fluorouracil has been researched along with Superior Vena Cava Obstruction in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These patients can also be affected by superior vena cava syndrome causing dyspnea followed by trunk or extremity swelling." | 1.35 | Treatment of superior vena cava (SVC) syndrome and inferior vena cava (IVC) thrombosis in a patient with colorectal cancer: combination of SVC stenting and IVC filter placement to palliate symptoms and pave the way for port implantation. ( Kickuth, R; Sauter, A; Schmidt, F; Triller, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giuliani, J | 1 |
| Martelli, S | 1 |
| Piacentini, P | 1 |
| Bonetti, A | 1 |
| Sauter, A | 1 |
| Triller, J | 1 |
| Schmidt, F | 1 |
| Kickuth, R | 1 |
| Manheimer, F | 1 |
| Aranda, CP | 1 |
| Smith, RL | 1 |
| Kerr, HD | 1 |
4 other studies available for fluorouracil and Superior Vena Cava Obstruction
| Article | Year |
|---|---|
Thromboembolic disease in advanced colorectal cancer treated with chemotherapy and bevacizumab: a case of real "pan-thrombosis".
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro | 2015 |
Treatment of superior vena cava (SVC) syndrome and inferior vena cava (IVC) thrombosis in a patient with colorectal cancer: combination of SVC stenting and IVC filter placement to palliate symptoms and pave the way for port implantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catheterization, Peripheral; Colorectal Neoplasms; C | 2008 |
Necrotizing pneumonitis caused by 5-fluorouracil infusion. A complication of a Hickman catheter.
Topics: Aged; Brachiocephalic Veins; Catheters, Indwelling; Fluorouracil; Foreign-Body Migration; Humans; In | 1992 |
Superior vena cava syndrome associated with a Hickman catheter.
Topics: Catheterization, Central Venous; Catheters, Indwelling; Colonic Neoplasms; Fluorouracil; Humans; Inf | 1990 |