fluorouracil has been researched along with Vulvar Diseases in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Vulvar Diseases: Pathological processes of the VULVA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During the final 2 years, the protocol incorporated two different 5-fluorouracil (5-FU) regimens: routine once-weekly applications as prophylaxis against postoperative recurrence, and twice-weekly dosing to avoid further laser surgery among patients with early but diffuse failures." | 1.28 | Superficial laser vulvectomy. IV. Extended laser vaporization and adjunctive 5-fluorouracil therapy of human papillomavirus-associated vulvar disease. ( Daoud, Y; Greenberg, MD; Lörincz, AT; Pizzuti, D; Reid, R; Stoler, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mayeaux, EJ | 1 |
| Harper, MB | 1 |
| Barksdale, W | 1 |
| Pope, JB | 1 |
| Friedrich, EG | 1 |
| Emokpare, NA | 1 |
| Reid, R | 1 |
| Greenberg, MD | 1 |
| Lörincz, AT | 1 |
| Daoud, Y | 1 |
| Pizzuti, D | 1 |
| Stoler, M | 1 |
1 review available for fluorouracil and Vulvar Diseases
| Article | Year |
|---|---|
Noncervical human papillomavirus genital infections.
Topics: Condylomata Acuminata; Cryosurgery; Diagnosis, Differential; Electrocoagulation; Female; Fluorouraci | 1995 |
3 other studies available for fluorouracil and Vulvar Diseases
| Article | Year |
|---|---|
Evaluation and management of diseases of the vulva: therapeutic principles and techniques.
Topics: Abscess; Bartholin's Glands; Condylomata Acuminata; Cryosurgery; Cysts; Electrosurgery; Female; Fluo | 1978 |
Observations on a clinico-therapeutic trial with topical 5-fluor-uracil (EFUDIX) in condylomata acuminata.
Topics: Adolescent; Adult; Anus Diseases; Condylomata Acuminata; Evaluation Studies as Topic; Female; Fluoro | 1975 |
Superficial laser vulvectomy. IV. Extended laser vaporization and adjunctive 5-fluorouracil therapy of human papillomavirus-associated vulvar disease.
Topics: Cohort Studies; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Human | 1990 |