fluorouracil has been researched along with Thromboembolism, Venous in 19 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report our experience with 2 male patients (71 and 74 years old, respectively) with advanced esophageal cancer who exhibited pulmonary embolism during treatment with neoadjuvant chemotherapy with cisplatin (CDDP) and 5-fluorouracil (5- FU)." | 3.80 | [Pulmonary embolism in esophageal cancer patients receiving neoadjuvant chemotherapy with CDDP and 5-FU]. ( Fujiwara, H; Ichikawa, D; Ikoma, H; Kitagawa, M; Komatsu, S; Konishi, H; Kuriu, Y; Murayama, Y; Nakanishi, M; Okamoto, K; Otsuji, E; Sakakura, C; Shiozaki, A, 2014) |
| "Patients with metastatic colorectal cancer received either FOLFOX-4 + bev or FOLFIRI + bev." | 2.75 | Management of venous thromboembolism in colorectal cancer patients treated with bevacizumab. ( Chin, K; Fujiwara, Y; Hatake, K; Ichimura, T; Kobayashi, K; Konishi, F; Kuboki, Y; Matsueda, K; Matsusaka, S; Mizunuma, N; Ogura, M; Ozaka, M; Shinozaki, E; Suenaga, M, 2010) |
| "Advanced pancreatic cancer, in addition to its high mortality, is characterized by one of the highest rates of venous thromboembolic events (VTE) as compared to other types of cancer." | 2.73 | Rationale and design of PROSPECT-CONKO 004: a prospective, randomized trial of simultaneous pancreatic cancer treatment with enoxaparin and chemotherapy). ( Bramlage, P; Dörken, B; Hilbig, A; Kauschat-Brüning, D; Oettle, H; Opitz, B; Pelzer, U; Riess, H; Scholten, T; Stieler, J, 2008) |
| "She was diagnosed with ascending colon cancer, with portal vein tumor thromboembolism extending to the portosplenic junction." | 2.52 | [Five-Year Recurrence-Free Survival after mFOLFOX6 Administration, Right Hemicolectomy, and Lymphadenectomy for Portal Venous Tumor Thromboembolism]. ( Asayama, M; Ishikawa, H; Kawashima, Y; Mori, Y; Nishimura, Y; Nishizawa, Y; Sakamoto, H; Takano, M; Takenoya, T; Tanaka, Y, 2015) |
| "The risk of venous thromboembolism has been reported to increase when receiving bevacizumab." | 1.36 | Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab. ( Doi, T; Fuse, N; Ikematsu, H; Kaneko, K; Koike, K; Kojima, T; Minashi, K; Mochizuki, S; Ohtsu, A; Tahara, M; Yano, T; Yoshino, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Q | 1 |
| Cui, SP | 1 |
| Wang, D | 1 |
| Lang, R | 1 |
| Jimi, S | 1 |
| Oohata, Y | 1 |
| Tamura, T | 1 |
| Takahata, S | 1 |
| Kamei, T | 1 |
| Otten, JMMB | 1 |
| Fijnheer, R | 1 |
| Riedl, JM | 1 |
| Schwarzenbacher, E | 1 |
| Moik, F | 1 |
| Horvath, L | 1 |
| Gantschnigg, A | 1 |
| Renneberg, F | 1 |
| Posch, F | 1 |
| Barth, DA | 1 |
| Stotz, M | 1 |
| Pichler, M | 1 |
| Hatzl, S | 1 |
| Fandler-Höfler, S | 1 |
| Gressenberger, P | 1 |
| Gary, T | 1 |
| Jost, PJ | 1 |
| Greil, R | 1 |
| Ay, C | 1 |
| Djanani, A | 1 |
| Gerger, A | 1 |
| Schlick, K | 1 |
| Abdel-Rahman, O | 1 |
| Wu, C | 1 |
| Easaw, J | 1 |
| Khanna, A | 1 |
| Reece-Smith, AM | 1 |
