fluorouracil has been researched along with Sigmoid Colon Diseases in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ulcer was relieved by conservative medical treatment." | 1.39 | [A case of an ulcer of the sigmoid colon during chemotherapy with FOLFOX4 and bevacizumab for recurrence of rectal carcinoma]. ( Hirata, K; Mizushima, Y; Okuya, K, 2013) |
| "We experienced a rare case of intussusception due to sigmoid colon cancer during chemotherapy." | 1.38 | [A case of intussusception due to sigmoid colon cancer during mFOLFOX6 therapy]. ( Fukino, N; Kano, H; Kawasaki, A; Kida, K; Kuboi, Y; Mimatsu, K; Oida, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cowman, S | 1 |
| Stebbing, J | 1 |
| Tuthill, M | 1 |
| Kida, K | 1 |
| Kawasaki, A | 1 |
| Mimatsu, K | 1 |
| Fukino, N | 1 |
| Kuboi, Y | 1 |
| Kano, H | 1 |
| Oida, T | 1 |
| Okuya, K | 1 |
| Mizushima, Y | 1 |
| Hirata, K | 1 |
| Melissas, J | 1 |
| Schoretsanitis, G | 1 |
| Daskalakis, M | 1 |
| Tsiftsis, DD | 1 |
| Tanaka, K | 1 |
| Kanamaru, T | 1 |
| Yamamoto, M | 1 |
1 review available for fluorouracil and Sigmoid Colon Diseases
| Article | Year |
|---|---|
Sigmoidoduodenal fistula as a rare complication of colonic carcinoma: report of a case.
Topics: Adenocarcinoma; Aged; Chemotherapy, Adjuvant; Colonic Neoplasms; Duodenal Diseases; Fluorouracil; Hu | 2003 |
4 other studies available for fluorouracil and Sigmoid Colon Diseases
| Article | Year |
|---|---|
Large bowel perforation associated with capecitabine treatment for breast cancer.
Topics: Aged; Breast Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Intestinal Perfor | 2008 |
[A case of intussusception due to sigmoid colon cancer during mFOLFOX6 therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Intussusception; Leuco | 2012 |
[A case of an ulcer of the sigmoid colon during chemotherapy with FOLFOX4 and bevacizumab for recurrence of rectal carcinoma].
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab | 2013 |
[A case of long-term survival of gastric cancer with peritoneal metastasis effectively treated by TS-1 and paclitaxel (PTX) combination therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Constriction, Pathologic; Drug Administra | 2006 |