and suicide ideation, even with the concurrent use of AAS." | 8.02 | Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids. ( Amaral, JMX; Aquino Neto, FR; Baker, JS; Chagas, SV; Cruz, MS; Mullen, C; Padilha, MC; Vieira Neto, L, 2021) |
| " Using the selective serotonin reuptake inhibitor fluoxetine, we examined the impact of 10μmol exposures on associative learning and aggression between mirror and conspecific social reinforcers." | 7.85 | Of fish and mirrors: Fluoxetine disrupts aggression and learning for social rewards. ( Eisenreich, BR; Greene, S; Szalda-Petree, A, 2017) |
| "The following study set out to test the hypothesis that acute treatment with the selective serotonin reuptake inhibitor, fluoxetine, would result in a rise in circulating 5-HT levels and consequently a decrease in territorial aggression in the Gulf toadfish, Opsanus beta." | 7.77 | Higher levels of aggression are observed in socially dominant toadfish treated with the selective serotonin reuptake inhibitor, fluoxetine. ( Gonzalez, A; McDonald, MD; Sloman, KA, 2011) |
| "Studies using dopaminergic and serotonergic agonists or antagonists implicate involvement of these systems in various aspects of early maternal behavior and postpartum aggression towards an intruder in rats, both of which are associated with the presence of oxytocin in specific brain regions." | 7.73 | The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat. ( Elliott, DL; Greenhill, KW; Hofler, VE; Johns, JM; Joyner, PW; Knupp, K; Lomas, LM; McMurray, MS; Middleton, CL; Walker, CH, 2005) |
| "Malnutrition effect during the suckling period on aggressive behavior was investigated in adult rats treated and not treated with fluoxetine, a selective serotonin reuptake inhibitor." | 7.72 | Malnutrition during brain growth spurt alters the effect of fluoxetine on aggressive behavior in adult rats. ( Barreto-Medeiros, JM; Cabral-Filho, JE; De-Castro, CM; Feitoza, EG; Magalhaes, K; Manhaes-De-Castro, FM; Manhaes-De-Castro, R, 2004) |
| "Fluoxetine-treated patients (n=13) did not differ from placebo-treated patients (n=13) on any key demographic or behavioral variables." | 6.73 | Placebo-controlled, randomized trial of fluoxetine in the treatment of aggression in male intimate partner abusers. ( Coccaro, EF; Kavoussi, RJ; Lee, R, 2008) |
| " An analogous potentiation of clonidine-induced aggressiveness was obtained with chronic administration (the schedule as above) of levomepromazine (2 mg/kg) or thioridazine (5 mg/kg) but not of spiperone (0." | 5.26 | Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. ( Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E, 1981) |
| "The intent of this study was to compare the efficacy and safety of fluoxetine, olanzapine, or the olanzapine-fluoxetine combination (OFC) in the treatment of women meeting criteria for borderline personality disorder (without concurrent major depressive disorder)." | 5.11 | A preliminary, randomized trial of fluoxetine, olanzapine, and the olanzapine-fluoxetine combination in women with borderline personality disorder. ( Frankenburg, FR; Parachini, EA; Zanarini, MC, 2004) |
| "Nineteen mentally retarded inpatients with epilepsy and a history of current or recent aggressive behavior were treated with 20 mg of fluoxetine daily." | 5.08 | Effects of fluoxetine on aggressive behavior of adult inpatients with mental retardation and epilepsy. ( Ciani, N; Nuccetelli, F; Pasini, A; Troisi, A; Vicario, E, 1995) |
| "Fluoxetine, but not placebo, treatment resulted in a sustained reduction in scores on the Irritability and Aggression subscales of the Overt Aggression Scale-Modified for Outpatients that was first apparent during months 2 and 3 of treatment, respectively." | 5.08 | Fluoxetine and impulsive aggressive behavior in personality-disordered subjects. ( Coccaro, EF; Kavoussi, RJ, 1997) |
| "This meta-analysis assessed aggression and/or hostility-related events in children and adolescents treated with fluoxetine (n = 376) compared with placebo (n = 255)." | 4.84 | Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo. ( Allen, AJ; Caldwell, C; Nilsson, M; Plewes, J; Tauscher-Wisniewski, S, 2007) |
| "A comprehensive meta-analysis was performed to address the possible association of fluoxetine with violence or aggression." | 4.78 | Fluoxetine not associated with increased aggression in controlled clinical trials. ( Beasley, CM; Heiligenstein, JH; Potvin, JH, 1993) |
| "The aim of this study is to identify associations between regional serotonin transporter (5-HTT) availability and trait and state aggression, as well as response to the anti-aggressive effects of fluoxetine." | 4.31 | Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine. ( Abi-Dargham, A; Carson, RE; Hazlett, EA; Huang, Y; Koenigsberg, HW; McClure, MM; Nabulsi, N; New, AS; Perez-Rodriguez, MM; Rosell, DR; Siever, LS; Slifstein, M; Thompson, J; Xu, X, 2023) |
| " Regular use of fluoxetine apparently prevented the onset of anxiety, depression, aggressiveness, and suicide ideation, even with the concurrent use of AAS." | 4.02 | Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids. ( Amaral, JMX; Aquino Neto, FR; Baker, JS; Chagas, SV; Cruz, MS; Mullen, C; Padilha, MC; Vieira Neto, L, 2021) |
| " Using the selective serotonin reuptake inhibitor fluoxetine, we examined the impact of 10μmol exposures on associative learning and aggression between mirror and conspecific social reinforcers." | 3.85 | Of fish and mirrors: Fluoxetine disrupts aggression and learning for social rewards. ( Eisenreich, BR; Greene, S; Szalda-Petree, A, 2017) |
| " To this end, pregnant female dams were exposed to saline or fluoxetine (FLX) throughout pregnancy, and the behavior of the offspring was examined." | 3.83 | Prenatal exposure to selective serotonin reuptake inhibitors (SSRI) increases aggression and modulates maternal behavior in offspring mice. ( Avitsur, R; Levy, S; Svirsky, N, 2016) |
| " The selective serotonin reuptake inhibitor fluoxetine (Prozac) has been reported to affect diverse behaviours (feeding, aggression, and reproduction) and also the endocrine system (steroid biosynthesis pathway) in fish." | 3.81 | Prozac affects stickleback nest quality without altering androgen, spiggin or aggression levels during a 21-day breeding test. ( Elphinstone Davis, J; Hatfield, R; Katsiadaki, I; Sebire, M; Winberg, S, 2015) |
| "The effectiveness of clorazepate dipotassium combined with fluoxetine and a behaviour modification programme for the treatment of anxiety disorders in dogs was investigated." | 3.80 | Fluoxetine combined with clorazepate dipotassium and behaviour modification for treatment of anxiety-related disorders in dogs. ( Anzola, B; Ibáñez, M; Olivares, A; Pineda, S, 2014) |
| "A Commentary published in the October 2012 issue of Behavioral Neuroscience entitled "SSRIs, Adolescents, and Aggression: Tempering Human Implications Regarding SSRI-Induced Aggression in Hamsters: Comment on Ricci and Melloni (2012)", presents an interpretation of findings from our report published in the same issue of Behavioral Neuroscience entitled "Repeated Fluoxetine Administration During Adolescence Stimulates Aggressive Behavior and Alters Serotonin and Vasopressin Neural Development in Hamsters"." | 3.79 | Preclinical investigations into the relationship between adolescent SSRI exposure and aggressive behavior: response to commentary by Rubin and Walkup (2012). ( Melloni, RH; Ricci, LA, 2013) |
