Page last updated: 2024-10-27

fluorouracil and Soft Tissue Neoplasms

fluorouracil has been researched along with Soft Tissue Neoplasms in 28 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.

Research Excerpts

ExcerptRelevanceReference
"PURPOSE To evaluate trastuzumab (H) and docetaxel (T) with or without capecitabine (X) as first-line combination therapy for human epidermal growth factor receptor 2 (HER2) -positive advanced breast cancer."9.14Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer. ( Barton, C; Button, P; de Fátima Dias Gaui, M; Hersberger, V; Jassem, J; Morales-Vasquez, F; Pivot, X; Reyes, DO; Torres, AA; Wardley, AM; Zetina, LM, 2010)
"This study was conducted to determine, in patients with advanced-stage breast cancer, the maximum tolerated dose (MTD) of capecitabine administered orally for 7 days followed by a 7-day rest (7/7), a schedule based on a mathematical method for the optimization of anticancer drug scheduling."9.13Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer. ( Dugan, U; Edwards, C; Feigin, K; Hudis, C; Norton, L; Patil, S; Tan, KL; Theodoulou, M; Traina, TA, 2008)
"To assess the activity of paclitaxel in combination with 5-fluorouracil (5-FU) and leucovorin in breast cancer, a phase II trial was conducted in women with metastatic disease."9.09Paclitaxel, 5-fluorouracil, and leucovorin (TFL) in the treatment of metastatic breast cancer. ( Cohen, A; Hande, KR; Johnson, DH; Meshad, M; Nicholson, BP; Paul, DM; Shyr, Y, 2000)
"Because leucovorin increases the antitumor activity of 5-fluorouracil (5-FU) in multiple tumor model systems, we performed a clinical trial to evaluate this combination in women who had received one or no prior chemotherapy regimens for metastatic breast cancer."9.075-Fluorouracil plus leucovorin in women with metastatic breast cancer. A phase II study. ( Allegra, CJ; Buckner, JC; Edmonson, JH; Ingle, JN; Loprinzi, CL; Schaid, DJ, 1991)
" 5-Fluorouracil, and prednisone (CFP) in patients with advanced breast cancer."9.07A randomized trial of cyclophosphamide, doxorubicin, and prednisone versus cyclophosphamide, 5-fluorouracil, and prednisone in patients with metastatic breast cancer. ( Ahmann, DL; Bisel, HF; Buckner, JC; Ingle, JN; Long, HJ; Rubin, J; Schaid, DJ; Schutt, AJ, 1991)
"Celecoxib was never discontinued for toxicity."6.73Impact of celecoxib on capecitabine tolerability and activity in pretreated metastatic breast cancer: results of a phase II study with biomarker evaluation. ( Carlini, P; Cognetti, F; Fabi, A; Ferretti, G; Gelibter, A; Melucci, E; Metro, G; Milella, M; Mottolese, M; Papaldo, P; Russillo, M; Sperduti, I; Tomao, S, 2008)
"Capecitabine is an orally administered precursor of 5'-deoxy-5-fluorouridine that was rationally designed to generate 5-fluorouracil (5-FU) preferentially in tumor tissue."6.73Safety profile and activity of lower capecitabine dose in patients with metastatic breast cancer. ( Alessandroni, P; Baldelli, AM; Casadei, V; Catalano, G; Catalano, V; Ceccolini, M; Fedeli, A; Fedeli, SL; Giordani, P; Rossi, D, 2007)
"Metastatic breast cancer remains an incurable disease and the median overall survival has not significantly improved over the past two decades."6.69Is salvage chemotherapy for metastatic breast cancer always effective and well tolerated? A phase II randomized trial of vinorelbine versus 5-fluorouracil plus leucovorin versus combination of mitoxantrone, 5-fluorouracil plus leucovorin. ( Comandini, D; Fusco, V; Merlini, L; Naso, C; Palumbo, R; Porcile, G; Pronzato, P; Repetto, L; Rosso, R; Simoni, C; Venturino, A, 2000)
