fluorouracil has been researched along with Uterine Diseases in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Uterine Diseases: Pathological processes involving any part of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although anastrozole, methotrexate, and progesterone were ineffective, 5-FU significantly decreased the proliferation of endometriotic cells in vitro and controlled the growth of both cells from ovarian endometrioma and deep infiltrating endometriosis." | 7.76 | Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo. ( Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B, 2010) |
| "The ulcers were mostly singular and measured 0." | 5.28 | Chronic ulcerations following topical therapy with 5-fluorouracil for vaginal human papillomavirus-associated lesions. ( Helmkamp, BF; Krebs, HB, 1991) |
| "Although anastrozole, methotrexate, and progesterone were ineffective, 5-FU significantly decreased the proliferation of endometriotic cells in vitro and controlled the growth of both cells from ovarian endometrioma and deep infiltrating endometriosis." | 3.76 | Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo. ( Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B, 2010) |
| "The ulcers were mostly singular and measured 0." | 1.28 | Chronic ulcerations following topical therapy with 5-fluorouracil for vaginal human papillomavirus-associated lesions. ( Helmkamp, BF; Krebs, HB, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ngô, C | 1 |
| Nicco, C | 1 |
| Leconte, M | 1 |
| Chéreau, C | 1 |
| Weill, B | 1 |
| Batteux, F | 1 |
| Chapron, C | 1 |
| Krebs, HB | 1 |
| Helmkamp, BF | 1 |
2 other studies available for fluorouracil and Uterine Diseases
| Article | Year |
|---|---|
Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.
Topics: Adult; Anastrozole; Animals; Antineoplastic Agents; Biopsy; Case-Control Studies; Cell Proliferation | 2010 |
Chronic ulcerations following topical therapy with 5-fluorouracil for vaginal human papillomavirus-associated lesions.
Topics: Administration, Intravaginal; Adolescent; Adult; Aged; Cervix Uteri; Chronic Disease; Female; Fluoro | 1991 |