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fluorouracil and Tracheal Stenosis

fluorouracil has been researched along with Tracheal Stenosis in 7 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Tracheal Stenosis: A pathological narrowing of the TRACHEA.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study is to evaluate the efficacy of ethosomes encapsulated with 5-fluorouracil (5-FU) in treatment of laryngotracheal stenosis in rabbit models."7.85The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models. ( Cheng, X; Mao, X; Wang, Z; Zhang, Z, 2017)
"The purpose of our article was to explore the effect of ethosomes containing 5-fluorouracil (5-FU) with different sizes on laryngotracheal stenosis treatment."7.81A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil. ( Ao, H; Gu, J; Li, C; Mao, X; Yang, X, 2015)
"We aimed to investigate the prophylactic effect of pentoxifylline (PTX) and 5-fluorouracil (5-FU) on laryngotracheal stenosis in tracheotomised rats by evaluating blood glutathione peroxidase (GPx) and superoxide dismutase activities and by histopathological evaluation of laryngotracheal segment."7.78Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats. ( Ekici, A; Eyibilen, A; Kıyıcı, H; Koc, S; Salman, N; Söğüt, E, 2012)
"The severity of stenosis was observed under laryngofiberoscope immediately, 7, 14, 21 days after administration."5.38[Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit]. ( Ao, H; Cheng, X; Gu, J; Kong, D; Mao, X; Yang, X, 2012)
"The aim of this study is to evaluate the efficacy of ethosomes encapsulated with 5-fluorouracil (5-FU) in treatment of laryngotracheal stenosis in rabbit models."3.85The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models. ( Cheng, X; Mao, X; Wang, Z; Zhang, Z, 2017)
"The purpose of our article was to explore the effect of ethosomes containing 5-fluorouracil (5-FU) with different sizes on laryngotracheal stenosis treatment."3.81A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil. ( Ao, H; Gu, J; Li, C; Mao, X; Yang, X, 2015)
"We aimed to investigate the prophylactic effect of pentoxifylline (PTX) and 5-fluorouracil (5-FU) on laryngotracheal stenosis in tracheotomised rats by evaluating blood glutathione peroxidase (GPx) and superoxide dismutase activities and by histopathological evaluation of laryngotracheal segment."3.78Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats. ( Ekici, A; Eyibilen, A; Kıyıcı, H; Koc, S; Salman, N; Söğüt, E, 2012)
"The severity of stenosis was observed under laryngofiberoscope immediately, 7, 14, 21 days after administration."1.38[Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit]. ( Ao, H; Cheng, X; Gu, J; Kong, D; Mao, X; Yang, X, 2012)
"Frequently advanced or recurrent esophageal cancer was invasive trachea and often causing hemoptysis, stenosis and dyspnea."1.36[A case of recurrent esophageal cancer with tracheal invasion treated by chemo-radiotherapy (CRT) after placement of tracheal stent that maintained complete response (CR) for two years]. ( Amagasa, H; Ami, K; Ando, M; Arai, K; Fukuda, A; Ganno, H; Hataji, K; Kawasaki, Y; Kurokawa, T; Nagahama, T; Tei, S; Watayou, Y, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gu, J2
Mao, X3
Li, C1
Ao, H2
Yang, X2
Cheng, X2
Zhang, Z1
Wang, Z2
Ami, K1
Nagahama, T1
Ando, M1
Watayou, Y1
Amagasa, H1
Ganno, H1
Hataji, K1
Kawasaki, Y1
Kurokawa, T1
Fukuda, A1
Tei, S1
Arai, K1
Guven, M1
Turan, F1
Eyibilen, A2
Akbaş, A1
Erkorkmaz, Ü1
Koc, S1
Kıyıcı, H1
Söğüt, E1
Ekici, A1
Salman, N1
Kong, D1
Shitara, K1
Munakata, M1
Ishiguro, A1
Hoshi, Y1
Okada, R1
Tomioka, R1
Mitobe, S1
Sakata, Y1
Ebina, A1
Aoki, M1

Other Studies

7 other studies available for fluorouracil and Tracheal Stenosis

ArticleYear
A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil.
    The Annals of otology, rhinology, and laryngology, 2015, Volume: 124, Issue:7

    Topics: Animals; Disease Models, Animal; Female; Fluorouracil; Immunosuppressive Agents; Laryngostenosis; Li

2015
The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2017, Volume: 274, Issue:4

    Topics: Animals; Antimetabolites; Drug Administration Schedule; Drug Delivery Systems; Female; Fluorouracil;

2017
[A case of recurrent esophageal cancer with tracheal invasion treated by chemo-radiotherapy (CRT) after placement of tracheal stent that maintained complete response (CR) for two years].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2010
A comparison of the efficacy of 5-fluorouracil/triamcinolone, carnitine and dexamethasone therapy on wound healing in tracheal injury: potential for preventing tracheal stenosis?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012, Volume: 269, Issue:1

    Topics: Animals; Antimetabolites; Carnitine; Dexamethasone; Drug Combinations; Fluorouracil; Glucocorticoids

2012
Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012, Volume: 269, Issue:7

    Topics: Animals; Biological Availability; Female; Fluorouracil; Glucocorticoids; Glutathione Peroxidase; Imm

2012
[Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2012, Volume: 26, Issue:20

    Topics: Animals; Constriction, Pathologic; Fluorouracil; Liposomes; Rabbits; Tracheal Stenosis

2012
[A case of advanced esophageal cancer with suspected tracheoesophageal fistula that responded to chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administr

2006