Page last updated: 2024-10-27

fluorouracil and Spasm

fluorouracil has been researched along with Spasm in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"Coronary spasm is a recognized complication of fluorouracil (FU) chemotherapy."8.84Fluorouracil-induced hepatic artery spasm preventing yttrium-90 microsphere administration. ( Patterson, K; Pittman, K; Price, TJ; Townsend, A, 2008)
"Coronary artery spasm has been postulated to be involved in the mechanism of this incident Patients may present with angina, myocardial infarction, arrhythmias and/or even sudden death."5.31A case of coronary spasm induced by 5-fluorouracil. ( Celik, S; Gorgulu, S; Tezel, T, 2002)
"Coronary spasm is a recognized complication of fluorouracil (FU) chemotherapy."4.84Fluorouracil-induced hepatic artery spasm preventing yttrium-90 microsphere administration. ( Patterson, K; Pittman, K; Price, TJ; Townsend, A, 2008)
"Coronary artery spasm has been postulated to be involved in the mechanism of this incident Patients may present with angina, myocardial infarction, arrhythmias and/or even sudden death."1.31A case of coronary spasm induced by 5-fluorouracil. ( Celik, S; Gorgulu, S; Tezel, T, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Townsend, A1
Price, TJ1
Patterson, K1
Pittman, K1
Lucchetta, M1
Lonardi, S1
Bergamo, F1
Alberti, P1
Velasco, R1
Argyriou, AA1
Briani, C1
Bruna, J1
Cazzaniga, M1
Cortinovis, D1
Cavaletti, G1
Kalofonos, HP1
Gorgulu, S1
Celik, S1
Tezel, T1

Reviews

1 review available for fluorouracil and Spasm

ArticleYear
Fluorouracil-induced hepatic artery spasm preventing yttrium-90 microsphere administration.
    Clinical nuclear medicine, 2008, Volume: 33, Issue:8

    Topics: Antimetabolites, Antineoplastic; Capsules; Diagnostic Errors; Female; Fluorouracil; Hepatic Artery;

2008

Other Studies

2 other studies available for fluorouracil and Spasm

ArticleYear
Incidence of atypical acute nerve hyperexcitability symptoms in oxaliplatin-treated patients with colorectal cancer.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6

    Topics: Acute Disease; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecita

2012
A case of coronary spasm induced by 5-fluorouracil.
    Acta cardiologica, 2002, Volume: 57, Issue:5

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Chest Pain; Colonic Neoplasms; Coronary Angiography;

2002