fluorouracil has been researched along with Testicular Neoplasms in 47 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At this juncture in the development of paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ), knowledge about the agent's pharmacologic behavior and clinical antitumor activity in less common neoplasms is being elucidated." | 4.79 | Paclitaxel pharmacology and other tumor types. ( Rowinsky, EK, 1997) |
| "A 57-year-old woman developed severe tumor lysis syndrome characterized by acute hyperuricemic nephropathy, hyperphosphatemia, hyperkalemia, and hypocalcemia after therapy with cyclophosphamide, methotrexate, and 5-fluorouracil for metastatic infiltrating ductal carcinoma of the breast involving the chest wall, lungs, pleurae, and liver." | 3.67 | Tumor lysis syndrome in nonhematopoietic neoplasms. ( Barton, JC, 1989) |
| "Capecitabine was well tolerated, but is not effective in heavily pretreated patients with cisplatin-refractory or relapsed germ cell tumors." | 2.73 | An open-label, multicenter phase II trial of capecitabine in patients with cisplatin-refractory or relapsed germ cell tumors. ( Bokemeyer, C; Grünwald, V; Hartmann, JT; Honecker, F; Kollmannsberger, C; Mayer, F; Oechsle, K; Rick, O, 2007) |
| "Concerning penis cancer, the optimal protocols validated by a high level of evidence are missing." | 2.49 | [Chemotherapy in male external genital organs (testicular and penile cancer)]. ( Bastide, C; Bruyère, F; Deville, JL; Flechon, A; Guy, L; Karsenty, G, 2013) |
| "A case of pure, primary testicular carcinoid tumor in a 27-seven-year-old male is reported." | 2.37 | [Primary carcinoid tumor of the testis: a case report]. ( Ban, Y; Kawada, Y; Kuriyama, M; Setsuda, O; Shinoda, I; Shinoda, T; Shirai, T; Takeuchi, T; Yamada, S, 1988) |
| "5-Fluorouracil is a well know drug for chemotherapy of various types of cancer." | 1.39 | Development of 99mTc-5-fluorouracil as a potential tumor diagnostic agent. ( Ali, M; Anwar, J; Dar, UK; Hyder, SW; Javed, M; Khan, I; Murad, S, 2013) |
| "Renal cell carcinoma is an uncommon tumor in adults." | 1.33 | Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma. ( Alcaide-García, J; Alés-Díaz, I; Benavides-Orgaz, M; Cobo-Dols, M; Gil-Calle, S; Gutiérrez-Calderón, V; Montesa-Pino, A; Villar-Chamorro, E, 2006) |
| "Columnar-lined or Barrett's esophagus is a premalignant condition." | 1.29 | Is chemotherapy associated with development of Barrett's esophagus? ( Kleibeuker, JH; Peters, FT; Sleijfer, DT; van Imhoff, GW, 1993) |
| "A human testicular cancer serially transplanted in nude mice was repeatedly exposed to CDDP in vivo to obtain hyposensitivity to this drug." | 1.27 | [Chemotherapy of carcinoma of the prostate and testis: experimental study in vivo and in vitro]. ( Hashimura, T; Hida, S; Kanamaru, H; Nishimura, K; Nishio, Y; Oishi, K; Okada, K; Yamauchi, T; Yoshida, O; Yoshiki, T, 1988) |
| "Seven human testicular tumors were transplanted into artificially immunosuppressed mice." | 1.27 | Characteristics and chemotherapeutic sensitivity of a human testicular cancer grown in artificially immunosuppressed mice. ( Bodrogi, I; Eckhardt, S; Kopper, L; Lapis, K; Lapis, P; Sugár, J, 1985) |
