fluorouracil has been researched along with Ureteral Neoplasms in 13 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Ureteral Neoplasms: Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two VPM-CisCF chemotherapy regimens (vincristine (VCR), peplomycin (PEP), methotrexate (MTX), cis-diamminedichloroplatinum (II) (CDDP), cytosine arabinoside (Ara-C) and 5-fluorouracil (5-FU), established using human bladder cancer xenografts in nude mice were applied for advanced urothelial cancer." | 3.67 | [Sequential combination chemotherapy consisting of vincristine, peplomycin, methotrexate, cis-diamminedichloroplatinum (II), cytosine arabinoside and 5-fluorouracil, for advanced urothelial cancer]. ( Hida, S; Okada, K; Ooishi, K; Yamauchi, T; Yoshida, O, 1985) |
| "We report two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia." | 1.35 | [Two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia]. ( Kobayashi, Y; Matsuzaki, A; Terauchi, F; Washino, S, 2008) |
| "A case of primary squamous cell carcinoma of the ureter is reported." | 1.30 | [A case of primary squamous cell carcinoma of the ureter: biochemical modulation with cisplatin and 5-fluorouracil]. ( Kageyama, S; Ueda, T, 1997) |
| "The histopathological diagnosis was squamous cell carcinoma of the ureter, G1 INF beta, pT2, pR0, pV1 and pL0." | 1.30 | [A case of advanced primary ureteral squamous cell carcinoma responding to combination chemotherapy with cisplatin and 5-fluorouracil]. ( Fujita, T; Mori, H; Nakamura, Y; Noguchi, M; Okada, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huelster, HL | 1 |
| Hogan, MMS | 1 |
| Resnick, MJ | 1 |
| Washino, S | 1 |
| Terauchi, F | 1 |
| Matsuzaki, A | 1 |
| Kobayashi, Y | 1 |
| Lin, CC | 1 |
| Hsu, CH | 1 |
| Huang, CY | 1 |
| Tsai, YC | 1 |
| Huang, KH | 1 |
| Cheng, AL | 1 |
| Pu, YS | 1 |
| Fujioka, H | 2 |
| Tada, Y | 1 |
| Nakano, E | 1 |
| Matsuda, M | 1 |
| Osafune, M | 2 |
| Sagawa, S | 1 |
| Takaha, M | 1 |
| Sonoda, T | 1 |
| Kotake, T | 1 |
| Usami, M | 1 |
| Miki, T | 1 |
| Kuroda, M | 1 |
| Obata, K | 1 |
| Takasugi, Y | 1 |
| Okamoto, T | 1 |
| Noguchi, Y | 1 |
| Yoshikawa, T | 1 |
| Nomura, K | 1 |
| Fukuzawa, K | 1 |
| Uranaka, Y | 1 |
| Makino, T | 1 |
| Tsuburaya, A | 1 |
| Amano, T | 1 |
| Matsumoto, A | 1 |
| Kageyama, S | 1 |
| Ueda, T | 1 |
| Fujita, T | 1 |
| Mori, H | 1 |
| Noguchi, M | 1 |
| Nakamura, Y | 1 |
| Okada, K | 3 |
| Uekado, Y | 1 |
| Hirano, A | 1 |
| Shinka, T | 1 |
| Ohkawa, T | 1 |
| Nishiyama, T | 1 |
| Sasagawa, T | 1 |
| Tanikawa, T | 1 |
| Katayama, Y | 1 |
| Kawakami, Y | 1 |
| Tomita, Y | 1 |
| Terunuma, M | 1 |
| Kimura, M | 1 |
| Sato, S | 1 |
| Osawa, T | 1 |
| Kanimoto, Y | 1 |
| Suzuki, Y | 1 |
| Miwa, Y | 1 |
| Akino, H | 1 |
| Isomatu, Y | 1 |
| Yamauchi, T | 1 |
| Hida, S | 1 |
| Ooishi, K | 1 |
| Yoshida, O | 1 |
| Ueda, K | 1 |
| Jinno, H | 1 |
| Watanabe, H | 1 |
| Ohtaguro, K | 1 |
2 trials available for fluorouracil and Ureteral Neoplasms
| Article | Year |
|---|---|
Prognostic factors for metastatic urothelial carcinoma treated with cisplatin and 5-fluorouracil-based regimens.
Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Agents; Cisplatin; Female; Fluorouracil; Humans; K | 2007 |
Results of adjuvant chemotherapy for invasive uroepithelial cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cis | 1992 |
11 other studies available for fluorouracil and Ureteral Neoplasms
| Article | Year |
|---|---|
Acute Renal Transplant Failure Secondary to an Obstructing Ileal Conduit Adenocarcinoma: Case Report and Literature Review.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Disease Progress | 2019 |
[Two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 2008 |
[Combination chemotherapy of advanced transitional cell carcinoma with cis-platinum, cyclophosphamide, adriamycin and 5-fluorouracil (CISCAF)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin | 1984 |
Combination chemotherapy including adriamycin for advanced transitional cell carcinoma of the urinary tract.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Transitional Ce | 1983 |
[Chemotherapy-induced thrombotic occlusion of mesenteric arteries--case report and review of the literature].
Topics: Abdomen, Acute; Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisp | 1994 |
[A case of primary squamous cell carcinoma of the ureter: biochemical modulation with cisplatin and 5-fluorouracil].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 1997 |
[A case of advanced primary ureteral squamous cell carcinoma responding to combination chemotherapy with cisplatin and 5-fluorouracil].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 1997 |
[Sequential methotrexate and 5-fluorouracil, doxorubicin, and cisplatin for advanced urothelial cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc | 1992 |
[Thymidylate synthase inhibition and concentration of 5-fluorouracil after administration of UFT in human uroepithelial carcinomas].
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto | 1991 |
[Sequential combination chemotherapy consisting of vincristine, peplomycin, methotrexate, cis-diamminedichloroplatinum (II), cytosine arabinoside and 5-fluorouracil, for advanced urothelial cancer].
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous | 1985 |
[Combination effects of CDDP, ACR and HCFU on progressive urothelial tumors].
Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administra | 1985 |