"PURPOSE To evaluate trastuzumab (H) and docetaxel (T) with or without capecitabine (X) as first-line combination therapy for human epidermal growth factor receptor 2 (HER2) -positive advanced breast cancer."5.14Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer. ( Barton, C; Button, P; de Fátima Dias Gaui, M; Hersberger, V; Jassem, J; Morales-Vasquez, F; Pivot, X; Reyes, DO; Torres, AA; Wardley, AM; Zetina, LM, 2010)
"This study was conducted to determine, in patients with advanced-stage breast cancer, the maximum tolerated dose (MTD) of capecitabine administered orally for 7 days followed by a 7-day rest (7/7), a schedule based on a mathematical method for the optimization of anticancer drug scheduling."5.13Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer. ( Dugan, U; Edwards, C; Feigin, K; Hudis, C; Norton, L; Patil, S; Tan, KL; Theodoulou, M; Traina, TA, 2008)
"To assess the activity of paclitaxel in combination with 5-fluorouracil (5-FU) and leucovorin in breast cancer, a phase II trial was conducted in women with metastatic disease."5.09Paclitaxel, 5-fluorouracil, and leucovorin (TFL) in the treatment of metastatic breast cancer. ( Cohen, A; Hande, KR; Johnson, DH; Meshad, M; Nicholson, BP; Paul, DM; Shyr, Y, 2000)
"The relationship between the response to chemotherapy with cyclophosphamide, epirubicin and fluorouracil as well as the time to progression of metastasised breast cancer and DNA ploidy and S-phase fraction (SPF) of primary tumours was examined using paraffin-embedded tumour tissue from 81 patients."5.08Do DNA ploidy and S-phase fraction in primary tumour predict the response to chemotherapy in metastatic breast cancer? ( Blomqvist, C; Franssila, K; Hietanen, P; Niskanen, E; Nordling, S; Wasenius, VM, 1995)
"Because leucovorin increases the antitumor activity of 5-fluorouracil (5-FU) in multiple tumor model systems, we performed a clinical trial to evaluate this combination in women who had received one or no prior chemotherapy regimens for metastatic breast cancer."5.075-Fluorouracil plus leucovorin in women with metastatic breast cancer. A phase II study. ( Allegra, CJ; Buckner, JC; Edmonson, JH; Ingle, JN; Loprinzi, CL; Schaid, DJ, 1991)
" 5-Fluorouracil, and prednisone (CFP) in patients with advanced breast cancer."5.07A randomized trial of cyclophosphamide, doxorubicin, and prednisone versus cyclophosphamide, 5-fluorouracil, and prednisone in patients with metastatic breast cancer. ( Ahmann, DL; Bisel, HF; Buckner, JC; Ingle, JN; Long, HJ; Rubin, J; Schaid, DJ; Schutt, AJ, 1991)
"Celecoxib was never discontinued for toxicity."2.73Impact of celecoxib on capecitabine tolerability and activity in pretreated metastatic breast cancer: results of a phase II study with biomarker evaluation. ( Carlini, P; Cognetti, F; Fabi, A; Ferretti, G; Gelibter, A; Melucci, E; Metro, G; Milella, M; Mottolese, M; Papaldo, P; Russillo, M; Sperduti, I; Tomao, S, 2008)
"Capecitabine is an orally administered precursor of 5'-deoxy-5-fluorouridine that was rationally designed to generate 5-fluorouracil (5-FU) preferentially in tumor tissue."2.73Safety profile and activity of lower capecitabine dose in patients with metastatic breast cancer. ( Alessandroni, P; Baldelli, AM; Casadei, V; Catalano, G; Catalano, V; Ceccolini, M; Fedeli, A; Fedeli, SL; Giordani, P; Rossi, D, 2007)
"Metastatic breast cancer remains an incurable disease and the median overall survival has not significantly improved over the past two decades."2.69Is salvage chemotherapy for metastatic breast cancer always effective and well tolerated? A phase II randomized trial of vinorelbine versus 5-fluorouracil plus leucovorin versus combination of mitoxantrone, 5-fluorouracil plus leucovorin. ( Comandini, D; Fusco, V; Merlini, L; Naso, C; Palumbo, R; Porcile, G; Pronzato, P; Repetto, L; Rosso, R; Simoni, C; Venturino, A, 2000)