| " The new study by Ricci and Melloni presented in the current issue of this journal shows that exposure to low-dose fluoxetine during adolescence predisposes Syrian hamsters to offensive aggression, with demonstrable neurophysiologic changes." | 3.78 | SSRIs, adolescents, and aggression: tempering human implications regarding SSRI-induced aggression in hamsters: comment on Ricci and Melloni (2012). ( Rubin, DH; Walkup, JT, 2012) |
| "Fluoxetine is the only selective serotonin reuptake inhibitor registered for the treatment of major depressive disorder in pediatric populations, despite reports that it is disproportionately associated with an array of adverse side effects that include agitation, hostility, and overt acts of pathological aggression and violence in youth." | 3.78 | Repeated fluoxetine administration during adolescence stimulates aggressive behavior and alters serotonin and vasopressin neural development in hamsters. ( Melloni, RH; Ricci, LA, 2012) |
| "Studies using dopaminergic and serotonergic agonists or antagonists implicate involvement of these systems in various aspects of early maternal behavior and postpartum aggression towards an intruder in rats, both of which are associated with the presence of oxytocin in specific brain regions." | 3.73 | The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat. ( Elliott, DL; Greenhill, KW; Hofler, VE; Johns, JM; Joyner, PW; Knupp, K; Lomas, LM; McMurray, MS; Middleton, CL; Walker, CH, 2005) |
| "These experiments aimed to investigate the effects of the cannabinoid CB1 receptor antagonist rimonabant (SR141716) in animal models measuring aspects of emotional reactivity and depression." | 3.73 | Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents. ( Griebel, G; Scatton, B; Stemmelin, J, 2005) |
| "Social isolation (SI) of male mice lasting >4 weeks is associated with aggression toward intruders and a down-regulation of brain allopregnanolone (Allo) content." | 3.72 | In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine. ( Costa, E; Dong, E; Guidotti, A; Matsumoto, K; Pinna, G, 2003) |
| "Malnutrition effect during the suckling period on aggressive behavior was investigated in adult rats treated and not treated with fluoxetine, a selective serotonin reuptake inhibitor." | 3.72 | Malnutrition during brain growth spurt alters the effect of fluoxetine on aggressive behavior in adult rats. ( Barreto-Medeiros, JM; Cabral-Filho, JE; De-Castro, CM; Feitoza, EG; Magalhaes, K; Manhaes-De-Castro, FM; Manhaes-De-Castro, R, 2004) |
| "Two individuals from a large HD pedigree with a very high prevalence of obsessive-compulsive disorder (OCD) have been treated with fluoxetine, an SSRI." | 3.71 | Fluoxetine in the treatment of Huntington's disease. ( Daniele, F; De Marchi, N; Ragone, MA, 2001) |
| "Alterations in arginine vasopressin regulation and secretion have been proposed as one possible biochemical abnormality in patients with obsessive-compulsive disorder." | 3.71 | Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder. ( Ferris, CF; Koppel, G; Messenger, T; Rasmussen, MF, 2001) |
| "Studies in several species of rodents show that arginine vasopressin (AVP) acting through a V1A receptor facilitates offensive aggression, i." | 3.69 | Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters. ( Delville, Y; Ferris, CF; Fuller, RW; Koppel, G; Melloni, RH; Perry, KW, 1997) |
| "In previous studies tryptophan and 5-hydroxy-tryptophan (5-HTP) treatments produced opposite effects on aggression and vigilance and differing effects on eating and locomoting in vervet monkeys." | 3.67 | Differential behavioral effects of tryptophan and 5-hydroxytryptophan in vervet monkeys: influence of catecholaminergic systems. ( Raleigh, MJ, 1987) |
| "Although selective serotonin reuptake inhibitors (SSRI) are generally effective in reducing impulsive aggression in individuals with intermittent explosive disorder, a large proportion of intermittent explosive disorder patients fail to achieve full remission despite adequate dosage and duration of treatment." | 2.76 | Personality predictors of antiaggressive response to fluoxetine: inverse association with neuroticism and harm avoidance. ( Coccaro, EF; Lee, R; Phan, KL, 2011) |
| " Divalproex sodium was increased as tolerated using a flexible dosing schedule." | 2.69 | Divalproex sodium for impulsive aggressive behavior in patients with personality disorder. ( Coccaro, EF; Kavoussi, RJ, 1998) |
| "Patients with unipolar depression and anger attacks frequently experience significant anxiety and somatic symptoms, and are relatively more likely to meet criteria for avoidant, dependent, borderline, narcissistic, and antisocial personality disorders than depressed patients without these attacks." | 2.40 | Depression with anger attacks. ( Fava, M, 1998) |
| " Chronic administration of fluoxetine enhanced the exploratory activity in the elevated plus-maze test and decreased the STEP46 protein level in aggressive rats' hippocampus, whereas chronic TC-2153 administration did not affect these parameters." | 1.72 | On an association between fear-induced aggression and striatal-enriched protein tyrosine phosphatase (STEP) in the brain of Norway rats. ( Bazovkina, DV; Khomenko, TM; Kozhemyakina, RV; Kulikov, AV; Kulikova, E; Moskaliuk, VS; Naumenko, VS; Salakhutdinov, NF; Terenina, E; Volcho, KP, 2022) |
| "Fluoxetine (FLX) is a selective serotonin (5-HT) reuptake inhibitor known for its effects modifying aggressiveness, personality traits, and anxiety-like behaviors." | 1.46 | Acute fluoxetine treatment increases aggressiveness in juvenile matrinxã (Brycon amazonicus). ( Barbosa Júnior, A; Serra, M; Urbinati, EC; Wolkers, CPB, 2017) |
| " This study stresses the potential fitness consequences of fluoxetine exposure and suggests that examining behavioral effects of PPCPs under different dosing regimens and in multiple contexts is important to gain an increased understanding of how exposure affects behavior." | 1.43 | Dose-dependent fluoxetine effects on boldness in male Siamese fighting fish. ( Campbell, BA; Dzieweczynski, TL; Kane, JL, 2016) |
| " In conclusion, the results show that fluoxetine exposure alters behavior beyond the level of overall response and highlights the importance of studying the behavioral effects of inadvertent pharmaceutical exposure in multiple contexts and with different dosing regimes." | 1.43 | Fluoxetine exposure impacts boldness in female Siamese fighting fish, Betta splendens. ( Campbell, BA; Dzieweczynski, TL; Kane, JL; Lavin, LE, 2016) |
| "Fluoxetine treatment significantly reduced advertisement calling and territorial behavior in E." | 1.40 | Chronic fluoxetine treatment promotes submissive behavior in the territorial frog, Eleutherodactylus coqui. ( Regen, EM; Ten Eyck, GR, 2014) |
| "Autism and catatonia have been previously reported together." | 1.36 | Onset of catatonia at puberty: electroconvulsive therapy response in two autistic adolescents. ( Barbosa, V; Ghaziuddin, M; Ghaziuddin, N; Gih, D; Maixner, DF, 2010) |
| "Fluoxetine is a selective serotonin reuptake inhibitor of the neuronal reuptake pump increasing synaptic concentrations of serotonin, and 8-OH-DPAT is a specific serotonin (5-HT1A) receptor agonist." | 1.32 | Effects of acute treatment with 8-OH-DPAT and fluoxetine on aggressive behaviour in male song sparrows (Melospiza melodia morphna). ( Sperry, TS; Thompson, CK; Wingfield, JC, 2003) |
| "Fluoxetine-treated subjects (n = 6) had significantly lower Impulsivity Index scores than controls (n = 12)." | 1.31 | Social impulsivity inversely associated with CSF 5-HIAA and fluoxetine exposure in vervet monkeys. ( Fairbanks, LA; Jorgensen, MJ; Kaplan, JR; McGuire, MT; Melega, WP, 2001) |
