fluorouracil has been researched along with Zollinger-Ellison Syndrome in 9 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Zollinger-Ellison Syndrome: A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, HD | 1 |
| Ruffner, BW | 1 |
| Hardy, JD | 1 |
| Doolittle, PD | 1 |
| Maltz, C | 1 |
| Lightdale, CJ | 1 |
| Ruszniewski, P | 1 |
| Hochlaf, S | 1 |
| Rougier, P | 1 |
| Mignon, M | 1 |
| Mee, AS | 1 |
| Norton, JA | 2 |
| Sugarbaker, PH | 1 |
| Doppman, JL | 2 |
| Wesley, RA | 1 |
| Maton, PN | 2 |
| Gardner, JD | 2 |
| Jensen, RT | 1 |
| von Schrenck, T | 1 |
| Howard, JM | 1 |
| Smith, FP | 1 |
| Vinayek, R | 1 |
| Frucht, H | 1 |
| Wank, SA | 1 |
| Barragry, TP | 1 |
| Wick, MR | 1 |
| Delaney, JP | 1 |
1 review available for fluorouracil and Zollinger-Ellison Syndrome
| Article | Year |
|---|---|
[Zollinger-Ellison syndrome].
Topics: Benzimidazoles; Calcium; Cimetidine; Diarrhea; Duodenal Ulcer; Female; Fluorouracil; Gastrectomy; Ga | 1984 |
1 trial available for fluorouracil and Zollinger-Ellison Syndrome
| Article | Year |
|---|---|
[Intravenous chemotherapy with streptozotocin and 5 fluorouracil for hepatic metastases of Zollinger-Ellison syndrome. A prospective multicenter study in 21 patients].
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouraci | 1991 |
7 other studies available for fluorouracil and Zollinger-Ellison Syndrome
| Article | Year |
|---|---|
Chemotherapy for malignant Zollinger-Ellison tumors: successful treatment with streptozocin and fluorouracil.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Drug Therapy, Combination; Fluorouracil; Gastrins | 1976 |
Zollinger-Ellison syndrome: special considerations.
Topics: Adolescent; Adult; Aged; Child; Diarrhea; Female; Fluorouracil; Gastrectomy; Gastric Juice; Gastrins | 1977 |
The Zollinger-Ellison syndrome: a new approach.
Topics: Cimetidine; Drug Therapy, Combination; Fluorouracil; Humans; Laparoscopy; Male; Middle Aged; Radiogr | 1979 |
The Zollinger-Ellison syndrome--diagnosis and management.
Topics: Doxorubicin; Fluorouracil; Gastric Acid; Histamine H2 Antagonists; Humans; Streptozocin; Zollinger-E | 1985 |
Aggressive resection of metastatic disease in selected patients with malignant gastrinoma.
Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Combin | 1986 |
Prospective study of chemotherapy in patients with metastatic gastrinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Gast | 1988 |
Pancreatic islet cell carcinoma with gastrin and vasoactive intestinal polypeptide production.
Topics: Adenoma, Islet Cell; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Gastrins; | 1985 |