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fluorouracil and Ureteral Neoplasms

fluorouracil has been researched along with Ureteral Neoplasms in 13 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Ureteral Neoplasms: Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.

Research Excerpts

ExcerptRelevanceReference
"Two VPM-CisCF chemotherapy regimens (vincristine (VCR), peplomycin (PEP), methotrexate (MTX), cis-diamminedichloroplatinum (II) (CDDP), cytosine arabinoside (Ara-C) and 5-fluorouracil (5-FU), established using human bladder cancer xenografts in nude mice were applied for advanced urothelial cancer."3.67[Sequential combination chemotherapy consisting of vincristine, peplomycin, methotrexate, cis-diamminedichloroplatinum (II), cytosine arabinoside and 5-fluorouracil, for advanced urothelial cancer]. ( Hida, S; Okada, K; Ooishi, K; Yamauchi, T; Yoshida, O, 1985)
"We report two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia."1.35[Two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia]. ( Kobayashi, Y; Matsuzaki, A; Terauchi, F; Washino, S, 2008)
"A case of primary squamous cell carcinoma of the ureter is reported."1.30[A case of primary squamous cell carcinoma of the ureter: biochemical modulation with cisplatin and 5-fluorouracil]. ( Kageyama, S; Ueda, T, 1997)
"The histopathological diagnosis was squamous cell carcinoma of the ureter, G1 INF beta, pT2, pR0, pV1 and pL0."1.30[A case of advanced primary ureteral squamous cell carcinoma responding to combination chemotherapy with cisplatin and 5-fluorouracil]. ( Fujita, T; Mori, H; Nakamura, Y; Noguchi, M; Okada, K, 1997)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's6 (46.15)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huelster, HL1
Hogan, MMS1
Resnick, MJ1
Washino, S1
Terauchi, F1
Matsuzaki, A1
Kobayashi, Y1
Lin, CC1
Hsu, CH1
Huang, CY1
Tsai, YC1
Huang, KH1
Cheng, AL1
Pu, YS1
Fujioka, H2
Tada, Y1
Nakano, E1
Matsuda, M1
Osafune, M2
Sagawa, S1
Takaha, M1
Sonoda, T1
Kotake, T1
Usami, M1
Miki, T1
Kuroda, M1
Obata, K1
Takasugi, Y1
Okamoto, T1
Noguchi, Y1
Yoshikawa, T1
Nomura, K1
Fukuzawa, K1
Uranaka, Y1
Makino, T1
Tsuburaya, A1
Amano, T1
Matsumoto, A1
Kageyama, S1
Ueda, T1
Fujita, T1
Mori, H1
Noguchi, M1
Nakamura, Y1
Okada, K3
Uekado, Y1
Hirano, A1
Shinka, T1
Ohkawa, T1
Nishiyama, T1
Sasagawa, T1
Tanikawa, T1
Katayama, Y1
Kawakami, Y1
Tomita, Y1
Terunuma, M1
Kimura, M1
Sato, S1
Osawa, T1
Kanimoto, Y1
Suzuki, Y1
Miwa, Y1
Akino, H1
Isomatu, Y1
Yamauchi, T1
Hida, S1
Ooishi, K1
Yoshida, O1
Ueda, K1
Jinno, H1
Watanabe, H1
Ohtaguro, K1

Trials

2 trials available for fluorouracil and Ureteral Neoplasms

ArticleYear
Prognostic factors for metastatic urothelial carcinoma treated with cisplatin and 5-fluorouracil-based regimens.
    Urology, 2007, Volume: 69, Issue:3

    Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Agents; Cisplatin; Female; Fluorouracil; Humans; K

2007
Results of adjuvant chemotherapy for invasive uroepithelial cancer.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30 Suppl

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cis

1992

Other Studies

11 other studies available for fluorouracil and Ureteral Neoplasms

ArticleYear
Acute Renal Transplant Failure Secondary to an Obstructing Ileal Conduit Adenocarcinoma: Case Report and Literature Review.
    Urology, 2019, Volume: 134

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Disease Progress

2019
[Two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2008, Volume: 99, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

2008
[Combination chemotherapy of advanced transitional cell carcinoma with cis-platinum, cyclophosphamide, adriamycin and 5-fluorouracil (CISCAF)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin

1984
Combination chemotherapy including adriamycin for advanced transitional cell carcinoma of the urinary tract.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Transitional Ce

1983
[Chemotherapy-induced thrombotic occlusion of mesenteric arteries--case report and review of the literature].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:8

    Topics: Abdomen, Acute; Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisp

1994
[A case of primary squamous cell carcinoma of the ureter: biochemical modulation with cisplatin and 5-fluorouracil].
    Hinyokika kiyo. Acta urologica Japonica, 1997, Volume: 43, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1997
[A case of advanced primary ureteral squamous cell carcinoma responding to combination chemotherapy with cisplatin and 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1997
[Sequential methotrexate and 5-fluorouracil, doxorubicin, and cisplatin for advanced urothelial cancer].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1992, Volume: 83, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc

1992
[Thymidylate synthase inhibition and concentration of 5-fluorouracil after administration of UFT in human uroepithelial carcinomas].
    Hinyokika kiyo. Acta urologica Japonica, 1991, Volume: 37, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto

1991
[Sequential combination chemotherapy consisting of vincristine, peplomycin, methotrexate, cis-diamminedichloroplatinum (II), cytosine arabinoside and 5-fluorouracil, for advanced urothelial cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:7

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous

1985
[Combination effects of CDDP, ACR and HCFU on progressive urothelial tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:6

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administra

1985