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fluorouracil and Urogenital Neoplasms

fluorouracil has been researched along with Urogenital Neoplasms in 17 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Urogenital Neoplasms: Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's1 (5.88)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Denck, H1
von Krogh, G1
Weismann, K1
Kassis, V1
Kosmidis, PA1
Bacoyiannis, C1
Fountzilas, G1
Aravantinos, G1
Tsavaris, N1
Milathianakis, C1
Skarlos, D1
Carter, SK1
Wasserman, TH1
Oberfield, RA1
Merrin, CE1
Murphy, GP1
Reuter, HJ1
Gary-Bobo, J1
Kühböck, J1
Furnari, S1
Pavone-Macaluso, M1
Veroux, G1
Mattea, E1
Nathanson, L1
Hall, TC1
Schilling, A1
Miller, S1
Moore, GE1
Bross, ID1
Ausmans, R1
Nadler, S1
Jones, R1
Slack, N1
Rimm, AA1
Jacobs, EM2
Reeves, WJ1
Wood, DA2
Pugh, R1
Braunwald, J1
Bateman, JR1
Israel, L1
Bernard, E1
Luce, JK1
Takayasu, H1
Aso, Y1
Hirose, K1
Okada, K1
Hoshino, Y1

Trials

5 trials available for fluorouracil and Urogenital Neoplasms

ArticleYear
Podophyllotoxin for condylomata acuminata eradication. Clinical and experimental comparative studies on Podophyllum lignans, colchicine and 5-fluorouracil.
    Acta dermato-venereologica. Supplementum, 1981, Volume: 98

    Topics: Administration, Topical; Animals; Clinical Trials as Topic; Colchicine; Condylomata Acuminata; Ethan

1981
[Treatment of condyloma acuminatum with 0.5% 5-fluorouracil-solution, A double-blind clinical trial].
    Zeitschrift fur Hautkrankheiten, 1982, Jun-01, Volume: 57, Issue:11

    Topics: Administration, Topical; Adolescent; Adult; Anus Neoplasms; Clinical Trials as Topic; Condylomata Ac

1982
5-Fluorouracil, interferon-alpha-2b and cisplatin (FAP) for advanced urothelial cancer. A phase II study. Hellenic Co-operative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans

1997
Concurrent combination chemotherapy of human solid tumors: experience with a three-drug regimen and review of the literature.
    Cancer research, 1969, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Neoplasms; Carcinoma; Child; Child, Preschool; Clinical T

1969
Effects of 5-fluorouracil (NSC-19893) in 389 patients with cancer. Eastern Clinical Drug Evaluation Program.
    Cancer chemotherapy reports, 1968, Volume: 52, Issue:6

    Topics: Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans

1968

Other Studies

12 other studies available for fluorouracil and Urogenital Neoplasms

ArticleYear
[Results of intermittent intra-arterial chemotherapy with 5-FU in liver metastases and inoperable tumors of the gastrointestinal and urogenital tracts].
    Onkologie, 1984, Volume: 7, Issue:3

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Drug Tolerance; Female; Fluorouracil; Gastroi

1984
The chemotherapy of urologic cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Co

1975
Recent trends in chemotherapy of solid tumors.
    The Medical clinics of North America, 1975, Volume: 59, Issue:2

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neopl

1975
Chemotherapy of urogenital cancer.
    Surgery annual, 1976, Volume: 8

    Topics: Adenocarcinoma; Adult; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Hum

1976
[Multifactorial immunological treatment of cancer in urology].
    Helvetica chirurgica acta, 1976, Volume: 43, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antibody Formation; Cobalt Radioisotopes; Female; Fluorouracil; Humans;

1976
[Mitomycin alone and in therapeutic association in the palliative treatment of solid tumors].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1971, Volume: 52, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Cobalt Isotopes; Cyclophosphamide; Drug Combinations; Femal

1971
[Indication and achievements of after-care examinations of urologic tumors. Chemotherapeutic report].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1973, Volume: 0, Issue:0

    Topics: Aftercare; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; H

1973
Cancer chemotherapy in urology.
    Urologia internationalis, 1971, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal

1971
Treatment of cancer with weekly intravenous 5-fluorouracil. Study by the Western Cooperative Cancer Chemotherapy Group (WCCCG).
    Cancer, 1971, Volume: 27, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Gastrointestinal D

1971
[218 cases of prolonged polychemotherapy in advanced cancer (especially bronchopulmonary). Modalities and results].
    Le Poumon et le coeur, 1968, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bronchial Neop

1968
Treatment of cancer with weekly intravenous 5-fluorouracil.
    Cancer, 1968, Volume: 22, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Injections,

1968
[Effect of 5-fluorouracil on malignant genito-urinary tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1969, Volume: 15, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Child; Female; Fluorouracil; Humans; Male; Middle Aged; Radiothe

1969