fluorouracil has been researched along with Takotsubo Cardiomyopathy in 12 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Takotsubo Cardiomyopathy: A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of acute heart failure due to Takotsubo cardiomyopathy induced by 5-fluorouracil is described." | 7.75 | A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma. ( Hata, N; Kobayashi, N; Mizuno, K; Shinada, T; Shirakabe, A; Yokoyama, S, 2009) |
| "A 17 year-old male with metastatic pancreatic adenocarcinoma, under chemotherapy containing 5-fluorouracil, presented severe left ventricular dysfunction requiring mechanical ventilation and inotropes administration." | 3.83 | Transient global ventricular dysfunction in an adolescent affected by pancreatic adenocarcinoma. ( Chinali, M; De Pasquale, MD; De Sio, L; Giordano, U; Grimaldi, C; Mastronuzzi, A; Serra, A, 2016) |
| " She underwent recent chemotherapy with fluorouracil for metastatic colorectal cancer." | 3.75 | 5 flourouracil-induced apical ballooning syndrome: a case report. ( Dentali, F; Gianni, M; Lonn, E, 2009) |
| "A case of acute heart failure due to Takotsubo cardiomyopathy induced by 5-fluorouracil is described." | 3.75 | A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma. ( Hata, N; Kobayashi, N; Mizuno, K; Shinada, T; Shirakabe, A; Yokoyama, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Valero, M | 1 |
| Courand, PY | 1 |
| Gilbert, T | 1 |
| Bonnin, N | 1 |
| Bonnefoy, M | 1 |
| Lantelme, P | 1 |
| Falandry, C | 1 |
| Coen, M | 1 |
| Rigamonti, F | 1 |
| Roth, A | 1 |
| Koessler, T | 1 |
| Smith, SA | 1 |
| Auseon, AJ | 1 |
| Klag, T | 1 |
| Cantara, G | 1 |
| Ong, P | 1 |
| Kaufmann, M | 1 |
| Sechtem, U | 1 |
| Athanasiadis, A | 1 |
| Knott, K | 1 |
| Starling, N | 1 |
| Rasheed, S | 1 |
| Foran, J | 1 |
| Cafferkey, C | 1 |
| Rosen, S | 1 |
| Nicholson, A | 1 |
| Baksi, J | 1 |
| Lyon, A | 1 |
| De Pasquale, MD | 1 |
| Mastronuzzi, A | 1 |
| De Sio, L | 1 |
| Serra, A | 1 |
| Grimaldi, C | 1 |
| Chinali, M | 1 |
| Giordano, U | 1 |
| Kim, L | 1 |
| Karas, M | 1 |
| Wong, SC | 1 |
| Gianni, M | 1 |
| Dentali, F | 1 |
| Lonn, E | 1 |
| Kobayashi, N | 1 |
| Hata, N | 1 |
| Yokoyama, S | 1 |
| Shinada, T | 1 |
| Shirakabe, A | 1 |
| Mizuno, K | 1 |
| Basselin, C | 1 |
| Fontanges, T | 1 |
| Descotes, J | 1 |
| Chevalier, P | 1 |
| Bui-Xuan, B | 1 |
| Feinard, G | 1 |
| Timour, Q | 1 |
| Grunwald, MR | 1 |
| Howie, L | 1 |
| Diaz, LA | 1 |
| Ozturk, MA | 1 |
| Ozveren, O | 1 |
| Cinar, V | 1 |
| Erdik, B | 1 |
| Oyan, B | 1 |
3 reviews available for fluorouracil and Takotsubo Cardiomyopathy
| Article | Year |
|---|---|
Chemotherapy-induced takotsubo cardiomyopathy.
Topics: Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Agents; Echo | 2013 |
Takotsubo cardiomyopathy and Fluorouracil: case report and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Mid | 2012 |
Takotsubo syndrome: an underdiagnosed complication of 5-fluorouracil mimicking acute myocardial infarction.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemoth | 2013 |
9 other studies available for fluorouracil and Takotsubo Cardiomyopathy
| Article | Year |
|---|---|
Geriatric oncologists should be aware of cardio-oncology: Impact of age and gender on 5-FU-mediated TakoTsubo cardiomyopathy.
Topics: Aged; Fluorouracil; Humans; Medical Oncology; Neoplasms; Oncologists; Takotsubo Cardiomyopathy | 2020 |
Chemotherapy-induced Takotsubo cardiomyopathy, a case report and review of the literature.
Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurr | 2017 |
Epicardial coronary artery spasm as cause of capecitabine-induced tako tsubo cardiomyopathy.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Coronary Angiogr | 2014 |
A case of Takotsubo syndrome following 5-fluorouracil chemotherapy.
Topics: Cardiotoxicity; Electrocardiography; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle | 2014 |
Transient global ventricular dysfunction in an adolescent affected by pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Adolescent; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Male; Pancreatic | 2016 |
Chemotherapy-induced takotsubo cardiomyopathy.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; An | 2008 |
5 flourouracil-induced apical ballooning syndrome: a case report.
Topics: Aged; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Coronary Disease; Female; Fluorouracil; | 2009 |
A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Female; Fluorouracil; Heart Failure; Humans; Middle | 2009 |
5-Fluorouracil-induced Tako-Tsubo-like syndrome.
Topics: Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Humans; Male; Middle Aged; Takotsu | 2011 |