fluorouracil has been researched along with Thrombophilia in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Thrombophilia: A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Also, as the veins in the lower extremity were filled with thrombus, we gave him an anticoagulant (Edoxaban), but due to the malignant hyper coagulable state (Trousseau syndrome) a CV port could not be implanted." | 3.91 | [A Case Report of Luminal A Male Inflammatory Breast Cancer that Was Difficult to Treat Because of Trousseau Syndrome]. ( Hirai, A; Ichiki, Y; Imanishi, N; Ishida, T; Kusanagi, K; Shinohara, S; Takeda, Y; Tanaka, F; Tashima, Y; Yoshimatsu, K, 2019) |
| "Patients with metastatic colorectal cancer received either FOLFOX-4 + bev or FOLFIRI + bev." | 2.75 | Management of venous thromboembolism in colorectal cancer patients treated with bevacizumab. ( Chin, K; Fujiwara, Y; Hatake, K; Ichimura, T; Kobayashi, K; Konishi, F; Kuboki, Y; Matsueda, K; Matsusaka, S; Mizunuma, N; Ogura, M; Ozaka, M; Shinozaki, E; Suenaga, M, 2010) |
| "In 71 patients with esophageal cancer who underwent neoadjuvant chemotherapy (cisplatin, adriamycin and 5-fluorouracil) followed by surgery, plasma d-dimer levels were measured before chemotherapy and the clinical and pathological responses to chemotherapy were assessed at 4 weeks after therapy (after surgery)." | 1.35 | Correlation between pretherapeutic d-dimer levels and response to neoadjuvant chemotherapy in patients with advanced esophageal cancer. ( Imaoka, S; Ishikawa, O; Kishi, K; Miyashiro, I; Ohigashi, H; Ohue, M; Sasaki, Y; Takachi, K; Tomimaru, Y; Yano, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tashima, Y | 1 |
| Kusanagi, K | 1 |
| Takeda, Y | 1 |
| Yoshimatsu, K | 1 |
| Ishida, T | 1 |
| Shinohara, S | 1 |
| Hirai, A | 1 |
| Imanishi, N | 1 |
| Ichiki, Y | 1 |
| Tanaka, F | 1 |
| Suenaga, M | 1 |
| Mizunuma, N | 1 |
| Kobayashi, K | 1 |
| Shinozaki, E | 1 |
| Matsusaka, S | 1 |
| Chin, K | 1 |
| Kuboki, Y | 1 |
| Ichimura, T | 1 |
| Ozaka, M | 1 |
| Ogura, M | 1 |
| Fujiwara, Y | 1 |
| Matsueda, K | 1 |
| Konishi, F | 1 |
| Hatake, K | 1 |
| Wang, PL | 1 |
| Cheng, YB | 1 |
| Kuerban, G | 1 |
| Shah, SM | 1 |
| Drage, MG | 1 |
| Lichtman, AH | 1 |
| Haddad, RI | 1 |
| Ely, SF | 1 |
| Tomimaru, Y | 1 |
| Yano, M | 1 |
| Takachi, K | 1 |
| Kishi, K | 1 |
| Miyashiro, I | 1 |
| Ohue, M | 1 |
| Ohigashi, H | 1 |
| Sasaki, Y | 1 |
| Ishikawa, O | 1 |
| Imaoka, S | 1 |
1 trial available for fluorouracil and Thrombophilia
| Article | Year |
|---|---|
Management of venous thromboembolism in colorectal cancer patients treated with bevacizumab.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies | 2010 |
5 other studies available for fluorouracil and Thrombophilia
| Article | Year |
|---|---|
[A Case Report of Luminal A Male Inflammatory Breast Cancer that Was Difficult to Treat Because of Trousseau Syndrome].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Cilostazol; Combined M | 2019 |
The clinical characteristic differences between thrombosis-related edema and lymphedema following radiotherapy or chemoradiotherapy for patients with cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy | 2012 |
Metastatic human papillomavirus-positive nasopharyngeal carcinoma with an unusual pattern of aggressive hematogenous spread.
Topics: Alphapapillomavirus; Antineoplastic Combined Chemotherapy Protocols; Axilla; Biomarkers, Tumor; Carb | 2012 |
Potential risk of a common hereditary thrombophilia and adjuvant chemotherapy for low-stage breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosp | 2005 |
Correlation between pretherapeutic d-dimer levels and response to neoadjuvant chemotherapy in patients with advanced esophageal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Doxorubicin; Esophageal Neoplasms; Female; Fibrin Fib | 2008 |