Page last updated: 2024-10-27

fluorouracil and Somatostatinoma

fluorouracil has been researched along with Somatostatinoma in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Somatostatinoma: A SOMATOSTATIN-secreting tumor derived from the pancreatic delta cells (SOMATOSTATIN-SECRETING CELLS). It is also found in the INTESTINE. Somatostatinomas are associated with DIABETES MELLITUS; CHOLELITHIASIS; STEATORRHEA; and HYPOCHLORHYDRIA. The majority of somatostatinomas have the potential for METASTASIS.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brentjens, R1
Saltz, L1

Reviews

1 review available for fluorouracil and Somatostatinoma

ArticleYear
Islet cell tumors of the pancreas: the medical oncologist's perspective.
    The Surgical clinics of North America, 2001, Volume: 81, Issue:3

    Topics: Adenoma, Islet Cell; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Ag

2001