| Cunnell, M | 1 |
| Madhusudan, S | 1 |
| Thomas, A | 1 |
| Bowrey, DJ | 1 |
| Parsons, SL | 1 |
| Roselli, M | 1 |
| Ferroni, P | 1 |
| Rolfo, C | 1 |
| Peeters, M | 1 |
| Palmirotta, R | 1 |
| Formica, V | 1 |
| Ludovici, G | 1 |
| Laudisi, A | 1 |
| De Marchis, ML | 1 |
| La Farina, F | 1 |
| Russo, A | 1 |
| Guadagni, F | 1 |
| Muñoz Martín, AJ | 1 |
| García Alfonso, P | 1 |
| Rupérez Blanco, AB | 1 |
| Pérez Ramírez, S | 1 |
| Blanco Codesido, M | 1 |
| Martín Jiménez, M | 1 |
| Giuliani, J | 1 |
| Martelli, S | 1 |
| Piacentini, P | 1 |
| Bonetti, A | 1 |
| Kitagawa, M | 1 |
| Shiozaki, A | 1 |
| Fujiwara, H | 1 |
| Konishi, H | 1 |
| Komatsu, S | 1 |
| Ichikawa, D | 1 |
| Okamoto, K | 1 |
| Murayama, Y | 1 |
| Kuriu, Y | 1 |
| Ikoma, H | 1 |
| Nakanishi, M | 1 |
| Sakakura, C | 1 |
| Otsuji, E | 1 |
| Nishimura, Y | 1 |
| Nishizawa, Y | 1 |
| Ishikawa, H | 1 |
| Mori, Y | 1 |
| Takano, M | 1 |
| Takenoya, T | 1 |
| Asayama, M | 1 |
| Kawashima, Y | 1 |
| Sakamoto, H | 1 |
| Tanaka, Y | 1 |
| Riess, H | 1 |
| Pelzer, U | 1 |
| Hilbig, A | 1 |
| Stieler, J | 1 |
| Opitz, B | 1 |
| Scholten, T | 1 |
| Kauschat-Brüning, D | 1 |
| Bramlage, P | 1 |
| Dörken, B | 1 |
| Oettle, H | 1 |
| Mandalà, M | 1 |
| Barni, S | 1 |
| Floriani, I | 1 |
| Isa, L | 1 |
| Fornarini, G | 1 |
| Marangolo, M | 1 |
| Mosconi, S | 1 |
| Corsi, D | 1 |
| Rulli, E | 1 |
| Frontini, L | 1 |
| Cortesi, E | 1 |
| Zaniboni, A | 1 |
| Aglietta, M | 1 |
| Labianca, R | 1 |
| Kilickap, S | 1 |
| Arslan, C | 1 |
| Suenaga, M | 1 |
| Mizunuma, N | 1 |
| Kobayashi, K | 1 |
| Shinozaki, E | 1 |
| Matsusaka, S | 1 |
| Chin, K | 1 |
| Kuboki, Y | 1 |
| Ichimura, T | 1 |
| Ozaka, M | 1 |
| Ogura, M | 1 |
| Fujiwara, Y | 1 |
| Matsueda, K | 1 |
| Konishi, F | 1 |
| Hatake, K | 1 |
| Mochizuki, S | 1 |
| Yoshino, T | 1 |
| Kojima, T | 1 |
| Fuse, N | 1 |
| Ikematsu, H | 1 |
| Minashi, K | 1 |
| Yano, T | 1 |
| Tahara, M | 1 |
| Kaneko, K | 1 |
| Doi, T | 1 |
| Koike, K | 1 |
| Ohtsu, A | 1 |
| Nobili, E | 1 |
| Di Cicilia, R | 1 |
| Di Battista, M | 1 |
| Morselli-Labate, AM | 1 |
| Paragona, M | 1 |
| Corbelli, J | 1 |
| Macchini, M | 1 |
| Prandoni, P | 1 |
| Biasco, G | 1 |
| Brandi, G | 1 |
| Rollins, KE | 1 |
| Peters, CJ | 1 |
| Safranek, PM | 1 |
| Ford, H | 1 |
| Baglin, TP | 1 |
| Hardwick, RH | 1 |
| Strimpakos, AS | 1 |
| Syrigos, KN | 1 |
| Saif, MW | 1 |
1 review available for fluorouracil and Thromboembolism, Venous
| Article | Year |
|---|---|
[Five-Year Recurrence-Free Survival after mFOLFOX6 Administration, Right Hemicolectomy, and Lymphadenectomy for Portal Venous Tumor Thromboembolism].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colon, Ascending; Colonic Neoplasms | 2015 |
3 trials available for fluorouracil and Thromboembolism, Venous
| Article | Year |
|---|---|
Rationale and design of PROSPECT-CONKO 004: a prospective, randomized trial of simultaneous pancreatic cancer treatment with enoxaparin and chemotherapy).
