fluorouracil has been researched along with Tracheal Stenosis in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Tracheal Stenosis: A pathological narrowing of the TRACHEA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to evaluate the efficacy of ethosomes encapsulated with 5-fluorouracil (5-FU) in treatment of laryngotracheal stenosis in rabbit models." | 7.85 | The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models. ( Cheng, X; Mao, X; Wang, Z; Zhang, Z, 2017) |
| "The purpose of our article was to explore the effect of ethosomes containing 5-fluorouracil (5-FU) with different sizes on laryngotracheal stenosis treatment." | 7.81 | A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil. ( Ao, H; Gu, J; Li, C; Mao, X; Yang, X, 2015) |
| "We aimed to investigate the prophylactic effect of pentoxifylline (PTX) and 5-fluorouracil (5-FU) on laryngotracheal stenosis in tracheotomised rats by evaluating blood glutathione peroxidase (GPx) and superoxide dismutase activities and by histopathological evaluation of laryngotracheal segment." | 7.78 | Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats. ( Ekici, A; Eyibilen, A; Kıyıcı, H; Koc, S; Salman, N; Söğüt, E, 2012) |
| "The severity of stenosis was observed under laryngofiberoscope immediately, 7, 14, 21 days after administration." | 5.38 | [Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit]. ( Ao, H; Cheng, X; Gu, J; Kong, D; Mao, X; Yang, X, 2012) |
| "The aim of this study is to evaluate the efficacy of ethosomes encapsulated with 5-fluorouracil (5-FU) in treatment of laryngotracheal stenosis in rabbit models." | 3.85 | The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models. ( Cheng, X; Mao, X; Wang, Z; Zhang, Z, 2017) |
| "The purpose of our article was to explore the effect of ethosomes containing 5-fluorouracil (5-FU) with different sizes on laryngotracheal stenosis treatment." | 3.81 | A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil. ( Ao, H; Gu, J; Li, C; Mao, X; Yang, X, 2015) |
| "We aimed to investigate the prophylactic effect of pentoxifylline (PTX) and 5-fluorouracil (5-FU) on laryngotracheal stenosis in tracheotomised rats by evaluating blood glutathione peroxidase (GPx) and superoxide dismutase activities and by histopathological evaluation of laryngotracheal segment." | 3.78 | Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats. ( Ekici, A; Eyibilen, A; Kıyıcı, H; Koc, S; Salman, N; Söğüt, E, 2012) |
| "The severity of stenosis was observed under laryngofiberoscope immediately, 7, 14, 21 days after administration." | 1.38 | [Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit]. ( Ao, H; Cheng, X; Gu, J; Kong, D; Mao, X; Yang, X, 2012) |
| "Frequently advanced or recurrent esophageal cancer was invasive trachea and often causing hemoptysis, stenosis and dyspnea." | 1.36 | [A case of recurrent esophageal cancer with tracheal invasion treated by chemo-radiotherapy (CRT) after placement of tracheal stent that maintained complete response (CR) for two years]. ( Amagasa, H; Ami, K; Ando, M; Arai, K; Fukuda, A; Ganno, H; Hataji, K; Kawasaki, Y; Kurokawa, T; Nagahama, T; Tei, S; Watayou, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, J | 2 |
| Mao, X | 3 |
| Li, C | 1 |
| Ao, H | 2 |
| Yang, X | 2 |
| Cheng, X | 2 |
| Zhang, Z | 1 |
| Wang, Z | 2 |
| Ami, K | 1 |
| Nagahama, T | 1 |
| Ando, M | 1 |
| Watayou, Y | 1 |
| Amagasa, H | 1 |
| Ganno, H | 1 |
| Hataji, K | 1 |
| Kawasaki, Y | 1 |
| Kurokawa, T | 1 |
| Fukuda, A | 1 |
| Tei, S | 1 |
| Arai, K | 1 |
| Guven, M | 1 |
| Turan, F | 1 |
| Eyibilen, A | 2 |
| Akbaş, A | 1 |
| Erkorkmaz, Ü | 1 |
| Koc, S | 1 |
| Kıyıcı, H | 1 |
| Söğüt, E | 1 |
| Ekici, A | 1 |
| Salman, N | 1 |
| Kong, D | 1 |
| Shitara, K | 1 |
| Munakata, M | 1 |
| Ishiguro, A | 1 |
| Hoshi, Y | 1 |
| Okada, R | 1 |
| Tomioka, R | 1 |
| Mitobe, S | 1 |
| Sakata, Y | 1 |
| Ebina, A | 1 |
| Aoki, M | 1 |
7 other studies available for fluorouracil and Tracheal Stenosis
| Article | Year |
|---|---|
A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil.
Topics: Animals; Disease Models, Animal; Female; Fluorouracil; Immunosuppressive Agents; Laryngostenosis; Li | 2015 |
The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models.
Topics: Animals; Antimetabolites; Drug Administration Schedule; Drug Delivery Systems; Female; Fluorouracil; | 2017 |
[A case of recurrent esophageal cancer with tracheal invasion treated by chemo-radiotherapy (CRT) after placement of tracheal stent that maintained complete response (CR) for two years].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2010 |
A comparison of the efficacy of 5-fluorouracil/triamcinolone, carnitine and dexamethasone therapy on wound healing in tracheal injury: potential for preventing tracheal stenosis?
Topics: Animals; Antimetabolites; Carnitine; Dexamethasone; Drug Combinations; Fluorouracil; Glucocorticoids | 2012 |
Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats.
Topics: Animals; Biological Availability; Female; Fluorouracil; Glucocorticoids; Glutathione Peroxidase; Imm | 2012 |
[Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit].
Topics: Animals; Constriction, Pathologic; Fluorouracil; Liposomes; Rabbits; Tracheal Stenosis | 2012 |
[A case of advanced esophageal cancer with suspected tracheoesophageal fistula that responded to chemoradiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administr | 2006 |