fluorouracil has been researched along with Scotoma in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Scotoma: A localized defect in the visual field bordered by an area of normal vision. This occurs with a variety of EYE DISEASES (e.g., RETINAL DISEASES and GLAUCOMA); OPTIC NERVE DISEASES, and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pathology of the optic nerves revealed demyelination." | 1.29 | Ocular toxicity following high dose chemotherapy and autologous transplant. ( Elkordy, M; Hulette, C; Hussein, A; Jaffe, GJ; Khawly, JA; Peters, WP; Rubin, P; Vredenburgh, JJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rubin, P | 1 |
| Hulette, C | 1 |
| Khawly, JA | 1 |
| Elkordy, M | 1 |
| Hussein, A | 1 |
| Vredenburgh, JJ | 1 |
| Jaffe, GJ | 1 |
| Peters, WP | 1 |
1 other study available for fluorouracil and Scotoma
| Article | Year |
|---|---|
Ocular toxicity following high dose chemotherapy and autologous transplant.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Cispl | 1996 |