fluorouracil has been researched along with Vascular Diseases in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following gastrectomy for locally advanced adenocarcinomas, three patients developed microangiopathic hemolytic anemia and renal failure shortly after completing courses of adjuvant chemotherapy with mitomycin and 5-FU." | 3.66 | Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome. ( Band, PR; Bettez, P; Giroux, L; Gruber, J; Jolivet, J; Laurin, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calderaro, J | 1 |
| Azoulay, D | 1 |
| Zafrani, ES | 1 |
| Abaci, HE | 1 |
| Shen, YI | 1 |
| Tan, S | 1 |
| Gerecht, S | 1 |
| Daher, IN | 1 |
| Yeh, ET | 1 |
| Mohan, P | 1 |
| Sukumar, R | 1 |
| Surendran, R | 1 |
| Sathyabhama, C | 1 |
| Jayanthi, V | 1 |
| Pansegrau, GK | 1 |
| Grant, DR | 1 |
| Norris, B | 1 |
| Gelmon, KA | 1 |
| Jolivet, J | 1 |
| Giroux, L | 1 |
| Laurin, S | 1 |
| Gruber, J | 1 |
| Bettez, P | 1 |
| Band, PR | 1 |
| Rothenberg, ML | 1 |
| Meropol, NJ | 1 |
| Poplin, EA | 1 |
| Van Cutsem, E | 1 |
| Wadler, S | 1 |
| Boesen, EA | 1 |
2 reviews available for fluorouracil and Vascular Diseases
| Article | Year |
|---|---|
Vascular complications of selected cancer therapies.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimet | 2008 |
Chemotherapy of bronchial carcinoma.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Blood Cell Count; Bone Marrow Diseases; Bronchial N | 1973 |
6 other studies available for fluorouracil and Vascular Diseases
| Article | Year |
|---|---|
Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Colorectal Neoplasms; Drug Therapy; Fluorouracil; | 2014 |
Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease.
Topics: Animals; Atherosclerosis; Capillary Permeability; Endothelial Cells; Endothelium, Vascular; Fluorour | 2014 |
Hepatocellular carcinoma in membranous obstruction of the inferior vena cava--a causal or a casual presentation.
Topics: Adult; Angioplasty, Balloon; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Female; Flu | 2009 |
Trastuzumab-associated peripheral vascular toxicity.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot | 2007 |
Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome.
Topics: Adenocarcinoma; Adult; Anemia, Hemolytic; Drug Therapy, Combination; Female; Fluorouracil; Humans; K | 1983 |
Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cause of Death; Fluorouracil; Gastroin | 2001 |