fluorouracil has been researched along with Salmonella Infections, Animal in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Salmonella Infections, Animal: Infections in animals with bacteria of the genus SALMONELLA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The reduction in PMN was dose-dependent with a dosage of 200 mg/kg body weight of 5-FU, causing suppression of PMN to almost undetectable levels." | 1.29 | The effect of 5-fluorouracil treatment of chicks: a cell depletion model for the study of avian polymorphonuclear leukocytes and natural host defenses. ( Corrier, DE; DeLoach, JR; Hargis, BM; Kogut, MH; Tellez, G, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kogut, MH | 2 |
| Tellez, GI | 1 |
| McGruder, ED | 1 |
| Hargis, BM | 2 |
| Williams, JD | 1 |
| Corrier, DE | 2 |
| DeLoach, JR | 2 |
| Tellez, G | 1 |
| Kalutskiĭ, PV | 1 |
| Bel'skiĭ, VV | 1 |
3 other studies available for fluorouracil and Salmonella Infections, Animal
| Article | Year |
|---|---|
Heterophils are decisive components in the early responses of chickens to Salmonella enteritidis infections.
Topics: Animals; Chickens; Female; Fluorouracil; Granulocytes; Leukocyte Count; Liver; Male; Poultry Disease | 1994 |
The effect of 5-fluorouracil treatment of chicks: a cell depletion model for the study of avian polymorphonuclear leukocytes and natural host defenses.
Topics: Agranulocytosis; Animals; Chickens; Dose-Response Relationship, Drug; Fluorouracil; Lymphocyte Deple | 1993 |
[Effect of the immune system functioning of the body on the structure of Salmonella typhimurium populations according to the traits of antibiotic resistance and virulence].
Topics: Animals; Drug Resistance, Microbial; Fluorouracil; Immune System; Immunization; Immunologic Deficien | 1989 |