fluorouracil has been researched along with Torsade de Pointes in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, RY | 1 |
| Lee, MY | 1 |
| Kan, CB | 1 |
| Hsu, WP | 1 |
| Hsiao, PC | 1 |
| Kim, HJ | 1 |
| An, SH | 1 |
| Cho, YH | 1 |
| Kim, SY | 1 |
| Lee, HG | 1 |
| Yoon, SY | 1 |
2 other studies available for fluorouracil and Torsade de Pointes
| Article | Year |
|---|---|
Oxaliplatin-induced acquired long QT syndrome with torsades de pointes and myocardial injury in a patient with dilated cardiomyopathy and rectal cancer.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathy, Dilated | 2013 |
Oxaliplatin-induced Torsades de pointes and long QT syndrome in a patient with gastric cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Long QT Synd | 2013 |