fluorouracil has been researched along with Thyroid Diseases in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Thyroid Diseases: Pathological processes involving the THYROID GLAND.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Narula, HS | 1 |
| Carlson, HE | 1 |
| Olver, JM | 1 |
| Rose, GE | 1 |
| Khaw, PT | 1 |
| Collin, JR | 1 |
1 trial available for fluorouracil and Thyroid Diseases
| Article | Year |
|---|---|
Correction of lower eyelid retraction in thyroid eye disease: a randomised controlled trial of retractor tenotomy with adjuvant antimetabolite versus scleral graft.
Topics: Adult; Aged; Antimetabolites; Eyelid Diseases; Female; Fluorouracil; Humans; Male; Middle Aged; Mito | 1998 |
1 other study available for fluorouracil and Thyroid Diseases
| Article | Year |
|---|---|
Capecitabine-induced abnormalities in thyroid function tests.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Middle A | 2004 |