| "Tianeptine (TIA) is an antidepressant drug which enhances the reuptake of serotonin but, in contrast to tricyclics, shows no affinity for neurotransmitter receptors." | 1.31 | Effect of repeated treatment with tianeptine and fluoxetine on the central alpha(1)-adrenergic system. ( Dlaboga, D; Dziedzicka-Wasylewska, M; Maj, J; Rogóz, Z; Skuza, G, 2001) |
| "Fluoxetine-treated animals displayed a longer latency to exhibit parental responsiveness than did saline-treated controls (p < 0." | 1.30 | Effects of the selective serotonin reuptake inhibitor fluoxetine on social behaviors in male and female prairie voles (Microtus ochrogaster). ( Boyle, PA; Caliguri, EJ; De Vries, GJ; Villalba, C, 1997) |
| " The dose-response curve was biphasic for citalopram with a maximum of 64% inhibition." | 1.30 | Behavioral profiles of SSRIs in animal models of depression, anxiety and aggression. Are they all alike? ( Meier, E; Sánchez, C, 1997) |
| "Fluoxetine-treated patients reported an increased frequency of weight gain and anger or aggression." | 1.29 | Postmarketing surveillance by patient self-monitoring: preliminary data for sertraline versus fluoxetine. ( Bryant, SG; Fisher, S; Kent, TA, 1995) |
| "Fluoxetine is a selective inhibitor of serotonin uptake in vitro." | 1.27 | The pharmacologic profile of fluoxetine. ( Fuller, RW; Stark, P; Wong, DT, 1985) |
| " An analogous potentiation of clonidine-induced aggressiveness was obtained with chronic administration (the schedule as above) of levomepromazine (2 mg/kg) or thioridazine (5 mg/kg) but not of spiperone (0." | 1.26 | Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. ( Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (7.04) | 18.7374 |
| 1990's | 41 (28.87) | 18.2507 |
| 2000's | 38 (26.76) | 29.6817 |
| 2010's | 49 (34.51) | 24.3611 |
| 2020's | 4 (2.82) | 2.80 |
| Authors | Studies |
|---|---|
| Greene, SM | 1 |
| Szalda-Petree, AD | 1 |
| Moskaliuk, VS | 1 |
| Kozhemyakina, RV | 1 |
| Bazovkina, DV | 1 |
| Terenina, E | 1 |
| Khomenko, TM | 1 |
| Volcho, KP | 1 |
| Salakhutdinov, NF | 1 |
| Kulikov, AV | 1 |
| Naumenko, VS | 1 |
| Kulikova, E | 1 |
| Rosell, DR | 1 |
| Slifstein, M | 1 |
| Thompson, J | 1 |
| Xu, X | 1 |
| Perez-Rodriguez, MM | 1 |
| McClure, MM | 1 |
| Hazlett, EA | 2 |
| New, AS | 2 |
| Nabulsi, N | 1 |
| Huang, Y | 1 |
| Carson, RE | 1 |
| Siever, LS | 1 |
| Abi-Dargham, A | 1 |
| Koenigsberg, HW | 2 |
| Amaral, JMX | 1 |
| Padilha, MC | 1 |
| Chagas, SV | 1 |
| Baker, JS | 1 |
| Mullen, C | 1 |
| Vieira Neto, L | 1 |
| Aquino Neto, FR | 1 |
| Cruz, MS | 1 |
| Mikics, É | 1 |
| Guirado, R | 1 |
| Umemori, J | 1 |
| Tóth, M | 1 |
| Biró, L | 1 |
| Miskolczi, C | 1 |
| Balázsfi, D | 1 |
| Zelena, D | 1 |
| Castrén, E | 1 |
| Haller, J | 2 |
| Karpova, NN | 1 |
| Olds, JE | 1 |
| Barbosa, HP | 1 |
| Lima-Maximino, MG | 1 |
| Maximino, C | 1 |
| Calder, CD | 1 |
| Borns-Weil, S | 1 |
| Day, C | 1 |
| Higginbottom, KB | 1 |
| Stepita, ME | 1 |
| Bain, MJ | 1 |
| Moesta, A | 1 |
| Pineda, S | 1 |
| Anzola, B | 1 |
| Olivares, A | 1 |
| Ibáñez, M | 1 |
| Godar, SC | 1 |
| Bortolato, M | 1 |
| Castelli, MP | 1 |
| Casti, A | 1 |
| Casu, A | 1 |
| Chen, K | 1 |
| Ennas, MG | 1 |
| Tambaro, S | 1 |
| Shih, JC | 1 |
| Ten Eyck, GR | 1 |
| Regen, EM | 1 |
| Bennett, SL | 1 |
| Kiryanova, V | 2 |
| Dyck, RH | 2 |
| Forsatkar, MN | 2 |
| Nematollahi, MA | 2 |
| Amiri, BM | 1 |
| Huang, WB | 1 |
| Yang, CR | 1 |
| Bai, YY | 1 |
| Ruan, CS | 1 |
| Zhou, HF | 1 |
| Liu, D | 1 |
| Wang, XF | 1 |
| Shen, LJ | 1 |
| Zheng, HY | 1 |
| Zhou, XF | 1 |
| Denenberg, S | 1 |
| Coccaro, EF | 7 |
| Lee, R | 3 |
| Breen, EC | 1 |
| Irwin, MR | 1 |
| Svirsky, N | 1 |
| Levy, S | 1 |
| Avitsur, R | 1 |
| Giacomini, ACVV | 1 |
| Abreu, MS | 1 |
| Giacomini, LV | 1 |
| Siebel, AM | 1 |
| Zimerman, FF | 1 |
| Rambo, CL | 1 |
| Mocelin, R | 1 |
| Bonan, CD | 1 |
| Piato, AL | 1 |
| Barcellos, LJG | 1 |
| Sebire, M | 1 |
| Elphinstone Davis, J | 1 |
| Hatfield, R | 1 |
| Winberg, S | 1 |
| Katsiadaki, I | 1 |
| Dzieweczynski, TL | 3 |
| Kane, JL | 2 |
| Campbell, BA | 2 |
| Lavin, LE | 1 |
| Eisenreich, BR | 2 |
| Szalda-Petree, A | 2 |
| Martin, KM | 1 |
| Hamilton, TJ | 1 |
| Kwan, GT | 1 |
| Gallup, J | 1 |
| Tresguerres, M | 1 |
| Meunier, SJ | 1 |
| Vecchiarelli, HA | 1 |
| Hill, MN | 1 |
| Stelow, L | 1 |
| Terranova, JI | 1 |
| Song, Z | 1 |
| Larkin, TE | 1 |
| Hardcastle, N | 1 |
| Norvelle, A | 1 |
| Riaz, A | 1 |
| Albers, HE | 1 |
| Wolkers, CPB | 1 |
| Serra, M | 1 |
| Barbosa Júnior, A | 1 |
| Urbinati, EC | 1 |
| Mamiya, PC | 1 |
| Matray-Devoti, J | 1 |
| Fisher, H | 2 |
| Wagner, GC | 2 |
| HedayatiRad, M | 1 |
| Brown, C | 1 |
| McCallum, ES | 1 |
| Bose, APH | 1 |
| Warriner, TR | 1 |
| Balshine, S | 1 |
| Greene, S | 1 |
| Kavoussi, RJ | 4 |
| Ferris, CF | 4 |
| Stolberg, T | 1 |
| Kulkarni, P | 1 |
| Murugavel, M | 1 |
| Blanchard, R | 1 |
| Blanchard, DC | 1 |
| Febo, M | 1 |
| Brevard, M | 1 |
| Simon, NG | 1 |
| Mutlu, O | 1 |
| Ulak, G | 1 |
| Laugeray, A | 1 |
| Belzung, C | 2 |
| Carrillo, M | 1 |
| Ricci, LA | 3 |
| Coppersmith, GA | 1 |
| Melloni, RH | 6 |
| Koike, H | 1 |
| Ibi, D | 1 |
| Mizoguchi, H | 1 |
| Nagai, T | 1 |
| Nitta, A | 1 |
| Takuma, K | 1 |
| Nabeshima, T | 1 |
| Yoneda, Y | 1 |
| Yamada, K | 1 |
| Cervantes, MC | 1 |
| Delville, Y | 3 |
| Silva, H | 1 |
| Iturra, P | 1 |
| Solari, A | 1 |
| Villarroel, J | 1 |
| Jerez, S | 1 |
| Jiménez, M | 1 |
| Galleguillos, F | 1 |
| Bustamante, ML | 1 |
| Dingman, S | 1 |
| Hurlburt, L | 1 |
| Otte, M | 1 |
| Frye, CA | 1 |
| Rhodes, ME | 1 |
| Ghaziuddin, N | 1 |
| Gih, D | 1 |
| Barbosa, V | 1 |
| Maixner, DF | 1 |
| Ghaziuddin, M | 1 |
| George, DT | 1 |
| Phillips, MJ | 1 |
| Lifshitz, M | 1 |
| Lionetti, TA | 1 |
| Spero, DE | 1 |
| Ghassemzedeh, N | 1 |
| Doty, L | 1 |
| Umhau, JC | 1 |
| Rawlings, RR | 1 |
| McDonald, MD | 1 |
| Gonzalez, A | 1 |
| Sloman, KA | 1 |
| Nelson, M | 3 |
| Pinna, G | 5 |
| Rosado, B | 1 |
| García-Belenguer, S | 1 |
| León, M | 1 |
| Chacón, G | 1 |
| Villegas, A | 1 |
| Palacio, J | 1 |
| Phan, KL | 1 |
| Kohlert, JG | 1 |
| Mangan, BP | 1 |
| Kodra, C | 1 |
| Drako, L | 1 |
| Long, E | 1 |
| Simpson, H | 1 |
| Breuillaud, L | 1 |
| Rossetti, C | 1 |
| Meylan, EM | 1 |
| Mérinat, C | 1 |
| Halfon, O | 1 |
| Magistretti, PJ | 1 |
| Cardinaux, JR | 1 |
| Hebert, OL | 1 |
| Rubin, DH | 1 |
| Walkup, JT | 1 |
| Barry, MJ | 1 |
| Dournes, C | 1 |
| Beeské, S | 1 |
| Griebel, G | 3 |
| DeLeon, KR | 1 |
| Grimes, JM | 2 |
| Connor, DF | 2 |
| Sperry, TS | 3 |
| Thompson, CK | 1 |
| Wingfield, JC | 2 |
| Dong, E | 1 |
| Matsumoto, K | 1 |
| Costa, E | 3 |
| Guidotti, A | 3 |
| Perreault, HA | 2 |
| Semsar, K | 2 |
| Godwin, J | 2 |
| Barreto-Medeiros, JM | 1 |
| Feitoza, EG | 1 |
| Magalhaes, K | 1 |
| Cabral-Filho, JE | 1 |
| Manhaes-De-Castro, FM | 1 |
| De-Castro, CM | 1 |
| Manhaes-De-Castro, R | 1 |
| Buchsbaum, MS | 1 |
| Goodman, M | 1 |
| Lo, J | 1 |
| Iskander, L | 1 |
| Newmark, R | 1 |
| Brand, J | 1 |
| O'Flynn, K | 1 |
| Siever, LJ | 1 |
| Zanarini, MC | 1 |
| Frankenburg, FR | 1 |
| Parachini, EA | 1 |
| Moore, IT | 1 |
| Meddle, SL | 1 |
| Benowitz-Fredericks, ZM | 1 |
| Stemmelin, J | 2 |
| Scatton, B | 2 |
| Zhao, CS | 1 |
| Puurunen, K | 1 |
| Schallert, T | 1 |
| Sivenius, J | 1 |
| Jolkkonen, J | 1 |
| Johns, JM | 1 |
| Joyner, PW | 1 |
| McMurray, MS | 1 |
| Elliott, DL | 1 |
| Hofler, VE | 1 |
| Middleton, CL | 1 |
| Knupp, K | 1 |
| Greenhill, KW | 1 |
| Lomas, LM | 1 |
| Walker, CH | 1 |
| Berton, O | 1 |