Topics: Adolescent; Adult; Animals; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Cisplati | 2008 |
Incidence and clinical implications of venous thromboembolism in advanced colorectal cancer patients: the 'GISCAD-alternating schedule' study findings.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administrati | 2009 |
Management of venous thromboembolism in colorectal cancer patients treated with bevacizumab.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies | 2010 |
15 other studies available for fluorouracil and Thromboembolism, Venous
| Article | Year |
|---|---|
Is new risk-assessment score of venous thromboembolism for hospitalized surgical patients with borderline resectable pancreatic adenocarcinoma needed?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Fluoro | 2023 |
[Successful Management of Deep Vein Thromboembolism and Pulmonary Embolism by Edoxaban for Long-Term 5-FU-Based Chemotherapy for Colon Cancer-A Case Report].
Topics: Aged; Anticoagulants; Colonic Neoplasms; Fluorouracil; Humans; Pulmonary Embolism; Pyridines; Thiazo | 2019 |
[Whether or not to use thromboprophylaxis in patients treated with chemotherapy for malignant disease].
Topics: Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemopreventi | 2019 |
Patterns of Thromboembolism in Patients with Advanced Pancreatic Cancer Undergoing First-Line Chemotherapy with FOLFIRINOX or Gemcitabine/nab-Paclitaxel.
Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Fluorouracil; Gemcitabine; | 2022 |
Risk of arterial and venous thromboembolic events among patients with colorectal carcinoma: a real-world, population-based study.
Topics: Aged; Aged, 80 and over; Colorectal Neoplasms; Female; Fluorouracil; Humans; Logistic Models; Male; | 2021 |
Venous thromboembolism in patients receiving perioperative chemotherapy for esophagogastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape | 2014 |
TNF-α gene promoter polymorphisms and risk of venous thromboembolism in gastrointestinal cancer patients undergoing chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; | 2013 |
Incidence of venous thromboembolism (VTE) in ambulatory pancreatic cancer patients receiving chemotherapy and analysis of Khorana's predictive model.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreati | 2014 |
Thromboembolic disease in advanced colorectal cancer treated with chemotherapy and bevacizumab: a case of real "pan-thrombosis".
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro | 2015 |
[Pulmonary embolism in esophageal cancer patients receiving neoadjuvant chemotherapy with CDDP and 5-FU].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Venous Catheters; Cisplatin; Esophagea | 2014 |
Risk of venous thromboembolism with bevacizumab in cancer patients.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A | 2009 |
Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplast | 2010 |
Venous thromboembolism and port-related thrombosis in metastatic colorectal cancer patients: a monocenter experience.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap | 2010 |
Venous thromboembolism in oesophago-gastric carcinoma: incidence of symptomatic and asymptomatic events following chemotherapy and surgery.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Cape | 2011 |
Clinical and laboratory biomarkers in the management of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Bevacizumab; Biomarkers; Capecitabine; Deoxycytid | 2012 |