Page last updated: 2024-10-27

fluorouracil and Urethral Diseases

fluorouracil has been researched along with Urethral Diseases in 10 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Urethral Diseases: Pathological processes involving the URETHRA.

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of intraurethral 5-fluorouracil and systemic administration of interferon-alpha 2a in the therapy of condylomata acuminata or flat condylomata of the urethra is assessed."5.07Treatment of urethral condylomata acuminata or flat condylomata with interferon-alpha 2a. ( Cardamakis, E; Korantzis, A; Kotoulas, IG; Mantouvalos, H; Metalinos, K; Papathanasiou, Z; Relakis, K; Scarpari, M, 1994)
"Approximately 20% of HPV-associated genital warts occur in the urethra."1.72Successfully treated urethral condyloma acuminatum utilizing intraurethral self-application of 5-fluorouracil via Q-tip. ( Goldman, HB; Leone, G; Zillioux, J, 2022)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's2 (20.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Zillioux, J1
Leone, G1
Goldman, HB1
Ge, CG1
Jiang, J1
Jiang, Q1
Liu, C1
Hu, ZL1
Liang, PH1
Zhang, WL1
Gammon, DC1
Reed, KA1
Patel, M1
Balaji, KC1
Xiao, MZ1
Gou, X1
He, ZM1
Wen, YC1
Wu, HH1
Chen, KK1
Cardamakis, E1
Kotoulas, IG1
Metalinos, K1
Mantouvalos, H1
Relakis, K1
Scarpari, M1
Korantzis, A1
Papathanasiou, Z1
West, AF1
Leung, HY1
Powell, PH1
von Krough, G1
Dretler, SP1
Klein, LA1
Bissada, NK1
Redman, JF1
Sulieman, JS1

Trials

1 trial available for fluorouracil and Urethral Diseases

ArticleYear
Treatment of urethral condylomata acuminata or flat condylomata with interferon-alpha 2a.
    The Journal of urology, 1994, Volume: 152, Issue:6 Pt 1

    Topics: Condylomata Acuminata; Fluorouracil; Follow-Up Studies; Humans; Interferon alpha-2; Interferon-alpha

1994

Other Studies

9 other studies available for fluorouracil and Urethral Diseases

ArticleYear
Successfully treated urethral condyloma acuminatum utilizing intraurethral self-application of 5-fluorouracil via Q-tip.
    The Canadian journal of urology, 2022, Volume: 29, Issue:5

    Topics: Administration, Topical; Condylomata Acuminata; Female; Fluorouracil; Humans; Urethra; Urethral Dise

2022
Holmium:YAG laser ablation combined intraurethral fluorouracil perfusion as treatment option for intraurethral Condyloma acuminata in men.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2014, Volume: 66, Issue:1

    Topics: Adult; Combined Modality Therapy; Condylomata Acuminata; Fluorouracil; Humans; Laser Therapy; Lasers

2014
Intraurethral fluorouracil and lidocaine for intraurethral condyloma acuminata.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Oct-01, Volume: 65, Issue:19

    Topics: Administration, Topical; Anesthetics, Local; Condylomata Acuminata; Drug Therapy, Combination; Fluor

2008
[Diagnosis and treatment of urethral condyloma acuminatum in male patients].
    Zhonghua nan ke xue = National journal of andrology, 2002, Volume: 8, Issue:2

    Topics: Condylomata Acuminata; Fluorouracil; Follow-Up Studies; Humans; Instillation, Drug; Male; Treatment

2002
Pan-urethral wart treated with 5-fluorouracil intraurethral instillation.
    Journal of the Chinese Medical Association : JCMA, 2006, Volume: 69, Issue:8

    Topics: Adult; Fluorouracil; Humans; Male; Urethral Diseases; Warts

2006
Pan-urethral warts as a cause of acute retention of urine.
    BJU international, 1999, Volume: 84, Issue:9

    Topics: Adult; Antimetabolites, Antineoplastic; Condylomata Acuminata; Fluorouracil; Humans; Male; Recurrenc

1999
5-Fluoro-uracil cream in the successful treatment of therapeutically refractory condylomata acuminata of the urinary meatus.
    Acta dermato-venereologica, 1976, Volume: 56, Issue:4

    Topics: Administration, Topical; Condylomata Acuminata; Drug Evaluation; Fluorouracil; Humans; Male; Ointmen

1976
The eradication of intraurethral condyloma acuminata with 5 per cent 5-fluorouracil cream.
    The Journal of urology, 1975, Volume: 113, Issue:2

    Topics: Adult; Condylomata Acuminata; Fluorouracil; Follow-Up Studies; Humans; Male; Ointments; Urethral Dis

1975
Condyloma acuminatum of male urethra. Successful management with 5-fluorouracil.
    Urology, 1974, Volume: 3, Issue:4

    Topics: Adult; Condylomata Acuminata; Diverticulum; Fistula; Fluorouracil; Humans; Male; Neoplasm Recurrence

1974