fluorouracil has been researched along with Testicular Diseases in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Testicular Diseases: Pathological processes of the TESTIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil is one of the most commonly used anticancer drugs for the treatment of various types of cancer but has potential adverse effects such as intestinal mucositis, renal, hepatic, and reproductive organ toxicity." | 7.83 | Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study. ( Al-Asmari, AK; Al-Shahrani, HM; Al-Zahrani, AM; Ali Al Amri, M; Khan, AQ, 2016) |
| "5-Fluorouracil is one of the most commonly used anticancer drugs for the treatment of various types of cancer but has potential adverse effects such as intestinal mucositis, renal, hepatic, and reproductive organ toxicity." | 3.83 | Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study. ( Al-Asmari, AK; Al-Shahrani, HM; Al-Zahrani, AM; Ali Al Amri, M; Khan, AQ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Asmari, AK | 1 |
| Al-Zahrani, AM | 1 |
| Khan, AQ | 1 |
| Al-Shahrani, HM | 1 |
| Ali Al Amri, M | 1 |
1 other study available for fluorouracil and Testicular Diseases
| Article | Year |
|---|---|
Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study.
Topics: Animals; Dose-Response Relationship, Drug; Fluorouracil; Intestinal Diseases; Intestines; Kidney; Li | 2016 |