Page last updated: 2024-10-27

fluoxetine and African Lymphoma

fluoxetine has been researched along with African Lymphoma in 6 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
" We report that the SSRI fluoxetine and the NSRI maprotiline are potent antiproliferative agents against human Burkitt lymphoma (BL), having little effect on normal blood cells."7.76The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters. ( Cloonan, SM; Drozgowska, A; Fayne, D; Williams, DC, 2010)
" We report that the SSRI fluoxetine and the NSRI maprotiline are potent antiproliferative agents against human Burkitt lymphoma (BL), having little effect on normal blood cells."3.76The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters. ( Cloonan, SM; Drozgowska, A; Fayne, D; Williams, DC, 2010)
" Here we show that 3 structurally distinct SSRIs--fluoxetine, paroxetine, and citalopram--act directly on Burkitt lymphoma (BL) cells to trigger rapid and extensive programmed cell death."3.72Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells. ( Barnes, NM; Bunce, CM; Chamba, A; Drayson, MT; Gordon, J; Grafton, G; Gregory, CD; Holder, MJ; Luong, QT; Serafeim, A, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cloonan, SM2
Drozgowska, A1
Fayne, D1
Williams, DC2
Serafeim, A2
Holder, MJ2
Grafton, G2
Chamba, A3
Drayson, MT2
Luong, QT1
Bunce, CM2
Gregory, CD2
Barnes, NM3
Gordon, J4
Meredith, EJ1
Challa, A1
Drake-Lee, A1
Pilkington, G1
Blakely, RD2
Dyer, MJ1
Barnes, N1
Meredith, E1
Drayson, M1
Bowery, NG1

Other Studies

6 other studies available for fluoxetine and African Lymphoma

ArticleYear
The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:3

    Topics: Animals; Antidepressive Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; D

2010
The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma.
    International journal of cancer, 2011, Apr-01, Volume: 128, Issue:7

    Topics: Antidepressive Agents, Second-Generation; Apoptosis; Autophagy; bcl-2 Homologous Antagonist-Killer P

2011
Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells.
    Blood, 2003, Apr-15, Volume: 101, Issue:8

    Topics: Apoptosis; B-Lymphocytes; Burkitt Lymphoma; Calcium Signaling; Carrier Proteins; Citalopram; Fluoxet

2003
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Burkitt L

2005
In response to "Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia?" by C. Schuster, et al. [Biochem. Pharmacol. 74 (9) 2007 1424-1435].
    Biochemical pharmacology, 2008, Mar-15, Volume: 75, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Fluoxetine; Humans; Leukemia;

2008
5-Hydroxytryptamine drives apoptosis in biopsylike Burkitt lymphoma cells: reversal by selective serotonin reuptake inhibitors.
    Blood, 2002, Apr-01, Volume: 99, Issue:7

    Topics: Apoptosis; Biopsy; Blotting, Western; Burkitt Lymphoma; Carrier Proteins; Caspases; Cell Survival; C

2002