Page last updated: 2024-10-27

fluorouracil and Spinal Fractures

fluorouracil has been researched along with Spinal Fractures in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Spinal Fractures: Broken bones in the vertebral column.

Research Excerpts

ExcerptRelevanceReference
"Hyporexia/anorexia is a relevant clinical problem affecting the quality of life of many cancer patients."1.37Steroids, cancer and vertebral fractures: a dreaded combination. ( Uña Cidón, E, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaczmarek, K1
Wiącek, MP1
Sulewski, A1
Kubaszewski, Ł1
Kaczmarczyk, J1
Nowakowski, A1
Uña Cidón, E1

Other Studies

2 other studies available for fluorouracil and Spinal Fractures

ArticleYear
Failure and success in the treatment of breast carcinoma in men: a case report.
    Polish orthopedics and traumatology, 2014, Jan-03, Volume: 79

    Topics: Antineoplastic Combined Chemotherapy Protocols; Back Pain; Breast Neoplasms, Male; Carcinoma, Ductal

2014
Steroids, cancer and vertebral fractures: a dreaded combination.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:3

    Topics: Adrenal Cortex Hormones; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Capecitabin

2011