| McClung, CA | 1 |
| Dileone, RJ | 1 |
| Krishnan, V | 1 |
| Renthal, W | 1 |
| Russo, SJ | 1 |
| Graham, D | 1 |
| Tsankova, NM | 1 |
| Bolanos, CA | 1 |
| Rios, M | 1 |
| Monteggia, LM | 1 |
| Self, DW | 1 |
| Nestler, EJ | 1 |
| Chan, KL | 1 |
| Campayo, A | 1 |
| Moser, DJ | 1 |
| Arndt, S | 1 |
| Robinson, RG | 1 |
| Duxbury, MM | 1 |
| Pibiri, F | 2 |
| Carboni, G | 1 |
| Taravosh-Lahn, K | 1 |
| Bastida, C | 1 |
| Cohen, C | 1 |
| Terranova, JP | 1 |
| Lopez-Grancha, M | 1 |
| Pichat, P | 1 |
| Bergis, O | 1 |
| Decobert, M | 1 |
| Santucci, V | 1 |
| Françon, D | 1 |
| Alonso, R | 1 |
| Stahl, SM | 1 |
| Keane, P | 1 |
| Avenet, P | 1 |
| le Fur, G | 1 |
| Tauscher-Wisniewski, S | 1 |
| Nilsson, M | 1 |
| Caldwell, C | 1 |
| Plewes, J | 1 |
| Allen, AJ | 1 |
| Lynn, SE | 1 |
| Egar, JM | 1 |
| Walker, BG | 1 |
| Ramenofsky, M | 1 |
| Agis-Balboa, RC | 1 |
| Kostowski, W | 1 |
| Valzelli, L | 1 |
| Kozak, W | 1 |
| Bernasconi, S | 1 |
| Carlini, EA | 1 |
| Lindsey, CJ | 1 |
| Maj, J | 3 |
| Mogilnicka, E | 1 |
| Klimek, V | 1 |
| Kordecka-Magiera, A | 1 |
| Rogóz, Z | 2 |
| Skuza, G | 2 |
| Sowińska, H | 1 |
| Ayuso Gutiérrez, JL | 1 |
| Troisi, A | 2 |
| Vicario, E | 1 |
| Nuccetelli, F | 1 |
| Ciani, N | 1 |
| Pasini, A | 1 |
| Fisher, S | 1 |
| Kent, TA | 1 |
| Bryant, SG | 1 |
| Pole, N | 1 |
| Borve, T | 1 |
| Johnson, SK | 1 |
| Sánchez, C | 2 |
| Hyttel, J | 1 |
| Overall, KL | 1 |
| Chen, C | 1 |
| Rainnie, DG | 1 |
| Greene, RW | 1 |
| Tonegawa, S | 1 |
| Heiligenstein, JH | 1 |
| Beasley, CM | 1 |
| Potvin, JH | 1 |
| Bodfish, JW | 1 |
| Madison, JT | 1 |
| Taylor, G | 1 |
| Bardgett, M | 1 |
| Csernansky, J | 1 |
| Early, T | 1 |
| Scherrer, J | 1 |
| Womack, S | 1 |
| Friedman, EH | 1 |
| Fuller, RW | 4 |
| Levy, F | 1 |
| Einfeld, S | 1 |
| Looi, J | 1 |
| Steingard, RJ | 1 |
| Deckel, AW | 1 |
| Gerra, G | 1 |
| Fertonani, G | 1 |
| Zaimovic, A | 1 |
| Rota-Graziosi, I | 1 |
| Avanzini, P | 1 |
| Caccavari, R | 1 |
| Delsignore, R | 1 |
| Lucchini, A | 1 |
| Dodman, NH | 1 |
| Donnelly, R | 1 |
| Shuster, L | 1 |
| Mertens, P | 1 |
| Rand, W | 1 |
| Miczek, K | 1 |
| Meier, E | 1 |
| Koppel, G | 2 |
| Perry, KW | 1 |
| Huber, R | 1 |
| Smith, K | 1 |
| Delago, A | 1 |
| Isaksson, K | 1 |
| Kravitz, EA | 1 |
| Constantino, JN | 1 |
| Liberman, M | 1 |
| Kincaid, M | 1 |
| Hauger, RL | 1 |
| Villalba, C | 1 |
| Boyle, PA | 1 |
| Caliguri, EJ | 1 |
| De Vries, GJ | 1 |
| Matto, V | 1 |
| Skrebuhhova, T | 1 |
| Allikmets, L | 1 |
| Fava, M | 1 |
| Singh, Y | 1 |
| Jaiswal, AK | 1 |
| Singh, M | 1 |
| Bhattacharya, SK | 2 |
| Wilkinson, D | 1 |
| Shaw, SC | 1 |
| Fletcher, AP | 1 |
| Fairbanks, LA | 1 |
| Melega, WP | 1 |
| Jorgensen, MJ | 1 |
| Kaplan, JR | 1 |
| McGuire, MT | 3 |
| De Marchi, N | 1 |
| Daniele, F | 1 |
| Ragone, MA | 1 |
| Ho, HP | 1 |
| Olsson, M | 1 |
| Westberg, L | 1 |
| Melke, J | 1 |
| Eriksson, E | 1 |
| Vargas, LC | 1 |
| Schenberg, LC | 1 |
| Dlaboga, D | 1 |
| Dziedzicka-Wasylewska, M | 1 |
| Rasmussen, MF | 1 |
| Messenger, T | 1 |
| Selzer, JA | 1 |
| Alarcon, RD | 1 |
| Johnson, BR | 1 |
| Lucas, JP | 1 |
| Raleigh, MJ | 3 |
| Brammer, GL | 1 |
| Pollack, DB | 1 |
| Yuwiler, A | 1 |
| Datla, KP | 1 |
| Mitra, SK | 1 |
| Haug, M | 1 |
| Wallian, L | 1 |
| Brain, PF | 1 |
| Everett, HC | 1 |
| Astill, JL | 1 |
| Herbert, JL | 1 |
| Schut, AG | 1 |
| Molina, V | 1 |
| Ciesielski, L | 1 |
| Gobaille, S | 1 |
| Isel, F | 1 |
| Mandel, P | 1 |
| Montgomery, SA | 1 |
| Sobin, P | 1 |
| Schneider, L | 1 |
| McDermott, H | 1 |
| Valdman, AV | 1 |
| Poshivalov, VP | 1 |
| Stark, P | 1 |
| Wong, DT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Fluoxetine on Measures of Domestic Violence[NCT00011765] | Phase 2 | 104 participants (Actual) | Interventional | 2001-02-22 | Completed | ||
| A Double-Blind, Placebo-Controlled Study of Brexpiprazole in the Treatment of Borderline Personality Disorder.[NCT03418675] | Phase 2 | 80 participants (Actual) | Interventional | 2018-11-26 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A clinician-administered assessment of anxiety that will be assessed at all study visits (Visit 1-Visit 8). Changes in scores from baseline to final visit will be assessed. Higher scores (up to 56) indicate higher levels of anxiety, with 0 being no symptoms of anxiety. (NCT03418675)
Timeframe: assessed at Visits 1 to 8, change in scores from Visit 1 to Visit 8 (baseline to Week 12) is reported
| Intervention | change in score on a scale (Mean) |
|---|---|
| Placebo | -2.41 |
| Rexulti | -4.88 |
A clinician-administered assessment of depression that will be assessed at all study visits (Visits 1-8). Higher total scores indicate higher levels of depression (up to 52), while a score of 0 would indicate no depressive symptoms. (NCT03418675)
Timeframe: Assessed at Visits 1 to 8, change in scores from Visit 1 to Visit 8 (baseline to week 12) is reported
| Intervention | change in score on a scale (Mean) |
|---|---|
| Placebo | -2.09 |
| Rexulti | -3.81 |
A self-report assessment of impulsivity that will be assessed at baseline and visit 8. The BIS is composed of 30 items describing common impulsive or non-impulsive (for reverse scored items) behaviors and preferences. Items are scored on a 4-point scale: (Rarely/Never = 1, Occasionally = 2, Often = 3, Almost Always/Always = 4). These scores are summed to produce an overall impulsivity score ranging from 30 (not impulsive) to 120 (extremely impulsive). (NCT03418675)
Timeframe: Baseline (Visit 1), Week 12 (Visit 8)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Visit 1 | Visit 8 | |
| Placebo | 76.53 | 68.13 |
| Rexulti | 72.27 | 70.5 |
A self rated scale used to measure severity and change. The first 12 items of the scale are on a scale from 1-5, with 5 meaning that the item caused extreme distress, severe difficulties in relationships, and/or kept them from getting things done. The lowest rating (1) means it caused little or no problems. Items 13-15 (positive behaviors) are rated according to frequency. Completed at every visit. (NCT03418675)
Timeframe: Assessed at Visits 1 to 8, change in scores from Visit 1 to Visit 8 (baseline to week 12) is reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Visit 1 | Visit 8 | |
| Placebo | 40.90 | 29.15 |
| Rexulti | 40.54 | 23.15 |
"A self-report scale measuring suicidality. Subjects will complete the scale at all visits. Subjects are asked about suicidal thoughts. If answers are no, rater can proceed to suicidal behavior section where subject is asked about any non-suicidal self injurious behavior. If yes, subject is asked about intensity of ideations. In the event of serious threat to themselves, the subject will be escorted to the emergency room. Total score indicates severity of suicidal ideation and behavior, with lower scores representing lower levels of suicidality and higher scores representing higher levels of suicidality. A score of 0 would reflect no suicidality present, whereas a maximum score of 5 would reflect active suicidal ideation with intent to act." (NCT03418675)
Timeframe: Baseline (Visit 1), Week 12 (Visit 8)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Visit 1 | Visit 8 | |
| Placebo | 1.15 | 0.23 |
| Rexulti | 0.73 | 0.08 |
A short-structured interview that assesses comorbid psychiatric disorders according to the DSM 5 criteria. This assessment will be done during the baseline visit. (NCT03418675)
Timeframe: Baseline (Week 1)
