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fluorouracil and Sjogren's Syndrome

fluorouracil has been researched along with Sjogren's Syndrome in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tenti, S1
Correale, P1
Conca, R1
Pastina, P1
Fioravanti, A1
Hareyama, M1
Nagakura, H1
Tamakawa, M1
Hyodo, K1
Asakura, K1
Horikoshi, T1
Oouchi, A1
Shido, M1
Morita, K1

Other Studies

2 other studies available for fluorouracil and Sjogren's Syndrome

ArticleYear
Occurrence of Sjögren syndrome in a long-term survivor patient with metastatic colon carcinoma treated with GOLFIG regimen.
    Journal of chemotherapy (Florence, Italy), 2012, Volume: 24, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Metronomic; Aged; Antineoplastic Combined Chemotherapy Proto

2012
Severe reaction after chemoradiotherapy of nasopharyngeal carcinoma with collagen disease.
    International journal of radiation oncology, biology, physics, 1995, Nov-01, Volume: 33, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Collagen Diseases; Combined Modality Ther

1995