fluorouracil has been researched along with Teratoma in 32 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
| Excerpt | Relevance | Reference |
|---|---|---|
| " HeLa cells and a murine teratoma cell line were suspended in solutions of tonicities 154, 308, and 616 mosM, each containing the same quantity of 5-fluorouracil, and uptake of the drug was measured at different intervals over 30 min." | 3.68 | Effect of osmotic pressure on uptake of chemotherapeutic agents by carcinoma cells. ( Buys, SS; Jensen, EM; Kablitz, C; Novak, JM; Stephen, RL, 1990) |
| "Squamous cell carcinoma is the most common malignant change." | 2.78 | Characteristics and treatment outcomes of patients with malignant transformation arising from mature cystic teratoma of the ovary: experience at a single institution. ( Khemapech, N; Oranratanaphan, S, 2013) |
| "The most common malignancy is squamous cell carcinoma, which consists of about 75% of malignant transformations." | 1.35 | Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report. ( Azadbakht, F; Emami-Aleagha, M; Hajarizadeh, B; Keshvari, A; Rosai, J; Sedighi, S; Shariat-Torbaghan, S, 2009) |
| "Seven human testicular tumors were transplanted into artificially immunosuppressed mice." | 1.27 | Characteristics and chemotherapeutic sensitivity of a human testicular cancer grown in artificially immunosuppressed mice. ( Bodrogi, I; Eckhardt, S; Kopper, L; Lapis, K; Lapis, P; Sugár, J, 1985) |
| " Both dosage and releasing time can be adjusted." | 1.27 | [Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites]. ( Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M, 1986) |
| " Even so, HCFU should be dosed when needed in spite of this risk." | 1.27 | [A case of leukoencephalopathy caused by HCFU]. ( Abe, S; Kamata, H; Kisida, S; Miyagawa, N; Murakami, A; Nagano, H; Ueda, K; Yasui, H, 1988) |
| "A series of 25 patients with malignant teratoma of the ovary is presented." | 1.26 | Malignant teratoma of the ovary: prognostic factors and treatment. ( Curry, SL; Gallagher, HS; Smith, JP, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (87.50) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oranratanaphan, S | 1 |
| Khemapech, N | 1 |
| Li, X | 1 |
| Xu, JX | 1 |
| Jia, XS | 1 |
| Li, WY | 1 |
| Han, YC | 1 |
| Wang, EH | 1 |
| Li, F | 1 |
| Shariat-Torbaghan, S | 1 |
| Emami-Aleagha, M | 1 |
| Sedighi, S | 1 |
| Azadbakht, F | 1 |
| Keshvari, A | 1 |
| Hajarizadeh, B | 1 |
| Rosai, J | 1 |
| DESBERG, D | 1 |
| TANNO, V | 1 |
| Thompson, JP | 1 |
| Dockerty, MB | 1 |
| Symmonds, RE | 2 |
| Hayles, AB | 1 |
| Aldrich, JT | 1 |
| Stevens, LC | 2 |
| Samuels, ML | 3 |
| Holoye, PY | 2 |
| Johnson, DE | 3 |
| Bracken, RB | 1 |
| Ayala, AG | 1 |
| Lanzotti, VJ | 1 |
| Boyle, LE | 1 |
| Smith, TL | 1 |
| Montague, DK | 1 |
| Curry, SL | 1 |
| Smith, JP | 3 |
| Gallagher, HS | 1 |
| Forney, JP | 1 |
| Di Saia, PJ | 1 |
| Morrow, CP | 1 |
| Rutledge, F | 2 |
| Stephen, RL | 1 |
| Novak, JM | 1 |
| Jensen, EM | 1 |
| Kablitz, C | 1 |
| Buys, SS | 1 |
| Ihara, T | 1 |
| Hisamatsu, K | 1 |
| Okamoto, E | 1 |
| Suemitsu, H | 1 |
| Yamada, M | 1 |
| Matsuda, M | 1 |
| Nanba, K | 1 |
| Kirimoto, K | 1 |
| Lapis, P | 1 |
| Kopper, L | 1 |
| Bodrogi, I | 1 |
| Sugár, J | 1 |
| Lapis, K | 1 |
| Eckhardt, S | 1 |
| Sawada, M | 2 |
| Kubo, O | 1 |
| Himuro, H | 1 |
| Inoue, N | 1 |
| Tajika, Y | 1 |
| Tajika, T | 1 |
| Tohyama, T | 1 |
| Sakairi, M | 1 |
| Yoshida, M | 1 |
| Kaetsu, I | 1 |
| Kitamura, K | 1 |
| Kamata, H | 1 |
| Murakami, A | 1 |
| Miyagawa, N | 1 |
| Yasui, H | 1 |
| Nagano, H | 1 |
| Abe, S | 1 |
| Ueda, K | 1 |
| Kisida, S | 1 |
| Ozaki, M | 1 |
| Hongo, J | 1 |
| Hirota, Y | 1 |
| Inagaki, M | 1 |
| Sutow, WW | 1 |
| Alberto, P | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Malkasian, GD | 2 |
| Webb, MJ | 1 |
| Jorgensen, EO | 1 |
| Mount, BM | 2 |
| Husk, M | 1 |
| Song, J | 1 |
| From, P | 1 |
| Morrissey, WJ | 1 |
| Sams, J | 1 |
| Meriwether, WD | 1 |
| Ramsey, HE | 1 |
| Ward, SP | 1 |
| Mendelson, D | 1 |
| Serpick, AA | 1 |
| Whitmore, WF | 1 |
| Schwartz, SA | 1 |
| Perry, S | 1 |
2 trials available for fluorouracil and Teratoma
| Article | Year |
|---|---|
Characteristics and treatment outcomes of patients with malignant transformation arising from mature cystic teratoma of the ovary: experience at a single institution.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 2013 |
Advances in chemotherapy for gynecologic cancer.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug | 1975 |
30 other studies available for fluorouracil and Teratoma
| Article | Year |
|---|---|
Dormancy activation mechanism of tracheal stem cells.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Bronchi; Cell Differentiation; Cell Proliferati | 2016 |
Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Che | 2009 |
ADENOCARCINOMA OF THE RETE TESTIS.
