Page last updated: 2024-10-27

fluorouracil and Thrombocytopathy

fluorouracil has been researched along with Thrombocytopathy in 5 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
EISMAN, SG1
RICHARDSON, FM1
Shiu, MH1
Fortner, JG1
Cedermark, BJ1
Didolkar, MS1
Elias, EG1
Gynn, TN1
Messmore, HL1
Friedman, IA1
Piro, AJ1
Wilson, RE1
Hall, TC1
Aliapoulios, MA1
Nevinny, HB1
Moore, FD1

Reviews

1 review available for fluorouracil and Thrombocytopathy

ArticleYear
Drug-induced thrombocytopenia.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Aged; Agglutination Tests; Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Ant

1972

Trials

1 trial available for fluorouracil and Thrombocytopathy

ArticleYear
Methyl-CCNU (NSC-95441) in advanced colorectal carcinoma after failure of 5-fluorouracil (NSC-19893) therapy.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Blood Platelet Disorders; Clinical Trials as Topic; Colonic Neoplasms;

1976

Other Studies

3 other studies available for fluorouracil and Thrombocytopathy

ArticleYear
CANCER CHEMOTHERAPY.
    Medical science, 1964, Volume: 15

    Topics: Adrenal Cortex Hormones; Aminopterin; Androgens; Antimetabolites; Antineoplastic Agents; Blood Plate

1964
Current management of hepatic tumors.
    Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:5

    Topics: Angiography; Biopsy, Needle; Blood Platelet Disorders; Carcinoma, Hepatocellular; Child; Child, Pres

1975
Toxicity studies of fluorouracil used with adrenalectomy in breast cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 105, Issue:1

    Topics: Adrenalectomy; Adult; Aged; Alopecia; Ataxia; Blood Platelet Disorders; Breast Neoplasms; Diarrhea;

1972