fluorouracil has been researched along with Uveal Neoplasms in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Uveal Neoplasms: Tumors or cancer of the UVEA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jakubechova, J | 1 |
| Smolkova, B | 1 |
| Furdova, A | 1 |
| Demkova, L | 1 |
| Altanerova, U | 1 |
| Nicodemou, A | 1 |
| Zeleznikova, T | 1 |
| Klimova, D | 1 |
| Altaner, C | 1 |
| Liu, S | 1 |
| Zhang, J | 1 |
| Fang, S | 1 |
| Su, X | 1 |
| Zhang, Q | 1 |
| Zhu, G | 1 |
| Zhu, L | 1 |
| Zhao, M | 1 |
| Liu, F | 1 |
| Péguillet, I | 1 |
| Milder, M | 1 |
| Louis, D | 1 |
| Vincent-Salomon, A | 1 |
| Dorval, T | 1 |
| Piperno-Neumann, S | 1 |
| Scholl, SM | 1 |
| Lantz, O | 1 |
| Tay, E | 1 |
| Cree, IA | 1 |
| Hungerford, J | 1 |
| Franks, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Quantifying Systemic Immunosuppression to Personalize Cancer Therapy[NCT04941365] | 0 participants (Actual) | Interventional | 2022-07-07 | Withdrawn (stopped due to please refer to NCT05621837) | |||
| Quantifying Systemic Immunosuppression to Personalize Cancer Therapy[NCT05621837] | 1,000 participants (Anticipated) | Observational | 2022-03-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for fluorouracil and Uveal Neoplasms
| Article | Year |
|---|---|
Suicide-Gene-Modified Extracellular Vesicles of Human Primary Uveal Melanoma in Future Therapies.
Topics: Animals; Extracellular Vesicles; Flucytosine; Fluorouracil; Humans; Melanoma; Skin Neoplasms; Uveal | 2023 |
Antitumor efficacy of oncolytic HSV-1 expressing cytosine deaminase is synergistically enhanced by DPD down-regulation and EMT inhibition in uveal melanoma xenograft.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Cytosine De | 2020 |
High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cancer Vaccines; CD4-Positive T-Ly | 2014 |
High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cancer Vaccines; CD4-Positive T-Ly | 2014 |
High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cancer Vaccines; CD4-Positive T-Ly | 2014 |
High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cancer Vaccines; CD4-Positive T-Ly | 2014 |
Recurrence of treated ciliary body melanoma following trabeculectomy.
Topics: Aged; Brachytherapy; Ciliary Body; Combined Modality Therapy; Conjunctival Neoplasms; Eye Enucleatio | 2009 |