"Fifty patients with advanced breast cancer were treated by high dose cisplatin (DDP) combination chemotherapy during the period of August 1984 to June 1991."2.67[High dose cisplatin combination chemotherapy for advanced breast cancer--a report on 50 cases]. ( Zhou, JC, 1993)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19909 (32.14)18.7374
1990's7 (25.00)18.2507
2000's10 (35.71)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, X1
Sanderson, SM1
Dai, Z1
Reid, MA1
Cooper, DE1
Lu, M1
Richie, JP1
Ciccarella, A1
Calcagnotto, A1
Mikhael, PG1
Mentch, SJ1
Liu, J1
Ables, G1
Kirsch, DG1
Hsu, DS1
Nichenametla, SN1
Locasale, JW1
Waters, SH1
Gillibrand, A1
Berry, H1
Kumar, S1
Velikova, G1
Dodwell, DJ1
Perren, TJ1
Wardley, AM1
Pivot, X1
Morales-Vasquez, F1
Zetina, LM1
de Fátima Dias Gaui, M1
Reyes, DO1
Jassem, J1
Barton, C1
Button, P1
Hersberger, V1
Torres, AA1
Birtle, AJ2
Newby, JC1
Harland, SJ1
Tytherleigh, MG1
Cohen, CE1
Glynne-Jones, R1
Livingstone, J1
Gilbert, J1
Yap, YS1
Kendall, A1
Walsh, G1
Banerji, U1
Johnston, SR1
Smith, IE1
O'Brien, M1
Wada, Y1
Hirayama, Y1
Seki, R1
Konuma, Y1
Kohda, K1
Yoshida, M1
Nakamura, Y1
Obata, M1
Ando, M1
Fabi, A1
Metro, G1
Papaldo, P1
Mottolese, M1
Melucci, E1
Carlini, P1
Sperduti, I1
Russillo, M1
Gelibter, A1
Ferretti, G1
Tomao, S1
Milella, M1
Cognetti, F1
Rossi, D1
Alessandroni, P1
Catalano, V1
Giordani, P1
Fedeli, SL1
Fedeli, A1
Baldelli, AM1
Casadei, V1
Ceccolini, M1
Catalano, G1
Traina, TA1
Theodoulou, M1
Feigin, K1
Patil, S1
Tan, KL1
Edwards, C1
Dugan, U1
Norton, L1
Hudis, C1
Takeuchi, S2
Akahoshi, Y1
Kasai, C2
Nishimoto, Y1
Citrin, DL1
Elson, P1
DeWys, WD1
Pinnamaneni, K1
Yap, HY1
Buzdar, AU2
Distefano, A1
Blumenschein, GR2
Valagussa, P1
Tess, JD1
Rossi, A1
Tancini, G1
Banfi, A1
Bonadonna, G1
Jardines, L1
Callans, LS1
Torosian, MH1
Hietanen, P1
Blomqvist, C1
Wasenius, VM1
Niskanen, E1
Franssila, K1
Nordling, S1
Zhou, JC1
Venturino, A1
Comandini, D1
Simoni, C1
Merlini, L1
Naso, C1
Palumbo, R1
Fusco, V1
Porcile, G1
Pronzato, P1
Rosso, R1
Repetto, L1
Nicholson, BP1
Paul, DM1
Hande, KR1
Shyr, Y1
Meshad, M1
Cohen, A1
Johnson, DH1
Pinedo, HM1
Kenis, Y1
Vaage, J1
Costanza, ME1
Legha, SS1
Smith, TL1
Hortobagyi, GN1
Swenerton, KD1
Gehan, EA1
Bodey, GP1
Freireich, EJ1
Sato, M1
Kushida, Y1
Matsunaga, T1
Loprinzi, CL1
Ingle, JN2
Schaid, DJ2
Buckner, JC2
Edmonson, JH1
Allegra, CJ1
Ahmann, DL1
Bisel, HF1
Schutt, AJ1
Long, HJ1
Rubin, J1
Porile, JL1
Olopade, OI1
Hoffman, PC1
Bolla, M1
Borgel, J1
Winckel, P1
Vrousos, C1
Swiercz, P1
Kreuter, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Single-blind, Multicenter, Parallel Group Clinical Trial to Assess Efficacy and Safety of NNG-TMAB (Trastuzumab) in Combination With Docetaxel on Recurrent or Metastatic Breast Cancer Patients With Positive HER2[NCT05301010]Phase 3128 participants (Actual)Interventional2018-02-02Completed
Randomized, Single-blind, Multicenter, Parallel Group Clinical Trial to Assess Pharmacokinetic Parameters, Safety of NNG-TMAB (Trastuzumab) in Combination With Docetaxel on Recurrent or Metastatic Breast Cancer Patients With Positive HER2.[NCT05301530]Phase 150 participants (Actual)Interventional2019-05-27Completed
A Prospective, Randomized, Open, Multi-center Phase III Clinical Study Comparing Efficacy and Safety of Sequential T-FEC and TX-XEC as Post-operative Adjuvant Chemotherapy Options for the Treatment of Triple-negative Breast Cancer[NCT01642771]Phase 3636 participants (Anticipated)Interventional2012-06-30Active, not recruiting
Randomized Open-label Trial of Dose Dense, Fixed Dose Capecitabine Compared to Standard Dose Capecitabine in Metastatic Breast Cancer and Advanced/Metastatic Gastrointestinal Cancers.[NCT02595320]Phase 2200 participants (Actual)Interventional2015-10-05Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for fluorouracil and Soft Tissue Neoplasms

