fluorouracil has been researched along with Vertigo in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levamisole was administered to 38 patients orally three times a day for 5 days concurrently with a course of 5-FU administered daily by rapid intravenous injection for 5 days." | 2.69 | Clinical and pharmacokinetic studies of high-dose levamisole in combination with 5-fluorouracil in patients with advanced cancer. ( Bagniewski, PG; Kovach, JS; Moertel, CG; O'Connell, MJ; Reid, JM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vietor, NO | 1 |
| George, BJ | 1 |
| Pulcini, C | 1 |
| Vandenbos, F | 1 |
| Bernard, E | 1 |
| Roth, S | 1 |
| Elbeze, JP | 1 |
| Dunais, B | 1 |
| Peyrade, F | 1 |
| Dellamonica, P | 1 |
| Reid, JM | 1 |
| Kovach, JS | 1 |
| O'Connell, MJ | 1 |
| Bagniewski, PG | 1 |
| Moertel, CG | 1 |
1 review available for fluorouracil and Vertigo
| Article | Year |
|---|---|
Oxaliplatin-induced hepatocellular injury and ototoxicity: a review of the literature and report of unusual side effects of a commonly used chemotherapeutic agent.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Inju | 2012 |
1 trial available for fluorouracil and Vertigo
| Article | Year |
|---|---|
Clinical and pharmacokinetic studies of high-dose levamisole in combination with 5-fluorouracil in patients with advanced cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Confusion; Drug Synergism; Drug The | 1998 |
1 other study available for fluorouracil and Vertigo
| Article | Year |
|---|---|
[Diagnosis of a metastatic valvular tumor in a living patient].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Ischemia; Car | 2003 |