fluorouracil has been researched along with Sarcoidosis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gharavi, N | 1 |
| Diehl, J | 1 |
| Soriano, T | 1 |
| Marais, HJ | 1 |
| Page, PC | 1 |
2 other studies available for fluorouracil and Sarcoidosis
| Article | Year |
|---|---|
Cutaneous Sarcoidosis Successfully Treated With Intralesional 5-Fluorouracil.
Topics: Antimetabolites; Biopsy; Face; Fluorouracil; Humans; Injections, Intralesional; Male; Middle Aged; S | 2015 |
Treatment of equine sarcoid in seven Cape mountain zebra (Equus zebra zebra).
Topics: Animals; Antimetabolites, Antineoplastic; Combined Modality Therapy; Endangered Species; Equidae; Fe | 2011 |