ArticleYear
Recurrent breast cancer: presentation, diagnosis, and treatment.
    Seminars in oncology, 1993, Volume: 20, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Breast

1993
Chemotherapy of advanced soft-tissue sarcomas in adults.
    Cancer treatment reviews, 1977, Volume: 4, Issue:2

    Topics: Adult; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine;

1977

Trials

12 trials available for fluorouracil and Soft Tissue Neoplasms

ArticleYear
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Impact of celecoxib on capecitabine tolerability and activity in pretreated metastatic breast cancer: results of a phase II study with biomarker evaluation.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bone Neoplasms; Brain Neoplasms; Br

2008
Safety profile and activity of lower capecitabine dose in patients with metastatic breast cancer.
    Clinical breast cancer, 2007, Volume: 7, Issue:11

    Topics: Abdominal Neoplasms; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Breast Neoplas

2007
Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Apr-10, Volume: 26, Issue:11

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine;

2008
Treatment of metastatic prostate cancer. An analysis of response criteria in patients with measurable soft tissue disease.
    Cancer, 1984, Jul-01, Volume: 54, Issue:1

    Topics: Acid Phosphatase; Aged; Bone Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Evaluation; Fluo

1984
Do DNA ploidy and S-phase fraction in primary tumour predict the response to chemotherapy in metastatic breast cancer?
    British journal of cancer, 1995, Volume: 71, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclo

1995
[High dose cisplatin combination chemotherapy for advanced breast cancer--a report on 50 cases].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1993, Volume: 15, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cisplatin;