| Intervention | Participants (Count of Participants) | ||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Major Depressive Episode (Current) | Major Depressive Episode (Past) | Manic Episode (Current) | Manic Episode (Past) | Hypomanic Episode (Current) | Bipolar I Disorder (Current) | Bipolar I Disorder (Past) | Bipolar II Disorder (Current) | Bipolar II Disorder (Past) | Panic Disorder (Current) | Panic Disorder (Lifetime) | Agoraphobia (Current) | Social Anxiety Disorder (Current) | Obsessive Compulsive Disorder (Current) | Post Traumatic Stress Disorder (Current) | Alcohol Use Disorder (Past 12 months) | Substance Use Disorder (Past 12 months) | Any Psychotic Disorder (Current) | Any Psychotic Disorder (Lifetime) | Major Depressive Disorder with Psychotic Features (Current) | Major Depressive Disorder with Psychotic Features (Past) | Anorexia Nervosa (current) | Bulimia Nervosa (Current) | Binge Eating Disorder (Current) | Generalized Anxiety Disorder (Current) | Antisocial Personality Disorder (Lifetime) | ADHD Combined Type (Current) | ADHD Inattentive Type (Current) | ADHD Hyperactive Type (Current) | Tourette's Syndrome (Lifetime) | Persistent Motor Tic Disorder (Lifetime) | Provisional Vocal Tic Disorder (Lifetime) | Provisional Tic Disorder (Lifetime) | Specific Phobia | Body Dysmorphic Disorder (Current) | |
| Placebo | 16 | 12 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 6 | 11 | 7 | 6 | 3 | 9 | 13 | 11 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 10 | 8 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 4 | 3 |
| Rexulti | 18 | 18 | 2 | 3 | 0 | 0 | 0 | 0 | 1 | 6 | 10 | 9 | 9 | 3 | 12 | 8 | 8 | 0 | 1 | 0 | 0 | 1 | 4 | 4 | 15 | 4 | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 2 |
A self-report assessment of patient perceived quality of life that will be assessed at baseline and visit 8. Higher scores indicate a higher quality of life, whereas lower scores indicate a lower quality of life. Participants are asked to rate the importance of each domain on a 3-point scale ranging from 1=not important to 3=very important, and to rate how satisfied they are with that domain on a 6-point scale, ranging from -3=very dissatisfied to +3=very satisfied. In scoring, importance ratings are multiplied by satisfaction ratings to produce weighted satisfaction scores for each of the 16 domains. Weighted satisfaction scores are summed and divided by the number of domains that were rated as important or very important to produce a raw score, which is then converted to a t-score, which provides a proxy measurement for perceived quality of life. T-scores range from very low perceived quality of life (0-36) to high perceived quality of life (58-77). (NCT03418675)
Timeframe: Baseline (Week 1), Week 12 (Visit 8)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Visit 1 | Visit 8 | |
| Placebo | 28.89 | 30.75 |
| Rexulti | 28.70 | 35.71 |
A self-report scale assessing Borderline Personality severity that will be assessed at all visits.This scale is assessing severity and change in BPD symptoms. This is a 9-item scale measuring severity of different aspects of Borderline Personality Disorder, with each item rated on a 0-4 scale, 0=no symptoms, 4=severe symptoms. Total scores range from 0-36. (NCT03418675)
Timeframe: Baseline (Visit 1), Week 1 (Visit 2), Week 2 (Visit 3), Week 4 (Visit 4), Week 6 (Visit 5), Week 8 (Visit 6), Week 10 (Visit 7), Week 12 (Visit 8)
| Intervention | score on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | Visit 4 | Visit 5 | Visit 6 | Visit 7 | Visit 8 | |
| Placebo | 18.2 | 12.8 | 10.7 | 10.7 | 9.7 | 9.6 | 8.7 | 9.3 |
| Rexulti | 17.6 | 10.9 | 7.9 | 8.0 | 7.0 | 6.6 | 6.0 | 5.8 |
Subjects will complete the SDS at all visits. The change in scores from baseline to study completion will be assessed. The scale itself assesses the level of disability from borderline personality disorder (or target disorder) with higher scores indicating a more debilitating disorder. Scores range from 0-30. (NCT03418675)
Timeframe: Baseline (Visit 1), Week 1 (Visit 2), Week 2 (Visit 3), Week 4 (Visit 4), Week 6 (Visit 5), Week 8 (Visit 6), Week 10 (Visit 7), Week 12 (Visit 8)
| Intervention | score on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | Visit 4 | Visit 5 | Visit 6 | Visit 7 | Visit 8 | |
| Placebo | 17.3 | 13.3 | 11.5 | 12.4 | 11.7 | 11.2 | 12.0 | 12.7 |
| Rexulti | 15.8 | 10.7 | 7.8 | 7.8 | 7.0 | 7.9 | 6.9 | 7.7 |
An instrument that helps evaluate a broad range of psychological problems and symptoms of Borderline Personality Disorder psychopathology. This will be assessed at baseline and visit 8.The 115 items are rated by using a 5-step Likert scale (0=not at all, 4=very strong) and provide a global picture of borderline psychopathology. Global scores of borderline psychopathology are calculated by summing 12 items and range from 0-48. Higher scores indicate more severe symptoms of Borderline Personality Disorder. (NCT03418675)
Timeframe: Baseline, Visit 8 (Week 12)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Visit 1 | Visit 8 | |
| Placebo | 26.17 | 20.25 |
| Rexulti | 25.42 | 14.21 |
A clinician-administered scale assessing Borderline Personality Scale severity at all study visits. Scores range from 0-36. Higher scores represent worse Borderline Personality Disorder severity, and lower scores represent milder Borderline Personality Disorder severity. (NCT03418675)
Timeframe: Baseline (Visit 1), Week 1 (Visit 2), Week 2 (Visit 3), Week 4 (Visit 4), Week 6 (Visit 5), Week 8 (Visit 6), Week 10 (Visit 7), Week 12 (Visit 8)
| Intervention | score on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | Visit 4 | Visit 5 | Visit 6 | Visit 7 | Visit 8 | |
| Placebo | 14.9 | 7.6 | 4.7 | 6 | 4.2 | 5.7 | 5 | 8.4 |
| Rexulti | 14.9 | 6.7 | 5.3 | 4.4 | 4.5 | 4.9 | 4 | 3.1 |
10 reviews available for fluoxetine and Aggression
| Article | Year |
|---|---|
The effect of increased serotonergic neurotransmission on aggression: a critical meta-analytical review of preclinical studies.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal | 2009 |
Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo.
Topics: Adolescent; Aggression; Antidepressive Agents, Second-Generation; Child; Depressive Disorder, Major; | 2007 |
Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aggression; Anabolic Agents; Androstanes; Animals; Behavior, | 2008 |
[Serotonergic function and aggressive-impulsive behavior].
Topics: Adolescent; Adult; Aggression; Animals; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Macaca mulatta | 1994 |
Fluoxetine not associated with increased aggression in controlled clinical trials.
Topics: Aggression; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Double- | 1993 |
The influence of fluoxetine on aggressive behavior.
Topics: Aggression; Animals; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin | 1996 |
A clinical approach to the pharmacotherapy of aggression in children and adolescents.
Topics: Adolescent; Aggression; Brain Injuries; Child; Child Behavior Disorders; Fluoxetine; Humans; Intelle | 1996 |
Depression with anger attacks.
Topics: Aggression; Ambulatory Care; Anger; Antidepressive Agents; Arousal; Comorbidity; Depressive Disorder | 1998 |
Aggression as an adverse drug reaction.
Topics: Aggression; Anabolic Agents; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Fluoxetine; Huma | 2000 |
Fluoxetine, suicide and aggression.
Topics: Aggression; Fluoxetine; Humans; Serotonin; Suicide | 1992 |
15 trials available for fluoxetine and Aggression
| Article | Year |
|---|---|
Inflammatory markers and chronic exposure to fluoxetine, divalproex, and placebo in intermittent explosive disorder.
