fluorouracil has been researched along with Spinal Cord Diseases in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Spinal Cord Diseases: Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article describes a woman with metastatic upper gastrointestinal cancer who developed thoracic myelopathy unexpectedly after standard dosage and fractionation radiotherapy." | 5.33 | Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine. ( Barstis, JL; Black, AC, 2005) |
| "This article describes a woman with metastatic upper gastrointestinal cancer who developed thoracic myelopathy unexpectedly after standard dosage and fractionation radiotherapy." | 1.33 | Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine. ( Barstis, JL; Black, AC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paralta Branco, F | 1 |
| Brito, CB | 1 |
| Luz, G | 1 |
| Teixeira, JA | 1 |
| Chan, L | 1 |
| Yeo, W | 1 |
| Leung, SF | 1 |
| Griffith, J | 1 |
| Ng, EK | 1 |
| Chan, AT | 1 |
| Barstis, JL | 1 |
| Black, AC | 1 |
| Sun, Y | 1 |
| Wang, LX | 1 |
| Wang, L | 1 |
| Sun, SX | 1 |
| Cao, XJ | 1 |
| Wang, P | 1 |
| Feng, L | 1 |
4 other studies available for fluorouracil and Spinal Cord Diseases
| Article | Year |
|---|---|
Central venous catheter misplaced in the epidural space.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Catheterization, Central Venous; Centra | 2019 |
Delayed radiation myelopathy after concurrent chemoradiation for hypopharyngeal-esophageal carcinoma.
Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Degluti | 2005 |
Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi | 2005 |
A comparison of the effectiveness of mitomycin C and 5-fluorouracil in the prevention of peridural adhesion after laminectomy.
Topics: Animals; Antimetabolites, Antineoplastic; Dura Mater; Fluorouracil; Laminectomy; Lumbar Vertebrae; M | 2007 |