Page last updated: 2024-10-27

fluorouracil and Testicular Diseases

fluorouracil has been researched along with Testicular Diseases in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Testicular Diseases: Pathological processes of the TESTIS.

Research Excerpts

ExcerptRelevanceReference
"5-Fluorouracil is one of the most commonly used anticancer drugs for the treatment of various types of cancer but has potential adverse effects such as intestinal mucositis, renal, hepatic, and reproductive organ toxicity."7.83Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study. ( Al-Asmari, AK; Al-Shahrani, HM; Al-Zahrani, AM; Ali Al Amri, M; Khan, AQ, 2016)
"5-Fluorouracil is one of the most commonly used anticancer drugs for the treatment of various types of cancer but has potential adverse effects such as intestinal mucositis, renal, hepatic, and reproductive organ toxicity."3.83Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study. ( Al-Asmari, AK; Al-Shahrani, HM; Al-Zahrani, AM; Ali Al Amri, M; Khan, AQ, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Asmari, AK1
Al-Zahrani, AM1
Khan, AQ1
Al-Shahrani, HM1
Ali Al Amri, M1

Other Studies

1 other study available for fluorouracil and Testicular Diseases

ArticleYear
Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study.
    Human & experimental toxicology, 2016, Volume: 35, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Fluorouracil; Intestinal Diseases; Intestines; Kidney; Li

2016