Topics: Adenocarcinoma; Fluorouracil; Geriatrics; Humans; Male; Radiotherapy; Rete Testis; Surgical Procedur | 1964 |
Ovarian and parovarian tumors in infants and children.
Topics: Adenocarcinoma; Adolescent; Child; Child, Preschool; Dysgerminoma; Female; Fluorouracil; Histocytoch | 1967 |
Effect of 5-fluorouracil on early teratomas in mice.
Topics: Animals; Fluorouracil; Injections; Male; Mice; Neoplasm Transplantation; Teratoma; Testicular Neopla | 1967 |
Bleomycin combination chemotherapy in the management of testicular neoplasia.
Topics: Abdominal Neoplasms; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fl | 1975 |
Retroperitoneal lymphadenectomy as adjunctive therapy in selected cases of advanced testicular carcinoma.
Topics: Adolescent; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lym | 1976 |
Combination chemotherapy in germinal cell tumors.
Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Choriocarcinoma; Cyclophosphamide; Drug Therapy | 1976 |
Retroperitoneal germ cell tumors with no apparent testicular involvement.
Topics: Adult; Biopsy; Cyclophosphamide; Dysgerminoma; Fluorouracil; Follow-Up Studies; Humans; Male; Methot | 1975 |
Malignant teratoma of the ovary: prognostic factors and treatment.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Drug Therapy, Combi | 1978 |
Endodermal sinus tumor: a report of two sustained remissions treated postoperatively with a combination of actinomycin D, 5-fluorouracil, and cyclophosphamide.
Topics: Adolescent; Adult; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; | 1975 |
Effect of osmotic pressure on uptake of chemotherapeutic agents by carcinoma cells.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Dextrans; Doxorubicin; Female; Fluorouracil; He | 1990 |
[Transformation of ovarian yolk sac tumor to immature teratoma following chemotherapy].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; | 1985 |
Characteristics and chemotherapeutic sensitivity of a human testicular cancer grown in artificially immunosuppressed mice.
Topics: Adult; alpha-Fetoproteins; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |
[Experimental chemotherapy of ovarian cancers heterotransplanted in nude mice].
Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto | 1985 |
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysge | 1986 |
[A case of leukoencephalopathy caused by HCFU].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; B | 1988 |
[Effect of post operative maintenance chemotherapy against ovarian cancer].
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Mice; Mice, | 1987 |
Malignant gynecologic tumors in children: current approaches to treatment.
Topics: Age Factors; Child; Child, Preschool; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; | 1973 |
[Comments on the treatment of solid tumors with 5-fluorouracil].
Topics: Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carcinoma, Hepatocellular; Female; Fluorouracil; | 1969 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
Observations on chemotherapy of granulosa cell carcinomas and malignant ovarian teratomas.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Cyclophosphamide; Dactinomycin; Fallopi | 1974 |
ICRF-159 in treatment of germinal testicular tumor in animals.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Dogs; Drug T | 1974 |
Advanced cancer: New concepts of medical therapy.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Choriocarcinoma; Colonic Neopl | 1973 |
Circulating cancer cells: pre- and post-chemotherapy observations.
Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Female; Filtration; Fluorouracil; Humans; Male; | 1971 |
Embryonal cell carcinoma of the ovary. Report of a case.
Topics: Abdominal Neoplasms; Adolescent; Age Factors; Black People; Cyclophosphamide; Drug Therapy, Combinat | 1971 |
Combination chemotherapy of testicular tumors.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Teratoma; | 1970 |
The effect of chemotherapy on germinal testicular tumors in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluo | 1970 |
Solid malignant ovarian teratoma: case of an 8 year survival.
Topics: Adult; Castration; Colon; Female; Fluorouracil; Follow-Up Studies; Humans; Hysterectomy; Ileum; Inje | 1971 |
Patient protection in cancer chemotherapy.
Topics: Adult; Anti-Bacterial Agents; Culture Media; Cyclophosphamide; Fluorouracil; Germ-Free Life; Humans; | 1966 |