Topics: Adult; Aggression; Biomarkers; C-Reactive Protein; Disruptive, Impulse Control, and Conduct Disorder | 2015 |
Placebo-controlled, randomized trial of fluoxetine in the treatment of aggression in male intimate partner abusers.
Topics: Administration, Oral; Adult; Aggression; Double-Blind Method; Fluoxetine; Humans; Impulsive Behavior | 2008 |
Fluoxetine treatment of alcoholic perpetrators of domestic violence: a 12-week, double-blind, randomized, placebo-controlled intervention study.
Topics: Aggression; Alcoholics Anonymous; Alcoholism; Anger; Cognitive Behavioral Therapy; Combined Modality | 2011 |
Personality predictors of antiaggressive response to fluoxetine: inverse association with neuroticism and harm avoidance.
Topics: Adult; Aggression; Avoidance Learning; Fluoxetine; Harm Reduction; Humans; Male; Middle Aged; Neurot | 2011 |
Fluoxetine increases relative metabolic rate in prefrontal cortex in impulsive aggression.
Topics: Adult; Aggression; Antidepressive Agents, Second-Generation; Double-Blind Method; Female; Fluorodeox | 2004 |
A preliminary, randomized trial of fluoxetine, olanzapine, and the olanzapine-fluoxetine combination in women with borderline personality disorder.
Topics: Adolescent; Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Borderline Personality Disorde | 2004 |
Aggressive behavior in patients with stroke: association with psychopathology and results of antidepressant treatment on aggression.
Topics: Aged; Aggression; Analysis of Variance; Antidepressive Agents, Tricyclic; Depression; Double-Blind M | 2006 |
Effects of fluoxetine on aggressive behavior of adult inpatients with mental retardation and epilepsy.
Topics: Adult; Aggression; Epilepsy; Female; Fluoxetine; Humans; Individuality; Intellectual Disability; Mal | 1995 |
Diagnosis and fluoxetine treatment of compulsive behavior disorder of adults with mental retardation.
Topics: Adult; Aggression; Female; Fluoxetine; Humans; Intellectual Disability; Male; Obsessive-Compulsive D | 1993 |
Hostility in heroin abusers subtypes: fluoxetine and naltrexone treatment.
Topics: Adult; Aggression; Antidepressive Agents, Second-Generation; Fenfluramine; Fluoxetine; Heroin Depend | 1995 |
Use of fluoxetine to treat dominance aggression in dogs.
Topics: Aggression; Animals; Behavior, Animal; Dogs; Female; Fluoxetine; Male; Selective Serotonin Reuptake | 1996 |
Effects of serotonin reuptake inhibitors on aggressive behavior in psychiatrically hospitalized adolescents: results of an open trial.
Topics: 1-Naphthylamine; Adolescent; Aggression; Female; Fluoxetine; Humans; Inpatients; Male; Paroxetine; S | 1997 |
Serotonin function and antiaggressive response to fluoxetine: a pilot study.
Topics: Adolescent; Adolescent Behavior; Adult; Aggression; Double-Blind Method; Fenfluramine; Fluoxetine; H | 1997 |
Fluoxetine and impulsive aggressive behavior in personality-disordered subjects.
Topics: Adult; Aggression; Double-Blind Method; Fluoxetine; Humans; Impulsive Behavior; Male; Patient Dropou | 1997 |
Divalproex sodium for impulsive aggressive behavior in patients with personality disorder.
Topics: Adult; Aggression; Anticonvulsants; Antimanic Agents; Female; Fluoxetine; Humans; Impulsive Behavior | 1998 |
117 other studies available for fluoxetine and Aggression
| Article | Year |
|---|---|
Fins of Fury or Fainéant: Fluoxetine impacts the aggressive behavior of fighting fish (Betta splendens).
Topics: Aggression; Animals; Courtship; Female; Fishes; Fluoxetine; Male; Selective Serotonin Reuptake Inhib | 2022 |
On an association between fear-induced aggression and striatal-enriched protein tyrosine phosphatase (STEP) in the brain of Norway rats.
Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzothiepins; Brain; Fear; Fluoxetine; | 2022 |
Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine.
Topics: Aggression; Fluoxetine; Humans; Personality; Personality Disorders; Positron-Emission Tomography; Se | 2023 |
Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids.
Topics: Adult; Aggression; Antidepressive Agents, Second-Generation; Anxiety; Depression; Fluoxetine; Humans | 2021 |
Social Learning Requires Plasticity Enhanced by Fluoxetine Through Prefrontal Bdnf-TrkB Signaling to Limit Aggression Induced by Post-Weaning Social Isolation.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Epigenesis, Gene | 2018 |
USE OF ORAL FLUOXETINE FOR THE TREATMENT OF ABNORMAL AGGRESSION IN TWO RED-NECKED WALLABIES (MACROPUS RUFOGRISEUS).
Topics: Aggression; Animals; Animals, Zoo; Behavior, Animal; Fluoxetine; Macropodidae; Male; Selective Serot | 2017 |
Acute fluoxetine differently affects aggressive display in zebrafish phenotypes.
Topics: Aggression; Animals; Behavior, Animal; Fluoxetine; Phenotype; Selective Serotonin Reuptake Inhibitor | 2019 |
Animal Behavior Case of the Month.
Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior Therapy; Behavior, Animal; Dogs; Environment; Fea | 2019 |
Animal Behavior Case of the Month.
Topics: Aggression; Animals; Behavior Therapy; Behavior, Animal; Buspirone; Clonidine; Dogs; Female; Fluoxet | 2019 |
Animal behavior case of the month. Underlying anxiety disorder in an aggressive dog.
Topics: Aggression; Animals; Anxiety Disorders; Behavior, Animal; Dog Diseases; Dogs; Fluoxetine; Male; Sele | 2013 |
Animal behavior case of the month. Noise phobia, cognitive dysfunction, separation anxiety, attention-seeking behavior, and medical causes.
Topics: Aggression; Alprazolam; Animals; Behavior, Animal; Dog Diseases; Dogs; Dose-Response Relationship, D | 2013 |
Animal behavior case of the month. Petting intolerance.
Topics: Aggression; Animals; Behavior, Animal; Bites and Stings; Cats; Fluoxetine; Male; Play and Playthings | 2014 |
Fluoxetine combined with clorazepate dipotassium and behaviour modification for treatment of anxiety-related disorders in dogs.
Topics: Aggression; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety Disorder | 2014 |
The aggression and behavioral abnormalities associated with monoamine oxidase A deficiency are rescued by acute inhibition of serotonin reuptake.
Topics: Aggression; Animals; Behavior, Animal; Brain; Fluoxetine; Grooming; Male; Mice, 129 Strain; Mice, Kn | 2014 |
Chronic fluoxetine treatment promotes submissive behavior in the territorial frog, Eleutherodactylus coqui.
Topics: Aggression; Animal Communication; Animals; Anura; Behavior, Animal; Fluoxetine; Male; Selective Sero | 2014 |
Animal behavior case of the month. Territorial aggression.
Topics: Aggression; Animals; Behavior, Animal; Cats; Female; Fluoxetine; Selective Serotonin Reuptake Inhibi | 2014 |
Increased aggression, improved spatial memory, and reduced anxiety-like behaviour in adult male mice exposed to fluoxetine early in life.
Topics: Aggression; Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Fear; Female; Fluoxetine; M | 2014 |
Fluoxetine inhibits aggressive behaviour during parental care in male fighting fish (Betta splendens, Regan).
Topics: Aggression; Animals; Fluoxetine; Male; Perciformes; Sexual Behavior, Animal; Territoriality | 2014 |
Enhanced aggressive behaviour in a mouse model of depression.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Clozapine; Depressive Disorder; Disea | 2015 |
Animal behavior case of the month. Petting intolerance.
Topics: Aggression; Animals; Behavior, Animal; Bites and Stings; Cats; Fluoxetine; Humans; Male; Play and Pl | 2015 |
Prenatal exposure to selective serotonin reuptake inhibitors (SSRI) increases aggression and modulates maternal behavior in offspring mice.
Topics: Aggression; Animals; Behavior, Animal; Female; Fluoxetine; Male; Maternal Behavior; Mice; Pregnancy; | 2016 |
Fluoxetine and diazepam acutely modulate stress induced-behavior.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Disease Models, Animal; Female; Fluoxetine; GABA Mo | 2016 |
Prozac affects stickleback nest quality without altering androgen, spiggin or aggression levels during a 21-day breeding test.
Topics: Aggression; Animals; Behavior, Animal; Breeding; Fish Proteins; Fluoxetine; Hydrocortisone; Male; Re | 2015 |
Fluoxetine exposure impacts boldness in female Siamese fighting fish, Betta splendens.
Topics: Aggression; Animals; Dose-Response Relationship, Drug; Female; Fluoxetine; Perciformes; Selective Se | 2016 |
Behavioral effects of fluoxetine on aggression and associative learning in Siamese fighting fish (Betta splendens).
