fluorouracil and Trophoblastic Tumor, Placental Site
fluorouracil has been researched along with Trophoblastic Tumor, Placental Site in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Trophoblastic Tumor, Placental Site: An uncommon variant of CHORIOCARCINOMA. It is composed almost entirely of mononuclear cytotrophoblasts (TROPHOBLASTS). Because its secretion of hCG (CHORIONIC GONADOTROPIN) is low, a large tumor may develop before the hCG can be detected.
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhao, Y | 1 |
| Zhang, W | 1 |
| Duan, W | 1 |
| Yang, XY | 1 |
Other Studies
2 other studies available for fluorouracil and Trophoblastic Tumor, Placental Site
| Article | Year |
|---|---|
Management of gestational trophoblastic neoplasia with 5-fluorouracil and actinomycin D in northern China.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; China; Cohort Studies; Dactinomycin; Female; | 2009 |
[The necessity of attaching importance to canonical treatment of gestationcal trophoblastic tumors].
Topics: Antineoplastic Agents; Cyclophosphamide; Diagnosis, Differential; Drug Resistance, Neoplasm; Female; | 2005 |