| "All 14 patients with breast carcinoma underwent remission and in 6 this was complete." | 1.25 | Seventy-five cases of solid tumours treated by a modified quadruple chemotherapy regime. ( Hanham, IW; Newton, KA; Westbury, G, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (78.72) | 18.7374 |
| 1990's | 3 (6.38) | 18.2507 |
| 2000's | 3 (6.38) | 29.6817 |
| 2010's | 2 (4.26) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Breadner, D | 1 |
| Loree, JM | 1 |
| Cheung, WY | 1 |
| Gipson, M | 1 |
| Lakkunarajah, S | 1 |
| Mulder, KE | 1 |
| Spartlin, JL | 1 |
| Kong, S | 1 |
| Ding, PQ | 1 |
| Gill, S | 1 |
| Welch, SA | 1 |
| Zhang, C | 1 |
| Zhan, Y | 1 |
| Ni, K | 1 |
| Liu, Z | 1 |
| Xin, R | 1 |
| Han, Q | 1 |
| Li, G | 1 |
| Ping, H | 1 |
| Liu, Y | 1 |
| Zhao, X | 1 |
| Wang, W | 1 |
| Yan, S | 1 |
| Sun, J | 1 |
| Zhang, Q | 1 |
| Wang, G | 1 |
| Zhang, Z | 1 |
| Zhang, X | 1 |
| Hu, X | 1 |
| Dar, UK | 1 |
| Khan, I | 1 |
| Javed, M | 1 |
| Ali, M | 1 |
| Hyder, SW | 1 |
| Murad, S | 1 |
| Anwar, J | 1 |
| Deville, JL | 1 |
| Flechon, A | 1 |
| Bruyère, F | 1 |
| Karsenty, G | 1 |
| Guy, L | 1 |
| Bastide, C | 1 |
| DESBERG, D | 1 |
| TANNO, V | 1 |
| SULLIVAN, RD | 1 |
| ZUREK, WZ | 1 |
| BRULE, G | 1 |
| SCHLUMBERGER, JR | 1 |
| GRISCELLI, C | 1 |
| Cobo-Dols, M | 1 |
| Alés-Díaz, I | 1 |
| Villar-Chamorro, E | 1 |
| Gil-Calle, S | 1 |
| Alcaide-García, J | 1 |
| Montesa-Pino, A | 1 |
| Gutiérrez-Calderón, V | 1 |
| Benavides-Orgaz, M | 1 |
| Oechsle, K | 1 |
| Honecker, F | 1 |
| Kollmannsberger, C | 1 |
| Rick, O | 1 |
| Grünwald, V | 1 |
| Mayer, F | 1 |
| Hartmann, JT | 1 |
| Bokemeyer, C | 1 |
| Aldrich, JT | 1 |
| Stevens, LC | 2 |
| Jurga, L | 1 |
| Mrinák, J | 1 |
| Ponist, J | 1 |
| Sefara, P | 1 |
| Berc, A | 1 |
| Goan, SR | 1 |
| Fichtner, I | 1 |
| Just, U | 1 |
| Karawajew, L | 1 |
| Schultze, W | 1 |
| Krause, KP | 1 |
| von Harsdorf, S | 1 |
| von Schilling, C | 1 |
| Herrmann, F | 1 |
| Peters, FT | 1 |
| Sleijfer, DT | 1 |
| van Imhoff, GW | 1 |
| Kleibeuker, JH | 1 |
| Rowinsky, EK | 1 |
| Pan, CC | 1 |
| Chiang, H | 1 |
| Chang, YH | 1 |
| Epstein, JI | 1 |
| Samuels, ML | 3 |
| Holoye, PY | 2 |
| Johnson, DE | 3 |
| Bracken, RB | 1 |
| Ayala, AG | 1 |
| Lanzotti, VJ | 1 |
| Boyle, LE | 1 |
| Smith, TL | 1 |
| Montague, DK | 1 |
| Carter, SK | 1 |
| Wasserman, TH | 1 |
| Livingston, RB | 1 |
| Merrin, CE | 1 |
| Murphy, GP | 1 |
| Kimball, JC | 1 |
| Cangir, A | 1 |
| Reuter, HJ | 1 |
| Baumgartner, G | 1 |
| Geveling, NV | 1 |
| Zhogoleva, IB | 1 |
| Okada, K | 1 |
| Kanamaru, H | 1 |
| Yoshiki, T | 1 |
| Hashimura, T | 1 |
| Nishimura, K | 1 |
| Hida, S | 1 |
| Nishio, Y | 1 |
| Oishi, K | 1 |
| Yoshida, O | 1 |
| Yamauchi, T | 1 |
| Barton, JC | 1 |
| Lapis, P | 1 |
| Kopper, L | 1 |
| Bodrogi, I | 1 |
| Sugár, J | 1 |
| Lapis, K | 1 |
| Eckhardt, S | 1 |
| Kawai, T | 1 |
| Wang, QL | 1 |
| Shinoda, I | 1 |
| Takeuchi, T | 1 |
| Kuriyama, M | 1 |
| Ban, Y | 1 |
| Kawada, Y | 1 |
| Yamada, S | 1 |
| Setsuda, O | 1 |
| Shinoda, T | 1 |
| Shirai, T | 1 |
| Kissel, P | 1 |
| Bessot, M | 1 |
| Duprez, A | 1 |
| Armstrong, JG | 1 |