Topics: Aggression; Animals; Conditioning, Classical; Fluoxetine; Learning; Male; Perciformes; Serotonin | 2015 |
Animal Behavior Case of the Month. Reactional urine marking.
Topics: Aggression; Animals; Anti-Anxiety Agents; Cats; Eliminative Behavior, Animal; Female; Fluoxetine; Lo | 2015 |
Acute fluoxetine exposure alters crab anxiety-like behaviour, but not aggressiveness.
Topics: Aggression; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brachyura; Disease Models, An | 2016 |
Effects of maternal stress and perinatal fluoxetine exposure on behavioral outcomes of adult male offspring.
Topics: Aggression; Animals; Behavior, Animal; Brain; Disease Models, Animal; Female; Fluoxetine; Male; Mate | 2016 |
Dose-dependent fluoxetine effects on boldness in male Siamese fighting fish.
Topics: Aggression; Animals; Behavior, Animal; Competitive Behavior; Fluoxetine; Male; Perciformes; Selectiv | 2016 |
Animal Behavior Case of the Month.
Topics: Adaptation, Psychological; Aggression; Animal Husbandry; Animals; Behavior Therapy; Behavior, Animal | 2016 |
Serotonin and arginine-vasopressin mediate sex differences in the regulation of dominance and aggression by the social brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Arginine Vasopressin; Behavior, Animal; | 2016 |
Acute fluoxetine treatment increases aggressiveness in juvenile matrinxã (Brycon amazonicus).
Topics: Aggression; Aging; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Characiforme | 2017 |
Mice increased target biting behaviors 24h after co-administration of alcohol and fluoxetine.
Topics: Aggression; Alcohol Drinking; Animals; Behavior, Animal; Brain; Ethanol; Fluoxetine; Frontal Lobe; H | 2017 |
Prozac impacts lateralization of aggression in male Siamese fighting fish.
Topics: Aggression; Animals; Behavior, Animal; Fluoxetine; Functional Laterality; Gills; Male; Perciformes; | 2017 |
An evaluation of behavioural endpoints: The pharmaceutical pollutant fluoxetine decreases aggression across multiple contexts in round goby (Neogobius melanostomus).
Topics: Aggression; Animals; Behavior, Animal; Ecotoxicology; Fluoxetine; Models, Theoretical; Perciformes; | 2017 |
Of fish and mirrors: Fluoxetine disrupts aggression and learning for social rewards.
Topics: Aggression; Animals; Association Learning; Decision Making; Fishes; Fluoxetine; Male; Reaction Time; | 2017 |
Imaging the neural circuitry and chemical control of aggressive motivation.
Topics: Administration, Oral; Aggression; Amygdala; Animals; Antidiuretic Hormone Receptor Antagonists; Brai | 2008 |
Effects of neuronal and inducible NOS inhibitor 1-[2-(trifluoromethyl) phenyl] imidazole (TRIM) in unpredictable chronic mild stress procedure in mice.
Topics: Aggression; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depressive Disorder; Enzyme Inh | 2009 |
Behavioral abnormality and pharmacologic response in social isolation-reared mice.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety; Behavi | 2009 |
Serotonin 5-HT1A and 5-HT3 receptors in an impulsive-aggressive phenotype.
Topics: Aggression; Analysis of Variance; Animals; Brain; Conditioning, Psychological; Cricetinae; Fluoxetin | 2009 |
Fluoxetine: new indication. Depression in children: too many uncertainties.
Topics: Adolescent; Aggression; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepress | 2008 |
Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder.
Topics: Adolescent; Adult; Aged; Aggression; Alleles; Female; Fluoxetine; Genotype; Humans; Impulsive Behavi | 2010 |
Exploring new compounds for functional imaging using a crayfish (Procambarus clarkia) aggression paradigm.
Topics: Aggression; Animals; Astacoidea; Behavior, Animal; Dominance-Subordination; Fluorine; Fluoxetine; Ha | 2009 |
Fluoxetine-induced decrements in sexual responses of female rats and hamsters are reversed by 3α,5α-THP.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Brain Mapping; Cricetinae; Female; Fl | 2010 |
Onset of catatonia at puberty: electroconvulsive therapy response in two autistic adolescents.
Topics: Adolescent; Age of Onset; Aggression; Antidepressive Agents, Second-Generation; Antipsychotic Agents | 2010 |
Higher levels of aggression are observed in socially dominant toadfish treated with the selective serotonin reuptake inhibitor, fluoxetine.
Topics: Aggression; Animals; Batrachoidiformes; Behavior, Animal; Fluoxetine; Receptor, Serotonin, 5-HT1A; S | 2011 |
S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Corpus Striatum; Fluoxetine; Locomotion; Male; Mice | 2011 |
Effect of fluoxetine on blood concentrations of serotonin, cortisol and dehydroepiandrosterone in canine aggression.
Topics: Aggression; Animals; Behavior, Animal; Dehydroepiandrosterone; Dogs; Female; Fluoxetine; Hydrocortis | 2011 |
Decreased aggressive and locomotor behaviors in Betta splendens after exposure to fluoxetine.
Topics: Aggression; Analysis of Variance; Animals; Behavior, Animal; Fishes; Fluoxetine; Follow-Up Studies; | 2012 |
Deletion of CREB-regulated transcription coactivator 1 induces pathological aggression, depression-related behaviors, and neuroplasticity genes dysregulation in mice.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Arabidopsis Proteins; Biogenic Monoam | 2012 |
Fluoxetine alters behavioral consistency of aggression and courtship in male Siamese fighting fish, Betta splendens.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Courtship; Female; Fishes; Fluoxetine | 2012 |
Repeated fluoxetine administration during adolescence stimulates aggressive behavior and alters serotonin and vasopressin neural development in hamsters.
Topics: Aggression; Animals; Behavior, Animal; Brain; Cricetinae; Fluoxetine; Neurons; Selective Serotonin R | 2012 |
SSRIs, adolescents, and aggression: tempering human implications regarding SSRI-induced aggression in hamsters: comment on Ricci and Melloni (2012).
Topics: Aggression; Animals; Fluoxetine; Neurons; Selective Serotonin Reuptake Inhibitors; Serotonin; Vasopr | 2012 |
Effects of fluoxetine on the swimming and behavioural responses of the Arabian killifish.
Topics: Aggression; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Escape Reaction; Fluoxetine | 2013 |
Deep brain stimulation in treatment-resistant depression in mice: comparison with the CRF1 antagonist, SSR125543.
Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Brain; Deep Brain Stimulation; Depress | 2013 |
Preclinical investigations into the relationship between adolescent SSRI exposure and aggressive behavior: response to commentary by Rubin and Walkup (2012).
Topics: Aggression; Animals; Fluoxetine; Neurons; Selective Serotonin Reuptake Inhibitors; Serotonin; Vasopr | 2013 |
Adolescent cocaine exposure and offensive aggression: involvement of serotonin neural signaling and innervation in male Syrian hamsters.
Topics: Aggression; Animals; Cocaine; Cricetinae; Fluoxetine; Image Processing, Computer-Assisted; Immunohis | 2002 |
Serotonin modulates offensive attack in adolescent anabolic steroid-treated hamsters.
Topics: Aggression; Anabolic Agents; Animals; Brain Chemistry; Cricetinae; Fluoxetine; Image Processing, Com | 2002 |
Effects of acute treatment with 8-OH-DPAT and fluoxetine on aggressive behaviour in male song sparrows (Melospiza melodia morphna).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Fluoxetine; Male; Sel | 2003 |
In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine.
Topics: Aggression; Animals; Brain; Down-Regulation; Female; Fluoxetine; Male; Mice; Pregnanolone; Selective | 2003 |
Fluoxetine treatment decreases territorial aggression in a coral reef fish.
Topics: Aggression; Animals; Fluoxetine; Male; Perciformes; Selective Serotonin Reuptake Inhibitors; Seroton | 2003 |
Malnutrition during brain growth spurt alters the effect of fluoxetine on aggressive behavior in adult rats.
Topics: Aggression; Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Brain; Fluoxetin | 2004 |
Fluoxetine-treated male wrasses exhibit low AVT expression.
Topics: Aggression; Animals; Dominance-Subordination; Fishes; Fluoxetine; Gene Expression; Male; Preoptic Ar | 2004 |
Increased sensitivity of the serotonergic system during the breeding season in free-living American tree sparrows.
Topics: Aggression; Analysis of Variance; Animals; Body Weights and Measures; Female; Fluoxetine; Male; Repr | 2005 |
Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aggression; Animals; Behavior; Brain; Estrogens; Female; Fluo | 2005 |
Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents.
Topics: Aggression; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Genera | 2005 |
Behavioral and histological effects of chronic antipsychotic and antidepressant drug treatment in aged rats with focal ischemic brain injury.
Topics: Affect; Aggression; Aging; Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; B | 2005 |
The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat.
Topics: Aggression; Animals; Behavior, Animal; Brain; Dopamine Uptake Inhibitors; Dose-Response Relationship | 2005 |
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.
Topics: Aggression; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Dominance | 2006 |
Animal behavior case of the month. A dog's aggression toward family members.