1993
Is salvage chemotherapy for metastatic breast cancer always effective and well tolerated? A phase II randomized trial of vinorelbine versus 5-fluorouracil plus leucovorin versus combination of mitoxantrone, 5-fluorouracil plus leucovorin.
    Breast cancer research and treatment, 2000, Volume: 60, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Femal

2000
Paclitaxel, 5-fluorouracil, and leucovorin (TFL) in the treatment of metastatic breast cancer.
    Clinical breast cancer, 2000, Volume: 1, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Comb

2000
Chemotherapy of advanced soft-tissue sarcomas in adults.
    Cancer treatment reviews, 1977, Volume: 4, Issue:2

    Topics: Adult; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine;

1977
5-Fluorouracil plus leucovorin in women with metastatic breast cancer. A phase II study.
    American journal of clinical oncology, 1991, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Fema

1991
A randomized trial of cyclophosphamide, doxorubicin, and prednisone versus cyclophosphamide, 5-fluorouracil, and prednisone in patients with metastatic breast cancer.
    American journal of clinical oncology, 1991, Volume: 14, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dox

1991

Other Studies

15 other studies available for fluorouracil and Soft Tissue Neoplasms

ArticleYear
Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
    Nature, 2019, Volume: 572, Issue:7769

    Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Diet; Disease Models, Animal; Female; Fluorouracil;

2019
Dose-finding study of weekly docetaxel, epirubicin and capecitabine, as first-line treatment in advanced breast cancer.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone

2009
Epirubicin carboplatin and 5-fluorouracil (ECarboF) chemotherapy in metastatic hormone refractory prostate cancer.
    British journal of cancer, 2004, Oct-18, Volume: 91, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; E

2004
Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2006, Volume: 4, Issue:6

    Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinom

2006
Clinical efficacy of capecitabine as first-line chemotherapy in metastatic breast cancer--how low can you go?
    Breast (Edinburgh, Scotland), 2007, Volume: 16, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Bone Neoplasms; Breast Neoplasms; Capecitabine; Deoxyc

2007
[Long- term remission survival with a case of rectal carcinoid tumor with metastasis in the soft tissue effectively treated with the combination therapy of irinotecan/5-fluorouracil/levofolinate followed by resection].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Nov-10, Volume: 96, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoid Tumor; Chemotherapy, Adjuvan

2007
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:9 Suppl

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide;

1984
Adriamycin, dibromodulcitol, and mitomycin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone.
    Cancer, 1984, May-01, Volume: 53, Issue:9

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neopla

1984
Adjuvant CMF effect on site of first recurrence, and appropriate follow-up intervals, in operable breast cancer with positive axillary nodes.
    Breast cancer research and treatment, 1981, Volume: 1, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide;

1981
Effects of combination drug therapy on the subcutaneous and pulmonary growth of a slow and a fast-growing C3H/He mammary carcinoma.
    Cancer research, 1979, Volume: 39, Issue:11

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combin

1979
Complete remissions in metastatic breast cancer treated with combination drug therapy.
    Annals of internal medicine, 1979, Volume: 91, Issue:6

    Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Castration; Cycloph

1979
[Clinical studies on preoperative continuous intra-arterial chemotherapy in the treatment of malignant soft tissue tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Cisplatin;

1991
Gastric adenocarcinoma presenting with soft tissue masses.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:1

    Topics: Adenocarcinoma; Aged; Fluorouracil; Humans; Male; Soft Tissue Neoplasms; Stomach Neoplasms; Thigh

1990
[Combination cisplatin, fluorouracil and low-dose radiotherapy in recurrent soft tissue sarcomas].
    Presse medicale (Paris, France : 1983), 1986, Mar-15, Volume: 15, Issue:11

    Topics: Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Sarcoma; Sof

1986
Poly(alkyl acrylate) nanoparticles.
    Methods in enzymology, 1985, Volume: 112

    Topics: Acrylic Resins; Animals; Antibody Formation; Antigens; Chemical Phenomena; Chemistry; Colloids; Dact

1985