| Alberto, P | 1 |
| Kühböck, J | 1 |
| Pokorny, D | 1 |
| Steinbach, K | 1 |
| Eggerth, G | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Mount, BM | 3 |
| Thelmo, WL | 1 |
| Husk, M | 2 |
| Ansfield, FJ | 1 |
| Mackman, S | 1 |
| Ramirez, G | 1 |
| Lawton, RL | 1 |
| Gulesserian, HP | 1 |
| Song, J | 1 |
| From, P | 1 |
| Morrissey, WJ | 1 |
| Sams, J | 1 |
| Hanham, IW | 1 |
| Newton, KA | 1 |
| Westbury, G | 1 |
| Mendelson, D | 1 |
| Serpick, AA | 1 |
| Whitmore, WF | 1 |
5 reviews available for fluorouracil and Testicular Neoplasms
| Article | Year |
|---|---|
[Chemotherapy in male external genital organs (testicular and penile cancer)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Chemotherapy, Adjuvant; Cisp | 2013 |
Paclitaxel pharmacology and other tumor types.
Topics: Alkylating Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols | 1997 |
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinom | 1976 |
[Primary carcinoid tumor of the testis: a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Combined Modality Therapy; C | 1988 |
Newer concepts in chemotherapy of cancer.
Topics: Breast Neoplasms; Colonic Neoplasms; Dysgerminoma; Female; Fluorouracil; Humans; Injections, Intra-A | 1972 |
1 trial available for fluorouracil and Testicular Neoplasms
| Article | Year |
|---|---|
An open-label, multicenter phase II trial of capecitabine in patients with cisplatin-refractory or relapsed germ cell tumors.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blood Cell Count; Capecitabine; Cispl | 2007 |
41 other studies available for fluorouracil and Testicular Neoplasms
| Article | Year |
|---|---|
The influence of adjuvant chemotherapy dose intensity on overall survival in resected colon cancer: a multicentered retrospective analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Canada; Capecitabine; Chemotherapy, Adjuvant; Coloni | 2022 |
Effects of deficient mismatch repair on the prognosis of patients with stage II and stage III colon cancer during different postoperative periods.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; DNA | 2022 |
Development of 99mTc-5-fluorouracil as a potential tumor diagnostic agent.
Topics: Animals; Drug Stability; Fluorouracil; Hydrophobic and Hydrophilic Interactions; Isotope Labeling; K | 2013 |
ADENOCARCINOMA OF THE RETE TESTIS.
Topics: Adenocarcinoma; Fluorouracil; Geriatrics; Humans; Male; Radiotherapy; Rete Testis; Surgical Procedur | 1964 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf | 1964 |
N-ISOPROPYL-ALPHA-(2-METHYLHYDRAZINO)-P-TOLUAMIDE, HYDROCHLORIDE (NSC-77213) IN TREATMENT OF SOLID TUMORS.
Topics: Antineoplastic Agents; Breast Neoplasms; Drug Therapy; Fluorouracil; Humans; Injections, Intra-Arter | 1965 |
Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma.
Topics: Adenocarcinoma, Clear Cell; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carc | 2006 |
Effect of 5-fluorouracil on early teratomas in mice.
Topics: Animals; Fluorouracil; Injections; Male; Mice; Neoplasm Transplantation; Teratoma; Testicular Neopla | 1967 |
Non-invasive methods for detection of cardiomyopathy in the course of antineoplastic treatment.