Topics: Aggression; Animals; Behavior Therapy; Behavior, Animal; Breeding; Dogs; Fear; Fluoxetine; Male; Sel | 2006 |
Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids.
Topics: Aggression; Androgens; Anesthetics; Animals; Behavior, Animal; Brain; Brain Chemistry; Dose-Response | 2006 |
Differential responsiveness to fluoxetine during puberty.
Topics: Age Factors; Aggression; Agonistic Behavior; Animals; Cricetinae; Dose-Response Relationship, Drug; | 2006 |
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aggression; Animals; Anti-Anxiety Age | 2008 |
Fish on Prozac: a simple, noninvasive physiology laboratory investigating the mechanisms of aggressive behavior in Betta splendens.
Topics: Aggression; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fishes; Fluoxetine; Humans; | 2007 |
Activity of desipramine, fluoxetine and nomifensine on spontaneous and p-CPA-induced muricidal aggression.
Topics: Aggression; Animals; Antidepressive Agents; Desipramine; Fenclonine; Fluoxetine; Humans; Male; Nomif | 1984 |
Effect of serotonergic drugs on the aggressiveness induced by delta 9-tetrahydrocannabinol in rem-sleep-deprived rats.
Topics: Aggression; Animals; Cinanserin; Cyproheptadine; Dronabinol; Drug Interactions; Fenclonine; Fluoxeti | 1982 |
Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brompheniramine; Clonidine; Drug Synergis | 1981 |
Effects of chronic treatment with antidepressants on aggressiveness induced by clonidine in mice.
Topics: Aggression; Animals; Antidepressive Agents; Citalopram; Clonidine; Drug Interactions; Fluoxetine; Fl | 1982 |
Postmarketing surveillance by patient self-monitoring: preliminary data for sertraline versus fluoxetine.
Topics: 1-Naphthylamine; Adult; Adverse Drug Reaction Reporting Systems; Aggression; Ambulatory Care; Confid | 1995 |
Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression.
Topics: Aggression; Animals; Behavior, Animal; Brain; Drug Synergism; Ethanol; Fenfluramine; Fluoxetine; Hyd | 1993 |
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors.
Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis o | 1994 |
Animal behavior case of the month. Periodic aggression toward the owner.
Topics: Aggression; Animals; Animals, Domestic; Behavior Therapy; Buspirone; Combined Modality Therapy; Dogs | 1995 |
Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II.
Topics: Aggression; Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-C | 1994 |
Male reproductive systems under chronic fluoxetine or trimipramine treatment.
Topics: Adrenal Cortex Hormones; Aggression; Animals; Antidepressive Agents, Second-Generation; Antidepressi | 1996 |
Fluoxetine and aggressive behaviour.
Topics: Adult; Aggression; Epilepsy; Fluoxetine; Humans; Intellectual Disability; Selective Serotonin Reupta | 1996 |
Combined pharmacotherapy or polypharmacy?
Topics: Aggression; Akathisia, Drug-Induced; Amitriptyline; Antidepressive Agents, Tricyclic; Attention Defi | 1996 |
Fluoxetine effects on serotonin function and aggressive behavior.
Topics: Aggression; Animals; Behavior, Animal; Fluoxetine; Humans; Rats; Serotonin | 1996 |
Serotonin diminishes aggression by suppressing the activity of the vasopressin system.
Topics: Aggression; Animals; Behavior, Animal; Cricetinae; Fluoxetine; Male; Serotonin; Time Factors; Vasopr | 1996 |
Behavioral changes in Anolis carolinensis following injection with fluoxetine.
Topics: Aggression; Animals; Depression, Chemical; Fluoxetine; Functional Laterality; Lizards; Male; Orbit; | 1996 |
Behavioral profiles of SSRIs in animal models of depression, anxiety and aggression. Are they all alike?
Topics: 1-Naphthylamine; Aggression; Animals; Anxiety; Binding, Competitive; Citalopram; Depression; Fluoxet | 1997 |
Fluoxetine and aggression.
Topics: Aggression; Animals; Behavior, Animal; Epilepsy; Fluoxetine; Humans; Intellectual Disability; Rats | 1997 |
Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters.
Topics: Aggression; Animals; Arginine Vasopressin; Behavior, Animal; Cricetinae; Fluoxetine; Hypothalamus, A | 1997 |
Serotonin and aggressive motivation in crustaceans: altering the decision to retreat.
Topics: Aggression; Animals; Astacoidea; Fluoxetine; Hemolymph; Infusions, Parenteral; Motivation; Multivari | 1997 |
Effects of the selective serotonin reuptake inhibitor fluoxetine on social behaviors in male and female prairie voles (Microtus ochrogaster).
Topics: Aggression; Animals; Arvicolinae; Brain Chemistry; Female; Fluoxetine; Male; Selective Serotonin Reu | 1997 |
The effect of antidepressants on rat aggressive behavior in the electric footshock and apomorphine-induced aggressiveness paradigms.
Topics: Aggression; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive | 1998 |
Effect of prenatal diazepam, phenobarbital, haloperidol and fluoxetine exposure on foot shock induced aggression in rats.
Topics: Aggression; Animals; Diazepam; Drug Evaluation, Preclinical; Electroshock; Female; Fluoxetine; Halop | 1998 |
Loss of anxiety and increased aggression in a 15-year-old boy taking fluoxetine.
Topics: Adolescent; Aggression; Antidepressive Agents, Second-Generation; Anxiety; Fluoxetine; Humans; Male; | 1999 |
Social impulsivity inversely associated with CSF 5-HIAA and fluoxetine exposure in vervet monkeys.
Topics: Age Factors; Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Fluoxetine; Homovanillic A | 2001 |
Fluoxetine in the treatment of Huntington's disease.
Topics: Affect; Aggression; Antidepressive Agents, Second-Generation; Cognition Disorders; Disease Progressi | 2001 |
The serotonin reuptake inhibitor fluoxetine reduces sex steroid-related aggression in female rats: an animal model of premenstrual irritability?
Topics: Aggression; Animals; Behavior, Animal; Brain; Disease Models, Animal; Estradiol; Estrus; Female; Flu | 2001 |
Long-term effects of clomipramine and fluoxetine on dorsal periaqueductal grey-evoked innate defensive behaviours of the rat.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clo | 2001 |
Effect of repeated treatment with tianeptine and fluoxetine on the central alpha(1)-adrenergic system.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aggression; Animals; Binding, Competitive; | 2001 |
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder.
Topics: Adrenergic Uptake Inhibitors; Aggression; Animals; Arginine Vasopressin; Behavior, Animal; Clomipram | 2001 |
Fluoxetine, suicidal ideation, and aggressive behavior.
Topics: Aggression; Depressive Disorder; Female; Fluoxetine; Humans; Middle Aged; Recurrence; Social Isolati | 1992 |
Paranoid and aggressive behavior in two obsessive-compulsive adolescents treated with clomipramine.
Topics: Adolescent; Aggression; Carbamazepine; Child; Clomipramine; Dose-Response Relationship, Drug; Fluoxe | 1991 |
Bidirectional relationships between tryptophan and social behavior in vervet monkeys.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Awareness; Chlorocebus aethiops; Female; Fluoxetine; Locom | 1991 |
Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys.
Topics: Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Cyproheptadine; Fenfluramine; Fluoxetin | 1991 |
Serotonergic modulation of footshock induced aggression in paired rats.
Topics: 5-Hydroxytryptophan; Aggression; Agonistic Behavior; Animals; Apomorphine; Citalopram; Clorgyline; D | 1991 |
Effects of 8-OH-DPAT and fluoxetine on activity and attack by female mice towards lactating intruders.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Brain Chemistry; Fema | 1990 |
Serotonergic activity and hostility.
Topics: Adult; Aggression; Depressive Disorder; Female; Fluoxetine; Hostility; Humans; Male; Marital Therapy | 1990 |
Fluoxetine treatment of impulsive aggression in DSM-III-R personality disorder patients.
Topics: Adult; Aggression; Antisocial Personality Disorder; Borderline Personality Disorder; Disruptive, Imp | 1990 |
Inhibition of mouse killing behavior by serotonin-mimetic drugs: effects of partial alterations of serotonin neurotransmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Citalopram; Fenclonine; Fluoxetine; Hyd | 1987 |
The benefits and risks of 5-HT uptake inhibitors in depression.
Topics: Aggression; Depressive Disorder; Female; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Male; Seroton | 1988 |
Fluoxetine in the treatment of agitated dementia.
Topics: Aggression; Dementia; Fluoxetine; Humans; Male; Middle Aged; Psychomotor Agitation | 1989 |
Differential behavioral effects of tryptophan and 5-hydroxytryptophan in vervet monkeys: influence of catecholaminergic systems.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Arousal; Behavior, Animal; Brain; Chlorocebus aethiops; De | 1987 |
Pharmaco-ethological analysis of antidepressant drug effects.
Topics: Aggression; Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Fluoxetine; Imipramine; I | 1986 |
The pharmacologic profile of fluoxetine.
Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Brain; Cats; Corticosterone; Fluoxetin | 1985 |