Topics: Antineoplastic Agents; Breast Neoplasms; Cardiomyopathies; Doxorubicin; Drug Therapy, Combination; F | 1982 |
The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis.
Topics: Adult; Animals; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone | 1995 |
Is chemotherapy associated with development of Barrett's esophagus?
Topics: Adult; Antineoplastic Agents; Barrett Esophagus; Breast Neoplasms; Cisplatin; Drug Therapy, Combinat | 1993 |
Tubulocystic clear cell adenocarcinoma arising within the prostate.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Fluor | 2000 |
Bleomycin combination chemotherapy in the management of testicular neoplasia.
Topics: Abdominal Neoplasms; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fl | 1975 |
Retroperitoneal lymphadenectomy as adjunctive therapy in selected cases of advanced testicular carcinoma.
Topics: Adolescent; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lym | 1976 |
Combination chemotherapy in germinal cell tumors.
Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Choriocarcinoma; Cyclophosphamide; Drug Therapy | 1976 |
Retroperitoneal germ cell tumors with no apparent testicular involvement.
Topics: Adult; Biopsy; Cyclophosphamide; Dysgerminoma; Fluorouracil; Follow-Up Studies; Humans; Male; Methot | 1975 |
The chemotherapy of urologic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Co | 1975 |
Chemotherapy of urogenital cancer.
Topics: Adenocarcinoma; Adult; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Hum | 1976 |
Occurrence of testicular metastasis in a child with bilateral retinoblastoma.
Topics: Antineoplastic Agents; Child, Preschool; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, | 1979 |
[Multifactorial immunological treatment of cancer in urology].
Topics: Adenocarcinoma; Adult; Aged; Antibody Formation; Cobalt Radioisotopes; Female; Fluorouracil; Humans; | 1976 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
[Experience in the use of T-activin in patients with malignant testicular tumors and patients with kidney cancer].
Topics: Adjuvants, Immunologic; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisp | 1986 |
[Chemotherapy of carcinoma of the prostate and testis: experimental study in vivo and in vitro].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Line | 1988 |
Tumor lysis syndrome in nonhematopoietic neoplasms.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Carcinoma, Intraductal, | 1989 |
Characteristics and chemotherapeutic sensitivity of a human testicular cancer grown in artificially immunosuppressed mice.
Topics: Adult; alpha-Fetoproteins; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |
[Preoperative chemotherapy of testicular cancer and Wilm's tumor].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; | 1985 |
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neop | 1989 |
[Loco-regional and sequential chemotherapy of advanced cancer].
Topics: Adult; Carcinoma; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Dysgerminoma; | 1968 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Comments on the treatment of solid tumors with 5-fluorouracil].
Topics: Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carcinoma, Hepatocellular; Female; Fluorouracil; | 1969 |
[Polychemotherapy of malignant tumors and hemoblastoses].
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinom | 1968 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
A re-examination of the renal blastema graft model for Wilms tumor production.
Topics: Animals; Autopsy; Cell Differentiation; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Drug | 1974 |
ICRF-159 in treatment of germinal testicular tumor in animals.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Dogs; Drug T | 1974 |
Advanced cancer: New concepts of medical therapy.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Choriocarcinoma; Colonic Neopl | 1973 |
Complete regression of metastases following chemotherapy.
Topics: Aged; Cecal Neoplasms; Colectomy; Fluorouracil; Humans; Injections, Intravenous; Lung Neoplasms; Lym | 1971 |
Circulating cancer cells: pre- and post-chemotherapy observations.
Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Female; Filtration; Fluorouracil; Humans; Male; | 1971 |
Seventy-five cases of solid tumours treated by a modified quadruple chemotherapy regime.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Flu | 1971 |
Combination chemotherapy of testicular tumors.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Teratoma; | 1970 |
The effect of chemotherapy on germinal testicular tumors in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluo | 1970 |
[Therapy of testicular tumors and prostatic carcinoma].
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cobalt Isotopes; Estrogens; Fluorouracil; Humans; Male | 1971 |